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Tags: Inhibitory Postsynaptic Potentials/drug effects/physiology

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Activation of synaptic group II metabotropic glutamate receptors induces long-term depression at GABAergic synapses in CNS neurons.

Metabotropic glutamate receptor (mGluR)-dependent homosynaptic long-term depression (LTD) has been studied extensively at glutamatergic synapses in the CNS. However, much less is known about heterosynaptic long-term plasticity induced by mGluRs at…

Tags: 2013, Amino Acids/pharmacology, Animals, Chick Embryo, Cochlear Nucleus/drug effects/metabolism, Curry Rebecca J, Cyclopropanes/pharmacology, Department of Anatomy & Neurobiology, Dinh Emilie Hoang, Excitatory Amino Acid Agonists/pharmacology, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/drug effects/physiology, GABAergic Neurons/drug effects/*metabolism, Glycine/analogs & derivatives/pharmacology, Hamlet William R, Inhibitory Postsynaptic Potentials/drug effects/physiology, Liu Yu-Wei, Long-Term Synaptic Depression/drug effects/*physiology, Lu Yong, Metabotropic Glutamate/agonists/antagonists & inhibitors/*metabolism, NEOMED College of Medicine, Neural Inhibition/drug effects/physiology, Receptors, Shi Wei, Synapses/drug effects/*metabolism, Synaptic Transmission/drug effects/*physiology, Tang Zheng-Quan, The Journal of neuroscience : the official journal of the Society for Neuroscience, Xanthenes/pharmacology

Control of a depolarizing GABAergic input in an auditory coincidence detection circuit.

Neurons in the chicken nucleus laminaris (NL), the third-order auditory neurons that detect the interaural time differences that enable animals to localize sounds in the horizontal plane, receive glutamatergic excitation from the cochlear nucleus…

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