1
40
2
-
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n/a
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Pages
1-1
Volume
27
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Alpha 1-adrenergic Receptor Activation Mimics Ischemic Postconditioning
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Faseb Journal
Date
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2013
2013-04
Subject
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Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
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Janota D M; Yun J
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n/a
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Journal Article or Conference Abstract Publication
2013
Biochemistry & Molecular Biology
Cell Biology
Faseb Journal
Janota D M
Journal Article or Conference Abstract Publication
Life Sciences & Biomedicine - Other
Topics
Yun J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.pharmthera.2017.02.032" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.pharmthera.2017.02.032</a>
Pages
28–34
Volume
175
Dublin Core
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Title
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The versatility and paradox of GDF 11.
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Pharmacology & therapeutics
Date
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2017
2017-07
Subject
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Aging; Aging/metabolism; Animals; Biomarker; Biomarkers/metabolism; BMP signaling; Bone Morphogenetic Proteins/*metabolism; Development; Embryonic Development; Erythropoiesis; Growth differentiation factor 11; Growth Differentiation Factors/*metabolism; Humans; Neurogenesis; Pancreas/growth & development/metabolism; Retina/growth & development/metabolism
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Jamaiyar A; Wan W; Janota D M; Enrick M K; Chilian W M; Yin L
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In addition to its roles in embryonic development, Growth and Differentiation Factor 11 (GDF 11) has recently drawn much interest about its roles in other processes, such as aging. GDF 11 has been shown to play pivotal roles in the rescue of the proliferative and regenerative capabilities of skeletal muscle, neural stem cells and cardiomyocytes. We would be remiss not to point that some controversy exists regarding the role of GDF 11 in biological processes and whether it will serve as a therapeutic agent. The latest studies have shown that the level of circulating GDF 11 correlates with the outcomes of patients with cardiovascular diseases, cancer and uremia. Based on these studies, GDF 11 is a promising candidate to serve as a novel biomarker of diseases. This brief review gives a detailed and concise view of the regulation and functions of GDF 11 and its roles in development, neurogenesis and erythropoiesis as well as the prospect of using this protein as an indicator of cardiac health and aging.
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<a href="http://doi.org/10.1016/j.pharmthera.2017.02.032" target="_blank" rel="noreferrer noopener">10.1016/j.pharmthera.2017.02.032</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Aging
Aging/metabolism
Animals
Biomarker
Biomarkers/metabolism
BMP signaling
Bone Morphogenetic Proteins/*metabolism
Chilian W M
Department of Integrative Medical Sciences
development
Embryonic Development
Enrick M K
Erythropoiesis
Growth differentiation factor 11
Growth Differentiation Factors/*metabolism
Humans
Jamaiyar A
Janota D M
NEOMED College of Medicine
Neurogenesis
Pancreas/growth & development/metabolism
Pharmacology & therapeutics
Retina/growth & development/metabolism
Wan W
Yin L