Browse Items (17 total)
- Tags: Inbred BALB C
Biocompatibility and in vivo tolerability of a new class of photoresponsive alkoxylphenacyl-based polycarbonates.
Tags: 2013, Alanine Transaminase/blood, Animals, Biocompatible Materials/chemistry/*metabolism/*toxicity, Cell Line, Chamsaz Elaheh A, Creatine/blood, Cytokines/analysis, Department of Pharmaceutical Sciences, Erythrocytes/drug effects, Hemolysis/drug effects, Inbred BALB C, Journal of pharmaceutical sciences, Joy Abraham, Kidney/drug effects/pathology, Light, Liver/drug effects/pathology, Macrophages/cytology/drug effects, Mice, NEOMED College of Pharmacy, Oyewumi Moses O, Polycarboxylate Cement/chemistry/*metabolism/*toxicity, Rats, Sprague-Dawley, Sun Shuangyi, Wehrung Daniel
Striatal dopamine output is compromised within +/- BDNF mice.
Tags: 2002, Anderson Linda I, Animals, Brain-Derived Neurotrophic Factor/*deficiency/genetics, Dluzen Dean E, Dopamine/*metabolism, Drug Interactions/physiology, Extracellular Space/drug effects/metabolism, Female, Genotype, Inbred BALB C, Knockout, Kucera Jan, Male, McDermott Janet L, Methamphetamine/pharmacology, Mice, Neostriatum/drug effects/*metabolism/physiopathology, Neural Pathways/drug effects/*metabolism/physiopathology, Neurons/drug effects/*metabolism, Parkinsonian Disorders/genetics/*metabolism/physiopathology, Perfusion/methods, Potassium/metabolism/pharmacology, Substantia Nigra/drug effects/*metabolism/physiopathology, Synapse (New York, N.Y.), Walro Jon M
The ability of an HSV strain to initiate zosteriform spread correlates with its neuroinvasive disease potential.
Tags: 2002, Animal, Animals, Archives of virology, Disease Models, Docherty J J, Ganglia, Goel N, Herpes Simplex/*physiopathology/virology, Herpesvirus 1, Human/*pathogenicity, Inbred BALB C, Mao H, Mice, Rong Q, Rosenthal K S, Skin Diseases/*physiopathology/virology, Spinal/*virology, Time Factors, Virulence, Zimmerman D
Lipopolysaccharide supports maintaining the stemness of CD133(+) hepatoma cells through activation of the NF-kappaB/HIF-1alpha pathway.
Tags: *Cancer stem cells, *Lipopolysaccharide, *Plasticity, *Stemness maintenance, *Tumor microenvironment, 2016, AC133 Antigen/genetics/*metabolism, alpha Subunit/genetics/*metabolism, Animals, Antineoplastic Agents – Pharmacodynamics, Antineoplastic Agents/pharmacology, Body Weights and Measures, Cancer letters, Carcinoma, Cell Line, Cell Movement – Drug Effects, Cell Movement/drug effects, Cell Physiology, Cell Physiology – Drug Effects, Cell Proliferation/drug effects, Department of Integrative Medical Sciences, Drug Resistance, Gene Expression Regulation, Genes, Genetic Techniques, Han Zhi-Peng, Hepatocellular, Hepatocellular – Drug Therapy, Hepatocellular – Metabolism, Hepatocellular – Pathology, Hepatocellular/drug therapy/genetics/*metabolism/pathology, Humans, Hypoxia-Inducible Factor 1, Inbred BALB C, Jing Ying-Ying, Lai Fo-Bao, Li Rong, Li Xiao-Yong, Lipopolysaccharides – Pharmacodynamics, Lipopolysaccharides/*pharmacology, Liu Jing-Feng, Liu Wen-Ting, Liver Neoplasms, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms/drug therapy/genetics/*metabolism/pathology, Male, Mice, NEOMED College of Medicine, Neoplasm, Neoplasm Invasiveness, Neoplastic, Neoplastic Stem Cells/*drug effects/metabolism/pathology, NF-kappa B – Metabolism, NF-kappa B/*metabolism, Nude, Pan Xiao-Rong, Phenotype, Proteins, Proteins – Metabolism, RNA Interference, Shi Rong-Yu, Signal Transduction – Drug Effects, Signal Transduction/drug effects, Stem Cells – Drug Effects, Stem Cells – Metabolism, Stem Cells – Pathology, Time Factors, Transfection, Tumor Burden, Tumor Microenvironment, Wei Li-Xin, Wu Meng-Chao, Yang Xue, Yu Guo-Feng, Zeng Jian-Xing, Zhang Hang-Jie, Zhang Ping, Zhao Qiu-Dong
Effects of gelucire content on stability, macrophage interaction and blood circulation of nanoparticles engineered from nanoemulsions.
