1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/jappl.1994.77.6.2720" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/jappl.1994.77.6.2720</a>
Pages
2720–2726
Issue
6
Volume
77
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Time course of blood volume changes in an isolated lung lobe after venous pressure elevation.
Publisher
An entity responsible for making the resource available
Journal of applied physiology (Bethesda, Md. : 1985)
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
1994-12
Subject
The topic of the resource
*Blood Volume/drug effects; *Pulmonary Circulation; *Venous Pressure; Animals; Dogs; Extravascular Lung Water/metabolism; Female; In Vitro Techniques; Indicator Dilution Techniques; Indocyanine Green; Lung/*physiology; Male; Papaverine/pharmacology; Perfusion; Time Factors
Creator
An entity primarily responsible for making the resource
Maron M B; Lane S M
Description
An account of the resource
The elevation of venous pressure (Pv) in isolated perfused organs causes organ weight to increase in a biphasic manner. The initial rapid phase results primarily from an increase in blood volume (BV), whereas the second slower phase is generally considered to reflect fluid filtration. Recent studies have suggested, however, that BV may continue to increase during the slow weight gain phase. To address this question, we made serial measurements of circulating BV by indicator dilution with indocyanine green dye in a canine isolated perfused left lower lung lobe (LLL) preparation during 40 min of Pv elevation. Pv was raised to approximately 18 Torr in six LLLs beginning an average of 28 min after the start of perfusion. After an initial rapid increase, BV continued to increase at a slower rate for approximately 30 min. The increase in BV observed between 3 and 40 min of Pv elevation [4.3 +/- 0.3 (SE) ml] was 47.9 +/- 9.1% of the weight gain that occurred during this period. In six additional LLLs, Pv elevation was delayed until approximately 70 min after the perfusion was started. In these LLLs, BV generally achieved constancy 3 min after Pv was elevated. These data indicate that the dynamics of the BV response of this preparation to Pv elevation is time dependent and that gravimetric determinations of the rate of fluid filtration may substantially overestimate the true filtration rate in the presence of continuing increases in BV. The increases in BV observed in the first group of LLLs appear to be due to vascular recruitment rather than stress relaxation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/jappl.1994.77.6.2720" target="_blank" rel="noreferrer noopener">10.1152/jappl.1994.77.6.2720</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Blood Volume/drug effects
*Pulmonary Circulation
*Venous Pressure
1994
Animals
Dogs
Extravascular Lung Water/metabolism
Female
In Vitro Techniques
Indicator Dilution Techniques
Indocyanine Green
Journal of applied physiology (Bethesda, Md. : 1985)
Lane S M
Lung/*physiology
Male
Maron M B
Papaverine/pharmacology
Perfusion
Time Factors
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s001340050287" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s001340050287</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
31-37
Issue
1
Volume
23
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The effects of low dose dopamine on splanchnic blood flow and oxygen uptake in patients with septic shock
Publisher
An entity responsible for making the resource available
Intensive Care Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
1997-01
Subject
The topic of the resource
sepsis; injury; oxygen consumption; General & Internal Medicine; epinephrine; dopamine; index; septic shock; oxygen delivery; critically ill patients; consumption; blood flow; endotoxemia; gastric-mucosal ph; indocyanine green; splanchnic; splanchnic oxygen; splanchnic oxygen delivery
Creator
An entity primarily responsible for making the resource
MeierHellmann A; Bredle D L; Specht M; Spies C; Hannemann L; Reinhart K
Description
An account of the resource
Objective. To assess the effects of low-dose dopamine on splanchnic blood flow and splanchnic oxygen uptake in patients with septic shock. Design. Prospective, controlled trial. Setting. University hospital intensive care unit. Patients. 11 patients with septic shock, diagnosed according the criteria of the 1992 American College of Chest Physicians/Society of Critical Care Medicine consensus conference, who required treatment with norepinephrine. Measurements and main results: Systemic and splanchnic hemodynamics and oxygen transport were measured before and during addition of low-dose dopamine (3 mu g/kg per min). Low-dose dopamine had a marked effect on total body hemodynamics and oxygen transport. The fractional splanchnic flow at baseline ranged from 0.15 to 0.57. In 7 patients with a fractional splanchnic flow less than 0.30, low-dose dopamine increased splanchnic flow and splanchnic oxygen delivery and oxygen consumption. In 4 patients with a fractional splanchnic flow above 0.30, low-dose dopamine did not appear to change splanchnic blood flow. Conclusion: Low-dose dopamine has a potential beneficial effect on splanchnic blood flow and oxygen consumption in patients with septic shock, provided the fractional splanchnic flow is not already high before treatment.
