1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0361-9230(92)90219-n" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0361-9230(92)90219-n</a>
Pages
967–973
Issue
6
Volume
28
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Attenuation of drinking sweetened water following calcium channel blockade.
Publisher
An entity responsible for making the resource available
Brain research bulletin
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-06
Subject
The topic of the resource
Animals; Calcium Channel Blockers/*pharmacology; Cocaine/pharmacology; Dihydropyridines/pharmacology; Dose-Response Relationship; Drinking Behavior/*drug effects; Drug; Female; Inbred Strains; Injections; Intraventricular; Isradipine; Male; Rats; Reward; Taste/*drug effects
Creator
An entity primarily responsible for making the resource
Calcagnetti D J; Schechter M D
Description
An account of the resource
Recent reports cite results that both cocaine-induced conditioned place preference and activity stimulation are attenuated by pretreatment with the calcium channel blocker isradipine (ISR) in rats. By blocking voltage-dependent
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0361-9230(92)90219-n" target="_blank" rel="noreferrer noopener">10.1016/0361-9230(92)90219-n</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Animals
Brain research bulletin
Calcagnetti D J
Calcium Channel Blockers/*pharmacology
Cocaine/pharmacology
Dihydropyridines/pharmacology
Dose-Response Relationship
Drinking Behavior/*drug effects
Drug
Female
Inbred Strains
Injections
Intraventricular
Isradipine
Male
Rats
Reward
Schechter M D
Taste/*drug effects
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0091-3057(92)90231-4" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0091-3057(92)90231-4</a>
Pages
807–812
Issue
4
Volume
41
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Further evidence for the mechanisms that may mediate nicotine discrimination.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-04
Subject
The topic of the resource
Animals; Calcium Channel Blockers/pharmacology; Dihydropyridines/pharmacology; Discrimination Learning; Dopamine/*metabolism; Dose-Response Relationship; Drug; Inbred Strains; Indoles/pharmacology; Isradipine; Male; Nicotine/administration & dosage/*pharmacology; Rats; Thiazepines/pharmacology; Tropisetron
Creator
An entity primarily responsible for making the resource
Schechter M D; Meehan S M
Description
An account of the resource
Rats were trained to discriminate the interoceptive stimuli produced by subcutaneously administered 0.4 mg/kg nicotine in a two-lever, food-motivated, operant task. Once criterion performance was attained, dose-response experiments indicated an ED50 value of 0.1 mg/kg and subsequent time course experiments showed a maximal effect between 10 and 30 min postadministration with a return to saline-like responding at 2 h. Pretreatment with the presynaptic dopamine release inhibitors CGS 10746B (30 mg/kg), as well as with the dihydropyridine calcium blocker isradipine (15 mg/kg), each produced a significant blockade of nicotine discrimination. In contrast, the 5-hydroxytryptamine (5-HT) receptor 5-HT3 antagonist ICS-205930 did not produce any effect upon nicotine discrimination. Thus, drugs that interfere with calcium influx, viz., isradipine, or with dopamine release (CGS 10746B) also interfere with nicotine discrimination and these results suggest that calcium influx and dopamine release may be necessary conditions for nicotine discrimination.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0091-3057(92)90231-4" target="_blank" rel="noreferrer noopener">10.1016/0091-3057(92)90231-4</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Animals
Calcium Channel Blockers/pharmacology
Dihydropyridines/pharmacology
Discrimination Learning
Dopamine/*metabolism
Dose-Response Relationship
Drug
Inbred Strains
Indoles/pharmacology
Isradipine
Male
Meehan S M
Nicotine/administration & dosage/*pharmacology
Pharmacology, biochemistry, and behavior
Rats
Schechter M D
Thiazepines/pharmacology
Tropisetron
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0091-3057(92)90055-k" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0091-3057(92)90055-k</a>
Pages
37–41
Issue
1
Volume
41
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Effect of altering dopamine or serotonin neurotransmitters upon cathinone discrimination.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-01
Subject
The topic of the resource
Alkaloids/*pharmacology; Animals; Antipsychotic Agents/pharmacology; Calcium Channel Blockers/pharmacology; Dihydropyridines/pharmacology; Discrimination (Psychology)/*drug effects; Discrimination Learning/drug effects; Dopamine/*physiology; Dose-Response Relationship; Drug; Inbred Strains; Isradipine; Male; Neurotransmitter Agents/*physiology; Psychotropic Drugs/*pharmacology; Rats; Serotonin Antagonists/pharmacology; Serotonin/*physiology; Thiazepines/pharmacology; Tropanes/pharmacology
Creator
An entity primarily responsible for making the resource
Schechter M D
Description
An account of the resource
Rats were trained to discriminate between the stimulus properties of 0.8 mg/kg l-cathinone and its vehicle in a two-lever, food-motivated operant task. Once trained, rats showed a dose-related decrease in discriminative performance when tested with lower cathinone doses. An analysis of the dose-response curve indicated an ED50 value of 0.23 mg/kg. Pretreatment with CGS 10746B (5-20 mg/kg) resulted in a dose-related decrease in cathinone discrimination with the highest dose blocking cathinone discrimination. In contrast to the ability of this dopamine release inhibitor to decrease cathinone discrimination, pretreatment with three doses of the calcium channel blocker isradipine (2.5-10 mg/kg) or with the 5-HT3 antagonist MDL 72222 (0.1-0.4 mg/kg) had no effect upon cathinone discrimination. The results suggest that cathinone controls differential responding in a discriminative stimulus task by a mechanism involving presynaptic release of dopamine, which may not be regulated by either neuronal calcium influx through L-type calcium channels or by serotonergic neurons.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0091-3057(92)90055-k" target="_blank" rel="noreferrer noopener">10.1016/0091-3057(92)90055-k</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Alkaloids/*pharmacology
Animals
Antipsychotic Agents/pharmacology
Calcium Channel Blockers/pharmacology
Dihydropyridines/pharmacology
Discrimination (Psychology)/*drug effects
Discrimination Learning/drug effects
Dopamine/*physiology
Dose-Response Relationship
Drug
Inbred Strains
Isradipine
Male
Neurotransmitter Agents/*physiology
Pharmacology, biochemistry, and behavior
Psychotropic Drugs/*pharmacology
Rats
Schechter M D
Serotonin Antagonists/pharmacology
Serotonin/*physiology
Thiazepines/pharmacology
Tropanes/pharmacology