Tags: 2012, Animals, ATP Binding Cassette Transporter, Calorimetry, Colloids and surfaces. B, Biointerfaces, Department of Pharmaceutical Sciences, Differential Scanning, Drug Carriers/*chemical synthesis/pharmacokinetics, Drug Stability, Emulsions/chemistry, Fatty Alcohols/*chemistry, Fourier Transform Infrared, Geldenhuys Werner J, Humans, Inbred BALB C, Macrophages/*drug effects/metabolism, Member 1/metabolism, Mice, Nanoparticles/*chemistry/ultrastructure, NEOMED College of Pharmacy, Oils/chemistry, Oyewumi Moses O, Paclitaxel/pharmacokinetics, Particle Size, Polyethylene Glycols/*chemistry, Reactive Oxygen Species/metabolism, Rhodamine 123/metabolism, Spectroscopy, Subfamily B, Water/chemistry, Wehrung Daniel
Formulation and photoirradiation parameters that influenced photoresponsive drug delivery using alkoxylphenacyl-based polycarbonates.
Tags: 2014, Animals, Biocompatibility, Cardiotoxicity, Cell Line, Chamsaz Elaheh A, Chemistry, Department of Pharmaceutical Sciences, Dose-Response Relationship, Doxorubicin, Drug, Drug Delivery Systems/*methods, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Heart/drug effects, Humans, Inbred BALB C, Joy Abraham, Mice, Nanotechnology, NEOMED College of Pharmacy, Oyewumi Moses O, Pharmaceutical, Photic Stimulation/*methods, Photoresponsive, Photosensitizing Agents/*chemical synthesis/radiation effects/toxicity, Polycarboxylate Cement/*chemical synthesis/radiation effects/toxicity, Polymer chain scission, Stimuli-responsive, Tumor, Wehrung Daniel
Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.
Tags: 2016, Al-Azzam Nosayba, Animals, Boyce Joshua A, c-fos, Capillary Permeability, Cell Line, CysLT(1)R, Department of Integrative Medical Sciences, Dinoprostone/*immunology, Duah Ernest, E-prostanoid receptor 3, Edema/immunology, EP3 Subtype/*immunology, extracellular signal-regulated kinase, Humans, Inbred BALB C, Inbred C57BL, Inflammation/immunology, Kondeti Vinay, leukotriene D(4), Leukotriene D4/*immunology, Leukotriene/*immunology, macrophage inflammatory protein 1beta, Mast cells, Mast Cells/*immunology, Mice, NEOMED College of Medicine, Paruchuri Sailaja, prostaglandin D(2), Prostaglandin E, prostaglandin E(2), protein kinase G, Receptors, The Journal of allergy and clinical immunology, Thodeti Charles K, Transgenic, Tumor
A modification of the epidermal scarification model of herpes simplex virus infection to achieve a reproducible and uniform progression of disease.
Tags: *Herpesvirus 1, 2002, Animal, Animals, Disease Models, Disease Progression, Docherty John J, Female, Fu Ming Ming, Goel Neena, Herpes Simplex/pathology/physiopathology/*transmission, Human, Humans, Inbred BALB C, Journal of virological methods, Mice, Reproducibility of Results, Rosenthal Kenneth S, Skin/virology, Zimmerman Daniel H
A L.E.A.P.S. heteroconjugate vaccine containing a T cell epitope from HSV-1 glycoprotein D elicits Th1 responses and protection.
