Browse Items (44 total)
- Tags: Inflammation
Butein Activates Autophagy Through AMPK/TSC2/ULK1/mTOR Pathway to Inhibit IL-6 Expression in IL-1beta Stimulated Human Chondrocytes.
Tags: 2018, Ahmad Nashrah, AMP-Activated Protein Kinases/metabolism, AMPK, Ansari Mohammad Y, Articular/cytology/pathology, Autophagy, Autophagy-Related Protein 5/antagonists & inhibitors/genetics/metabolism, Autophagy-Related Protein-1 Homolog/metabolism, Autophagy/*drug effects, Butein, Cartilage, Cell Survival/drug effects, Cells, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Chalcones/*pharmacology, Chondrocytes/cytology/drug effects/metabolism, Cultured, Department of Anatomy & Neurobiology, Haqqi Tariq M, Humans, Inflammation, Interleukin-1beta/*pharmacology, Interleukin-6/genetics/*metabolism, Intracellular Signaling Peptides and Proteins/metabolism, mTOR, NEOMED College of Medicine, Osteoarthritis, Osteoarthritis/metabolism/pathology, Phosphorylation/drug effects, Reactive Oxygen Species/metabolism, RNA, RNA Interference, Signal Transduction/*drug effects, Small Interfering/metabolism, TOR Serine-Threonine Kinases/metabolism, TSC2, Tuberous Sclerosis Complex 2 Protein, Tumor Suppressor Proteins/metabolism, ULK1
Role of inflammation in the aging bones.
Tags: *Models, 2015, Abdelmagid Samir M, Aging, Aging/*physiology, Animals, Barbe Mary F, Biological, Bone adaptation, Bone and Bones/cytology/immunology/*physiopathology, Bone Marrow Cells/physiology, Bone resorption, Cell Differentiation/*physiology, Cumulative Trauma Disorders/physiopathology, Department of Anatomy & Neurobiology, Humans, Inflammation, Inflammation/*physiopathology, Life sciences, Macrophages, Macrophages/*physiology, NEOMED College of Medicine, Osteoblasts, Osteoblasts/*physiology, Osteoclasts, Osteoclasts/*physiology, Safadi Fayez F
Bile acid receptors in non-alcoholic fatty liver disease.
Tags: 2013, Animals, Bile Acids and Salts/*metabolism, Biochemical pharmacology, Cholesterol, Cytoplasmic and Nuclear/agonists/*metabolism, Fatty Liver/drug therapy/immunology/*metabolism, FXR, G-Protein-Coupled/agonists/*metabolism, Glucose/metabolism, Humans, Inflammation, Jadhav Kavita, Li Yuanyuan, Lipid Metabolism/drug effects, Lipid Regulating Agents/chemistry/pharmacology/therapeutic use, Molecular Structure, Non-alcoholic Fatty Liver Disease, Receptors, TGR5, Triglyceride, Triglycerides/metabolism, Zhang Yanqiao
Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis.
Tags: 2014, Animals, Anti-Inflammatory Agents/pharmacology, Anticarcinogenic Agents/*pharmacology, Antineoplastic Agents/*pharmacology, Apoptosis/drug effects, Bhatia Deepak, Bishayee Anupam, Breast Neoplasms/*drug therapy/metabolism, breast tumor, Carcinogenesis/*drug effects, Cell Proliferation/drug effects, Chemoprevention/methods, COX-2, Cyclooxygenase 2/metabolism, DMBA, Down-Regulation/drug effects, Experimental/*drug therapy/metabolism, Female, HSP90, HSP90 Heat-Shock Proteins/metabolism, I-kappa B Proteins/metabolism, Inflammation, Inflammation/*drug therapy/metabolism, Mammary Neoplasms, Mandal Animesh, Molecular carcinogenesis, NF-kappa B/metabolism, NF-kappaB, NF-KappaB Inhibitor alpha, oleanane triterpenoid, Oleanolic Acid/*analogs & derivatives/pharmacology, Rats, Sprague-Dawley