1
40
2
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jstrokecerebrovasdis.2015.12.029" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jstrokecerebrovasdis.2015.12.029</a>
Pages
883–893
Issue
4
Volume
25
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Parathyroid Hormone and Subclinical Cerebrovascular Disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study.
Publisher
An entity responsible for making the resource available
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-04
Subject
The topic of the resource
*Magnetic Resonance Imaging; Brain; Brain Diseases; Brain Diseases – Complications; brain MRI; Brain/*diagnostic imaging; cerebrovascular disease; Cerebrovascular Disorders; Cerebrovascular Disorders – Blood; Cerebrovascular Disorders/*blood/*diagnostic imaging; Cohort Studies; Computer Assisted; Computer-Assisted; Cross Sectional Studies; Cross-Sectional Studies; Female; Funding Source; Human; Humans; Image Processing; Leukoencephalopathies/complications/diagnostic imaging; Magnetic Resonance Imaging; Male; Middle Age; Middle Aged; Parathyroid hormone; Parathyroid Hormone/*blood; Parathyroid Hormones – Blood; Prospective Studies; subclinical brain infarcts; white matter hyperintensities
Creator
An entity primarily responsible for making the resource
Korada Sai Krishna C; Zhao Di; Gottesman Rebecca F; Guallar Eliseo; Lutsey Pamela L; Alonso Alvaro; Sharrett A Richey; Post Wendy S; Reis Jared P; Mosley Thomas H; Michos Erin D
Description
An account of the resource
BACKGROUND: Elevated parathyroid hormone (PTH) levels have been associated with cardiovascular disease risk factors and events. We hypothesized that elevated PTH levels would also be associated with subclinical cerebrovascular disease. We examined the relationship between elevated PTH level and white matter hyperintensities (WMHs) and subclinical infarcts measured on brain magnetic resonance imaging (MRI). METHODS: PTH was measured at baseline (1993-1994) among participants free of prior clinical stroke who underwent a brain MRI at baseline (n = 1703) and a second brain MRI 10 years later (n = 948). PTH levels of 65 pg/mL or higher were considered elevated (n = 204). Participants who did not return for a follow-up MRI had, at baseline, higher PTH and a greater prevalence of cardiovascular risk factors (P \textless .05 for all); therefore, multiple imputation was used. The cross-sectional and prospective associations of PTH levels with WMH and MRI-defined infarcts (and their progression) were investigated using multivariable regression models. RESULTS: At baseline, the participants had a mean age of 62 years and were 60% female and 49% black. Cross-sectionally, after adjusting for demographic and lifestyle factors, elevated PTH level was associated with higher WMH score (beta = .19, 95% confidence interval [CI] .04-.35) and increased odds of prevalent infarcts (odds ratio 1.56, 95% CI 1.02-2.36). Results were attenuated after adjustment for potential mediators of this association (i.e., hypertension). No prospective associations were found between PTH and incident infarcts or change in estimated WMH volume, although estimates were imprecise. CONCLUSIONS: Although associated cross-sectionally, we did not confirm any association between elevated PTH level and progression of cerebrovascular changes on brain MRIs obtained 10 years apart. The relationship of PTH with subclinical brain disease warrants further study.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jstrokecerebrovasdis.2015.12.029" target="_blank" rel="noreferrer noopener">10.1016/j.jstrokecerebrovasdis.2015.12.029</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Magnetic Resonance Imaging
2016
Alonso Alvaro
Brain
Brain Diseases
Brain Diseases – Complications
brain MRI
Brain/*diagnostic imaging
cerebrovascular disease
Cerebrovascular Disorders
Cerebrovascular Disorders – Blood
Cerebrovascular Disorders/*blood/*diagnostic imaging
Cohort Studies
Computer Assisted
Computer-Assisted
Cross Sectional Studies
Cross-Sectional Studies
Female
Funding Source
Gottesman Rebecca F
Guallar Eliseo
Human
Humans
Image Processing
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Korada Sai Krishna C
Leukoencephalopathies/complications/diagnostic imaging
Lutsey Pamela L
Magnetic Resonance Imaging
Male
Michos Erin D
Middle Age
Middle Aged
Mosley Thomas H
Parathyroid hormone
Parathyroid Hormone/*blood
Parathyroid Hormones – Blood
Post Wendy S
Prospective Studies
Reis Jared P
Sharrett A Richey
subclinical brain infarcts
white matter hyperintensities
Zhao Di
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.066" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.066</a>
Pages
e48–e49
Issue
3
Volume
27
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Safe Readministration of Intravenous Thrombolysis in Recurrent Basilar Thrombosis.