Tags: 2003, Amino Acid Sequence, Animals, CD4-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/immunology, Conjugate/immunology, Delayed/immunology, Enzyme-Linked Immunosorbent Assay, Epitopes/*immunology, Female, Goel N, Herpes Simplex Virus Vaccines/*immunology, Herpes Simplex/pathology/prevention & control, Herpesvirus 1, Human/*immunology, Hypersensitivity, Inbred BALB C, Interferon-gamma/biosynthesis, Lymphocyte Count, Mice, Molecular Sequence Data, Peptides/immunology, Rong Q, Rosenthal K S, Th1 Cells/*immunology, Vaccine, Vaccines, Viral Envelope Proteins/*immunology, Zimmerman D
Immunization with a LEAPS heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1.
Tags: *Epitopes, 1999, Amino Acid Sequence, Animals, beta 2-Microglobulin/immunology, Conjugate/immunology, Cytotoxic/*immunology, Delayed/*etiology, Female, Herpesvirus 1, Horne W I, Human/*immunology, Hypersensitivity, Immediate-Early Proteins/*immunology, Immunization, Inbred BALB C, Mao H, Mice, Molecular Sequence Data, Peptide Fragments/*immunology, Rosenthal K S, T-Lymphocyte, T-Lymphocytes, Vaccine, Vaccines, Viral Vaccines/*immunology, Wright C, Zimmerman D
LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis.
Tags: 2016, Affo Silvia, Alcoholic/*immunology, Altamirano Jose, Animals, Arroyo Vicente, Bataller Ramon, Caballeria Juan, Cell Proliferation, Cells, Chen Jiegen, Collagen/genetics/metabolism, Common/*pathology, Crews Fulton, Cultured, Department of Pharmaceutical Sciences, Dumitru Raluca, Female, Gene Expression Profiling, Gene Expression Regulation, Gines Pere, Hepatic Duct, Hepatitis, Hepatocytes/*metabolism/pathology, Humans, Inbred BALB C, Keratins, Knockout, Lipopolysaccharides/metabolism, Lozano Juan Jose, Male, Matsushita Hiroshi, Mice, Middle Aged, Morales-Ibanez Oriol, NEOMED College of Pharmacy, Odena Gemma, Rautou Pierre-Emmanuel, Rodrigo-Torres Daniel, Sancho-Bru Pau, Scientific reports, Seki Ekihiro, Signal Transduction, Toll-Like Receptor 4/genetics/*metabolism, Type I/genetics/*metabolism, Valla Dominique, You Min, Zou Jian
Impairment of Hematopoietic Precursor Cell Activation during the Granulopoietic Response to Bacteremia in Mice with Chronic-Plus-Binge Alcohol Administration.
Tags: *alcohol, *bacteremia, *cell signaling, *granulocytes, *granulopoietic response, *Stem cells, 2017, Animal, Animals, Antigens, Bacteremia/genetics/*immunology/pathology, Binge Drinking/genetics/*immunology/pathology, Bone Marrow Cells/drug effects/immunology/pathology, CCAAT-Enhancer-Binding Protein-beta/genetics/immunology, Cyclin D1/genetics/immunology, Department of Integrative Medical Sciences, Disease Models, Escherichia coli Infections/genetics/*immunology/pathology, Escherichia coli/growth & development/immunology, Ethanol/*pharmacology, Gao Bin, Gene Expression Regulation/*drug effects/immunology, Granulocytes/drug effects/immunology/pathology, Hematopoiesis/*drug effects/genetics/immunology, Inbred BALB C, Infection and immunity, Lin Yuan-Ping, Ly/genetics/immunology, Male, Membrane Proteins/genetics/immunology, Mice, Mitogen-Activated Protein Kinase 1/genetics/immunology, Mitogen-Activated Protein Kinase 3/genetics/immunology, NEOMED College of Medicine, Nucleotidyltransferases/deficiency/genetics/immunology, Proto-Oncogene Proteins c-kit/genetics/immunology, Shi Xin, Signal Transduction/*drug effects/immunology, Toll-Like Receptor 4/genetics/immunology, Zhang Ping
Strain-dependent structural variants of herpes simplex virus type 1 ICP34.5 determine viral plaque size, efficiency of glycoprotein processing, and viral release and neuroinvasive disease potential.
