1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
215–219
Issue
1
Volume
741
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The effects of intranasal infusion of
Publisher
An entity responsible for making the resource available
Brain research
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
1996-11
Subject
The topic of the resource
Male; Animals; Mice; Corpus Striatum/drug effects/*metabolism; Dopamine/metabolism; Olfactory Bulb/drug effects/*metabolism; Norepinephrine/metabolism; Injections; Catecholamines/*metabolism; Dopamine Agents/administration & dosage/*pharmacology; Inbred C57BL; 3; Intraperitoneal; 1-Methyl-4-phenyl-1; 2; Administration; Intranasal; 6-tetrahydropyridine/administration & dosage/*pharmacology
Creator
An entity primarily responsible for making the resource
Dluzen D E; Kefalas G
Description
An account of the resource
Male C57/B1 mice received bilateral intranasal infusions of saline, MPTP or an intraperitoneal injection of MPTP. Infusions were performed using a peristaltic pump at a setting of 100 microliters/min. The MPTP, diluted in saline at concentrations of 2 mg/ml, was infused over 15 (0.1 mg) or 30 (0.2 mg) s, while the saline (control) infusions were of 30 s duration. In a separate group of mice, MPTP was injected via the intraperitoneal route at a dose equivalent to that of the 30-s intranasal concentration (0.2 mg). At 7 days post-treatment, catecholamine concentrations were determined from the olfactory bulbs and corpus striatum. Concentrations of norepinephrine within both the olfactory bulbs and corpus striatum of mice receiving the intranasal infusion of MPTP were significantly lower than those of the intranasal saline and intraperitoneal
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1-Methyl-4-phenyl-1
1996
2
3
6-tetrahydropyridine/administration & dosage/*pharmacology
Administration
Animals
Brain research
Catecholamines/*metabolism
Corpus Striatum/drug effects/*metabolism
Department of Internal Medicine
Dluzen D E
Dopamine Agents/administration & dosage/*pharmacology
Dopamine/metabolism
Inbred C57BL
Injections
Intranasal
Intraperitoneal
Kefalas G
Male
Mice
NEOMED College of Medicine
Norepinephrine/metabolism
Olfactory Bulb/drug effects/*metabolism
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1553-2712.2001.tb02111.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1553-2712.2001.tb02111.x</a>
Pages
337–342
Issue
4
Volume
8
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Intranasal lidocaine for the treatment of migraine headache: a randomized, controlled trial.
Publisher
An entity responsible for making the resource available
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
2001-04
Subject
The topic of the resource
Administration; Adolescent; Adult; Anesthetics; Confidence Intervals; Double-Blind Method; Female; Hospitals; Humans; Intranasal; Lidocaine/*administration & dosage; Local; Male; Middle Aged; Migraine without Aura/diagnosis/*drug therapy; Ohio; Pain Measurement; Patient Satisfaction; Reference Values; Severity of Illness Index; Teaching; Treatment Outcome
Creator
An entity primarily responsible for making the resource
Blanda M; Rench T; Gerson L W; Weigand J V
Description
An account of the resource
OBJECTIVE: To evaluate the effect of intranasal lidocaine for immediate relief (5 minutes) of migraine headache pain. METHODS: A randomized, double-blind, placebo-controlled clinical trial at two university-affiliated community teaching hospitals enrolled patients 18-50 years old with migraine headache as defined by the International Headache Society. Patients who were pregnant, lactating, known to abuse alcohol or drugs, or allergic to one of the study drugs, those who used analgesics within two hours, or those with a first headache were excluded. Statistical significance was assessed by using chi-square or Fisher's exact test for categorical variables and Student's t-test for continuous variables. Patients rated their pain on a 10-centimeter visual analog scale (VAS) prior to drug administration and at 5, 10, 15, 20, and 30 minutes after the initial dose. Medication was either 1 mL of 4% lidocaine or normal saline (placebo) intranasally in split doses 2 minutes apart and intravenous prochlorperazine. Medications were packaged so physicians and patients were unaware of the contents. Successful pain relief was achieved if there was a 50% reduction in pain score or a score below 2.5 cm on the VAS. RESULTS: Twenty-seven patients received lidocaine and 22 placebo. No significant difference was observed between groups in initial pain scores, 8.4 (95% CI = 7.8 to 9.0) lidocaine and 8.6 (95% CI = 8.0 to 9.2) placebo (p = 0.75). Two of 27 patients (7.4%, 95% CI = 0.8, 24.3) in the lidocaine group and three of 22 patients (13.6%, 95% CI = 2.8 to 34.9) in the placebo group had immediate successful pain relief (p = 0.47), with average pain scores of 6.9 (95% CI = 5.9 to 7.8) and 7.0 (95% CI = 5.8 to 8.2), respectively. No difference in pain relief was detected at subsequent measurements. CONCLUSION: There was no evidence that intranasal lidocaine provided rapid relief for migraine headache pain in the emergency department setting.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1553-2712.2001.tb02111.x" target="_blank" rel="noreferrer noopener">10.1111/j.1553-2712.2001.tb02111.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2001
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Administration
Adolescent
Adult
Anesthetics
Blanda M
Confidence Intervals
Department of Emergency Medicine
Double-Blind Method
Female
Gerson L W
Hospitals
Humans
Intranasal
Lidocaine/*administration & dosage
Local
Male
Middle Aged
Migraine without Aura/diagnosis/*drug therapy
NEOMED College of Medicine
Ohio
Pain Measurement
Patient Satisfaction
Reference Values
Rench T
Severity of Illness Index
Teaching
Treatment Outcome
Weigand J V
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/00020840-200306000-00013" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/00020840-200306000-00013</a>
Pages
201–205
Issue
3
Volume
11
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Are nasal steroids safe?
Publisher
An entity responsible for making the resource available
Current opinion in otolaryngology & head and neck surgery
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
2003-06
Subject
The topic of the resource
Administration; Anti-Inflammatory Agents/*administration & dosage/*adverse effects/therapeutic use; Humans; Inhalation; Intranasal; Rhinitis/*drug therapy
Creator
An entity primarily responsible for making the resource
Mehle Mark E
Description
An account of the resource
Nasal steroids have emerged as an integral part of rhinitis management. Most studies have shown no evidence of significant hypothalamic-pituitary-adrenal axis suppression from nasal steroid use, at least based on dynamic testing. Bone mineral density loss, glaucoma, and cataract formation are risks associated with systemic steroids, but reports with nasal steroid use are few. Growth retardation has been seen with some nasal steroids, but not others, based on stadiometric growth studies. Further studies are certainly needed to resolve this issue. Nasal steroids, in general, have an excellent safety record.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/00020840-200306000-00013" target="_blank" rel="noreferrer noopener">10.1097/00020840-200306000-00013</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2003
Administration
Anti-Inflammatory Agents/*administration & dosage/*adverse effects/therapeutic use
Current opinion in otolaryngology & head and neck surgery
Humans
Inhalation
Intranasal
Mehle Mark E
Rhinitis/*drug therapy