Identifier
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<a href="http://doi.org/10.1007/s001340050287" target="_blank" rel="noreferrer noopener">10.1007/s001340050287</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1997
blood flow
Bredle D L
consumption
Critically Ill Patients
Dopamine
endotoxemia
Epinephrine
gastric-mucosal ph
General & Internal Medicine
Hannemann L
index
Indocyanine Green
Injury
Intensive Care Medicine
Journal Article or Conference Abstract Publication
Meierhellmann A
Oxygen Consumption
oxygen delivery
Reinhart K
sepsis
Septic shock
Specht M
Spies C
splanchnic
splanchnic oxygen
splanchnic oxygen delivery
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/00003246-199703000-00005" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/00003246-199703000-00005</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
399-404
Issue
3
Volume
25
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Epinephrine impairs splanchnic perfusion in septic shock
Publisher
An entity responsible for making the resource available
Critical Care Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
1997-03
Subject
The topic of the resource
sepsis; oxygen consumption; General & Internal Medicine; epinephrine; agents; septic shock; norepinephrine; oxygen delivery; critically ill patients; intramural ph; tissue oxygenation; blood flow; oxygen consumption; gastric-mucosal ph; indocyanine green; splanchnic; splanchnic oxygen delivery; dobutamine; hepatic blood-flow; splanchnic oxygen consumption; vasoactive
Creator
An entity primarily responsible for making the resource
MeierHellmann A; Reinhart K; Bredle D L; Specht M; Spies C D; Hannemann L
Description
An account of the resource
Objective: To assess the effects of epinephrine on splanchnic perfusion and splanchnic oxygen uptake in patients with septic shock. Design: Prospective, controlled trial. Setting: University hospital intensive care unit (ICU). Patients: Eight patients with septic shock, according to the criteria of the 1992 American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference, requiring treatment with vasopressors. Interventions: We compared in crossover design a 2-hr infusion of epinephrine with dobutamine plus norepinephrine in eight ICU patients with septic shock, Systemic and splanchnic hemodynamics and oxygen transport were measured before and during treatment with epinephrine. Measurements and Main Results: There was essentially no effect of epinephrine on the global parameters, except for increased lactate concentrations, There were marked effects on the regional variables; epinephrine caused lower splanchnic flow and oxygen uptake, lower mucosal pH, and higher hepatic vein lactate. Conclusion: We conclude that undesirable splanchnic effects on patients in whom that region is particularly fragile should be considered when using epinephrine for septic shock treatment.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/00003246-199703000-00005" target="_blank" rel="noreferrer noopener">10.1097/00003246-199703000-00005</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1997
agents
blood flow
Bredle D L
Critical care medicine
Critically Ill Patients
dobutamine
Epinephrine
gastric-mucosal ph
General & Internal Medicine
Hannemann L
hepatic blood-flow
Indocyanine Green
intramural ph
Journal Article or Conference Abstract Publication
Meierhellmann A
Norepinephrine
Oxygen Consumption
oxygen delivery
Reinhart K
sepsis
Septic shock
Specht M
Spies C D
splanchnic
splanchnic oxygen consumption
splanchnic oxygen delivery
tissue oxygenation
vasoactive