Tags: *Genetic Variation, 2003, Animals, Cercopithecus aethiops, Cultured, Encephalitis, Genetic, Herpes Simplex/*physiopathology/virology, Herpesvirus 1, Human/*classification/genetics/*pathogenicity, Inbred BALB C, Journal of virology, Male, Mao Hanwen, Mice, Recombination, Rosenthal Ken S, Transfection, Tumor Cells, Vero Cells, Viral Envelope Proteins/metabolism, Viral Plaque Assay, Viral Proteins/*chemistry/*genetics/metabolism
LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model.
Tags: *Cancer Vaccines/genetics/immunology/therapeutic use, 2017, Animal, Animals, Breast Neoplasms/genetics/immunology/prevention & control/therapy, CD8-Positive T-Lymphocytes/immunology, Cell Line, Cytotoxic/immunology, Disease Models, Disease Progression, Epitopes, erbB-2, Experimental/immunology/pathology/*prevention & control/*therapy, Female, Genes, Immunoglobulin G/blood, Inbred BALB C, Journal of immunology research, Koski Gary, Mammary Neoplasms, Mice, Neoplasm Metastasis/prevention & control, Proof of Concept Study, Rosenthal Ken S, Stone Sarah, T-Lymphocyte/immunology, T-Lymphocytes, Tumor, Zimmerman Daniel H
Therapeutic Delivery of Simvastatin Loaded in PLA-PEG Polymersomes Resulted in Amplification of Anti-inflammatory Effects in Activated Microglia.
Tags: *Drug Delivery Systems, *Inflammation, *Microglia, *neuroprotection, *polymersomes, *simvastatin, 2017, Animals, Anti-Inflammatory Agents/*pharmacology, Department of Pharmaceutical Sciences, Inbred BALB C, Interleukin-6/antagonists & inhibitors/biosynthesis, Lactates/*administration & dosage, Manickavasagam Dharani, Mice, Microglia/*drug effects, NEOMED College of Pharmacy, Nitric Oxide/antagonists & inhibitors/biosynthesis, Novak Kimberly, Oyewumi Moses O, Polyethylene Glycols/*administration & dosage, Simvastatin/*administration & dosage/pharmacology, The AAPS journal, Tumor Necrosis Factor-alpha/antagonists & inhibitors/biosynthesis
Intrastrain variants of herpes simplex virus type 1 isolated from a neonate with fatal disseminated infection differ in the ICP34.5 gene, glycoprotein processing, and neuroinvasiveness.
Tags: *Genetic Variation, *Protein Processing, 1999, Amino Acid, Amino Acid Sequence, Animal, Animals, Base Sequence, Bower J R, Deoxyribonuclease BamHI, Deoxyribonuclease EcoRI, Detwiler M, Disease Models, DNA, Durishin C, Genes, Glycoproteins/metabolism, Herpesvirus 1, Human/*genetics/growth & development/isolation & purification, Humans, Inbred BALB C, Journal of virology, Karban T L, Male, Mao H, Mice, Molecular Sequence Data, Nucleic Acid, Polymerase Chain Reaction/methods, Polymorphism, Post-Translational, Rempinski D, Restriction Fragment Length, Rosenthal K S, Rozenbom E, Sequence Analysis, Sequence Homology, Viral, Viral Envelope Proteins/analysis, Viral Proteins/*genetics
Antitumor effect of novel silatranes on renal cell carcinoma in mice.
Tags: *Bridged Bicyclo Compounds, *Organosilicon Compounds, 1992, Animals, Anticancer research, Antineoplastic Agents/pharmacology/*therapeutic use, Bridged Bicyclo Compounds/pharmacology/*therapeutic use, Carcinoma, Female, Grna A, Heterocyclic, Hogan J, Inbred BALB C, Kidney Neoplasms/*drug therapy, Koo P H, Mice, Renal Cell/*drug therapy, Silicon/pharmacology/*therapeutic use, Structure-Activity Relationship