Browse Items (7 total)
- Tags: Inbred DBA
Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma.
Tags: 2018, AMP-activated protein kinase, AMP-Activated Protein Kinases/*metabolism, Animal, Animals, Biological, Calcium Binding Proteins – Metabolism, Calcium-Binding Proteins/metabolism, Cells – Drug Effects, Cells – Pathology, Department of Pharmaceutical Sciences, Diet, Disease Models, Eye Proteins/genetics, Female, G-Protein-Coupled – Metabolism, G-Protein-Coupled/*metabolism, Glaucoma, Glaucoma – Complications, Glaucoma – Pathology, Glaucoma/*complications/pathology, Harun-Or-Rashid Mohammad, Impact of Events Scale, Inbred DBA, Inflammation – Etiology, Inflammation – Prevention and Control, Inflammation hydroxycarboxylic acid receptor, Inflammation/*etiology/*prevention & control, Inman Denise M, Journal of neuroinflammation, Ketogenic diet, Ketogenic/methods, Male, Membrane Glycoproteins, Membrane Glycoproteins/genetics, Mice, Microfilament Proteins – Metabolism, Microfilament Proteins/metabolism, Microglia/drug effects/pathology, Models, Mutation, Mutation/genetics, NEOMED College of Pharmacy, Neuroprotection/drug effects/*physiology, NLR Family, Optic Nerve – Pathology, Optic Nerve/pathology, Phosphotransferases – Metabolism, Proteins, Pyrin Domain-Containing 3 Protein/genetics/metabolism, Receptors, Retina – Drug Effects, Retina – Pathology, Retinal Ganglion Cells/drug effects/*pathology, Transgenic
Mitochondrial morphology differences and mitophagy deficit in murine glaucomatous optic nerve.
Tags: *Disease Models, 2015, Adenosine Triphosphate/metabolism, Age Factors, Animal, Animals, autophagosome, Axons/pathology, Coughlin Lucy, Department of Pharmaceutical Sciences, Electron, Horner Philip J, Inbred DBA, Inman Denise M, Investigative ophthalmology & visual science, Mice, Microscopy, Mitochondria, Mitochondria/*pathology, Mitochondrial Degradation/*physiology, mitophagy, Morrison Richard S, Myelinated/pathology, NEOMED College of Pharmacy, Nerve Fibers, Optic Nerve/*pathology
Mutation in Osteoactivin Promotes Receptor Activator of NFkappaB Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function.
Tags: *Mutation, 2015, Abdelmagid Samir M, Akt, Animals, Belcher Joyce Y, Bone, bone marrow, Bone Remodeling, Cell Differentiation/*physiology, Cell Survival/*physiology, Department of Anatomy & Neurobiology, Eye Proteins/*genetics, Hankenson Kurt D, Inbred DBA, Khol Matthew, Malcuit Christopher, MAP kinases (MAPKs), Mbimba Thomas, Membrane Glycoproteins/*genetics, Mice, Moussa Fouad M, NEOMED College of Medicine, Novak Kimberly, OSTEOACTIVIN, osteoclast, Osteoclasts/*cytology, osteopetrosis, RANK Ligand/metabolism/*physiology, Safadi Fayez F, Signal Transduction, Sondag Gregory R, Stinnett Hilary, The Journal of biological chemistry, X-Ray Microtomography, Yu Bing
Postnatal developmental changes in the medial nucleus of the trapezoid body in a mouse model of auditory pathology.
Tags: *Disease Models, 2014, AHL, Animal, Animals, Auditory brainstem responses, Auditory Pathways/*growth & development/*pathology, Auditory system, DBA/2, Grimsley Calum A, Hearing Loss/*pathology, Inbred CBA, Inbred DBA, Mice, MNTB, Neuroscience letters, Newborn, Olivary Nucleus/*growth & development/*pathology, Organ Culture Techniques, Sivaramakrishnan Shobhana
Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma.
Tags: *Astrocyte, *Axonopathy, *Glaucoma, *Gliosis, *neurodegeneration, *Retinal ganglion cell, 2016, Animal, Animals, Astrocytes/*pathology, Axons/pathology, Calkins David J, Cooper Melissa L, Crish Samuel D, Department of Pharmaceutical Sciences, Disease Models, Experimental eye research, Glaucoma, Horner Philip J, Imaging, Inbred DBA, Inman Denise M, Mice, NEOMED College of Pharmacy, Nerve Degeneration/etiology/*pathology, Open-Angle/*pathology, Optic Nerve Diseases/etiology/*pathology, Optic Nerve/*pathology, Photomicrography, Retinal Ganglion Cells/*pathology, Three-Dimensional, Time Factors
Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro.
Tags: *Signal Transduction, 2014, Abdelmagid Samir M, Alkaline Phosphatase/metabolism, Animals, Apoptosis, Belcher Joyce Y, Bone and Bones/metabolism/pathology, Cell Differentiation/genetics, Del Carpio-Cano Fabiola E, Department of Anatomy & Neurobiology, Eye Proteins/*genetics, Frara Nagat A, Inbred DBA, Lababidi Suzanne L, Male, Membrane Glycoproteins/*genetics, Mice, Moussa Fouad M, Mutation, NEOMED College of Medicine, Newborn, Novak Kimberly M, Osteoblasts/cytology/*physiology, Osteocalcin/*genetics, Osteogenesis/*genetics, Phenotype, Razmpour Roshanak, Receptors, Safadi Fayez F, Sanyurah Afif S, Sondag Gregory R, The American journal of pathology, Transforming Growth Factor beta/metabolism
Persistence of intact retinal ganglion cell terminals after axonal transport loss in the DBA/2J mouse model of glaucoma.
Tags: *Axonal Transport/physiology, *bouton, *Mitochondria, *neurodegeneration, *retinal, *RRID:IMSRJAX:000671, *RRID:IMSRJAX:007048, *RRID:SCR002716, *RRID:SCR002865, *superior colliculus, *synapse, 2016, Animal, Animals, Crish Samuel D, Dengler-Crish Christine M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Disease Models, Electron, Fening Kelly M, Glaucoma/metabolism/*pathology, Imaging, Inbred DBA, Inman Denise M, Mice, Microscopy, Mitochondria/pathology, NEOMED College of Medicine, NEOMED College of Pharmacy, Neuroanatomical Tract-Tracing Techniques, Regression Analysis, Retinal Ganglion Cells/metabolism/*pathology, Scanning, Schofield Brett R, Smith Matthew A, Superior Colliculi/metabolism/*pathology, Synapses/metabolism/*pathology, The Journal of comparative neurology, Three-Dimensional, Visual Pathways/metabolism/pathology, Xia Christina Z