Renal manifestations of tuberous sclerosis complex.
angiomyolipoma; autosomal polycystic kidney disease; renal cystic disease; tuberous sclerosis; Von Hippel–Lindau disease
Tuberous sclerosis complex (TSC) is a genetic condition caused by a mutation in either the TSC1 or TSC2 gene. Disruption of either of these genes leads to impaired production of hamartin or tuberin proteins, leading to the manifestation of skin lesions, tumors, and seizures. TSC can manifest in multiple organ systems with the cutaneous and renal systems being the most commonly affected. These manifestations can secondarily lead to the development of hypertension, chronic kidney disease, and neurocognitive declines. The renal pathologies most commonly seen in TSC are angiomyolipoma, renal cysts, and less commonly, oncocytomas. In this review, we highlight the current understanding on the renal manifestations of TSC along with current diagnosis and treatment guidelines. (Copyright: Nair N et al.)
Nair N;Chakraborty R;Mahajan Z;Sharma A;Sethi SK;Raina R
Journal Of Kidney Cancer And VHL
2020
2020-08-27
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
journalArticle
<a href="http://doi.org/10.15586/jkcvhl.2020.131" target="_blank" rel="noreferrer noopener">10.15586/jkcvhl.2020.131</a>
Contrast-Enhanced Ultrasound-Guided Radiofrequency Ablation of Renal Tumors.
contrast-enhanced ultrasound; radiofrequency ablation; renal tumor ablation; small renal masses; ultrasound contrast agents
Although only limited long-term studies evaluating thermal ablation of renal masses have been performed, it appears that thermal ablation has a comparable
O'Neal Dan; Cohen Tal; Peterson Cynthia; Barr Richard G
Journal of kidney cancer and VHL
2018
1905-07
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.15586/jkcvhl.2018.100" target="_blank" rel="noreferrer noopener">10.15586/jkcvhl.2018.100</a>