Publisher
An entity responsible for making the resource available
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-03
Subject
The topic of the resource
Aged; Basilar Artery; Basilar Artery – Drug Effects; Basilar Artery – Physiopathology; Basilar Artery/diagnostic imaging/*drug effects/physiopathology; Cerebral Angiography – Methods; Cerebral Angiography/methods; Computed Tomography Angiography; Drug Administration Schedule; Fibrinolytic Agents – Administration and Dosage; Fibrinolytic Agents – Adverse Effects; Fibrinolytic Agents/*administration & dosage/adverse effects; Humans; Infusions; Intracranial Thrombosis; Intracranial Thrombosis – Drug Therapy; Intracranial Thrombosis – Physiopathology; Intracranial Thrombosis/diagnostic imaging/*drug therapy/physiopathology; Intravenous; Magnetic Resonance Imaging; Male; medication safety; Recombinant Proteins – Administration and Dosage; Recombinant Proteins/administration & dosage; Recurrence; recurrent stroke; Repeat Procedures; Retreatment; thrombolysis; Thrombolytic Therapy – Adverse Effects; Thrombolytic Therapy – Methods; Thrombolytic Therapy/adverse effects/*methods; Thrombosis; Time Factors; Tissue Plasminogen Activator – Administration and Dosage; Tissue Plasminogen Activator – Adverse Effects; Tissue Plasminogen Activator/*administration & dosage/adverse effects; Treatment Outcome; Treatment Outcomes
Creator
An entity primarily responsible for making the resource
Khan Alina; Itrat Ahmed
Description
An account of the resource
We report a patient who had recurrence of stroke in the basilar artery territory because of repeat thrombosis, and was administered intravenous recombinant tissue plasminogen activator (IV-rtPA) twice within a span of 3 weeks without any adverse events, with radiological evidence of successful thrombolysis. Because of minor and improving stroke symptoms with IV-rtPA, endovascular therapy was not performed and there was radiological evidence of recanalization with IV-rtPA alone. This report adds to the very limited literature on the topic demonstrating safe and successful use of repeat IV thrombolysis following a previous recent stroke.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.066" target="_blank" rel="noreferrer noopener">10.1016/j.jstrokecerebrovasdis.2017.09.066</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Aged
Basilar Artery
Basilar Artery – Drug Effects
Basilar Artery – Physiopathology
Basilar Artery/diagnostic imaging/*drug effects/physiopathology
Cerebral Angiography – Methods
Cerebral Angiography/methods
Computed Tomography Angiography
Department of Internal Medicine
Drug Administration Schedule
Fibrinolytic Agents – Administration and Dosage
Fibrinolytic Agents – Adverse Effects
Fibrinolytic Agents/*administration & dosage/adverse effects
Humans
Infusions
Intracranial Thrombosis
Intracranial Thrombosis – Drug Therapy
Intracranial Thrombosis – Physiopathology
Intracranial Thrombosis/diagnostic imaging/*drug therapy/physiopathology
Intravenous
Itrat Ahmed
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Khan Alina
Magnetic Resonance Imaging
Male
medication safety
NEOMED College of Medicine
Recombinant Proteins – Administration and Dosage
Recombinant Proteins/administration & dosage
Recurrence
recurrent stroke
Repeat Procedures
Retreatment
thrombolysis
Thrombolytic Therapy – Adverse Effects
Thrombolytic Therapy – Methods
Thrombolytic Therapy/adverse effects/*methods
Thrombosis
Time Factors
Tissue Plasminogen Activator – Administration and Dosage
Tissue Plasminogen Activator – Adverse Effects
Tissue Plasminogen Activator/*administration & dosage/adverse effects
Treatment Outcome
Treatment Outcomes