Spitz nevi in african americans: A retrospective chart review of 11 patients.
African Americans; nevi; nevus; Spitz; Spitzoid
BACKGROUND: Spitz nevi are benign melanocytic neoplasms that typically present as rapidly growing solitary lesions on the head, neck, or lower extremities. Very rare reports have been described in African Americans. METHODS: A single-institution 29-year retrospective review of African American patients diagnosed with Spitz nevi was thoroughly analyzed in order to characterize these rare clinical and histopathologic presentations. RESULTS: Eleven African Americans with spitzoid lesions were identified. Seven (64%) cases were in pediatric patients and nine (82%) were in females. Most lesions were hyperpigmented (73%) and elevated (82%). Six (55%) were compound Spitz nevi, three (27%) were dermal Spitz nevi, and two (18%) were junctional Spitz nevi. Two lesions had more than one atypical feature. Histopathologically, common features were symmetry, sharp circumscription, pagetoid spread (55%) with most being centrally, predominance of epithelioid cells (64%), Kamino bodies (45%), slight pigmentation (46%), maturation of dermal component with depth, and lack of subcutaneous fat involvement or ulceration. Excision was performed on all patients and there were no recurrences although follow-up was limited. CONCLUSION: Awareness of the possibility and various presentations of Spitz nevi in African Americans will help prevent misdiagnosis.
Farid YI;Honda KS
Journal of Cutaneous Pathology
2020
2020-10-16
journalArticle
<a href="http://doi.org/10.1111/cup.13903" target="_blank" rel="noreferrer noopener">10.1111/cup.13903</a>
Diagnoses of hospitalized patients with skin abnormalities prompting biopsy by consulting dermatologists: A 3-year review from a tertiary care center
dermatology hospital consultation; dermatopathology; inpatient dermatology; skin biopsy
BACKGROUND: Dermatologists play an important role in diagnosing and managing hospitalized patients with cutaneous abnormalities. Skin biopsies remain an indispensable tool for aiding dermatologists in accurate diagnosis and treatment. We aimed to determine the range of conditions, and the most common conditions, prompting skin biopsy by dermatology hospital consultation (HCON) services to aid in evaluation of hospitalized patients. METHODS: All hospitalized patients seen by a single tertiary care center dermatology HCON service between 2015 and 2018 who had associated skin biopsies were identified. Histologic features and clinical diagnoses of each patient were classified into 13 histologic reaction pattern categories. RESULTS: Eight hundred and thirty one inpatients evaluated by our dermatology HCON service had 914 skin biopsies. The most frequent diagnostic categories prompting biopsy were vasculopathic (17.6%), interface dermatitis (16.5%), infectious (12.6%), and spongiotic dermatitis (10.9%). The most frequent diagnostic categories included drug reaction (13.2%), leukocytoclastic vasculitis (8.5%), skin cancer (5.4%), graft-vs-host disease (3.5%), connective tissue disease (3.3%), and calciphylaxis (3.0%). CONCLUSION: Our study suggests a variety of serious diseases affecting inpatients prompts biopsy by dermatology consultation services. Educational curricula for dermatology and pathology residents, fellows, and staff designed with these data may enhance knowledge that improves the quality of inpatient dermatology care.
Ellis Ariana; Billings Steven D; Khanna Urmi; Warren Christine B; Piliang Melissa; Vij Alok; Ko Jennifer S; Bergfeld Wilma F; Fernandez Anthony P
Journal of Cutaneous Pathology
2019
2019-12-17
Journal Article
<a href="http://doi.org/10.1111/cup.13628" target="_blank" rel="noreferrer noopener">10.1111/cup.13628</a>
PMID: 31845375
Isolated Benign Primary Cutaneous Plasmacytosis In Two Children
Dermatology; Pathology
Gilliam A; Mostow E; Smith M; Patton D; Rodriguez-Soto J; Mullen R; Oviedo G; Bhatnagar R
Journal of Cutaneous Pathology
2009
2009-01
Journal Article or Conference Abstract Publication
n/a
Metastatic colorectal carcinoma: an unusual presentation.
Aged; Carcinoma; Colorectal Neoplasms/*pathology; Diagnosis; Differential; Humans; Lip Neoplasms/*secondary; Lymphatic Metastasis/pathology; Male; Signet Ring Cell/*secondary; Skin Neoplasms/*secondary; Sweat Gland Neoplasms/pathology
Cutaneous metastases from colorectal carcinomas occur infrequently, usually in the setting of disseminated disease. They most commonly appear on the abdominal wall or perineal area; metastases to other locations of the skin are rare. We describe a case of colorectal signet ring carcinoma with metastasis to the upper lip. To the authors' knowledge, this is the second reported case of colorectal carcinoma with metastasis to the lip and first with signet ring features. Because of the rarity of cutaneous metastases, the primary physician or pathologist may overlook this diagnosis. However, this entity should be considered in the differential diagnosis of adnexal tumors as it may be the initial presentation of the colon carcinoma.
Moonda Afreen; Fatteh Shokat
Journal of cutaneous pathology
2009
2009-01
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1111/j.1600-0560.2008.01007.x" target="_blank" rel="noreferrer noopener">10.1111/j.1600-0560.2008.01007.x</a>