Use of the alexandrite laser for treatment of seborrheic keratoses.
Back; Beryllium/*therapeutic use; Humans; Keratosis; Laser Therapy/*methods; Seborrheic/*surgery
BACKGROUND: Seborrheic karatoses are benign lesions that are easily irritated and often cosmetically objectionable. Liquid nitrogen cryotherapy and other surgical methods are useful in treating these lesions, but are difficult to tolerate in patients who have large numbers of lesions requiring treatment. The alexandrite laser was used in one patient to quickly and efficiently destroy hundreds of seborrheic keratoses. The treatment was tolerable and excellent cosmetic results were achieved.
Mehrabi Don; Brodell Robert T
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
2002
2002-05
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1097/00042728-200205000-00017" target="_blank" rel="noreferrer noopener">10.1097/00042728-200205000-00017</a>
Spreading pigmented actinic keratosis: a review.
Actinic/diagnosis/*pathology; Biopsy; Carcinoma; Dermoscopy/methods; Diagnosis; Differential; Disease Progression; Female; Humans; Hutchinson's Melanotic Freckle/diagnosis/*pathology; Immunohistochemistry; Keratosis; Male; Needle; Neoplasm Staging; Precancerous Conditions/*pathology; Risk Assessment; Skin Neoplasms/diagnosis/*pathology; Squamous Cell/diagnosis/*pathology
INTRODUCTION: Spreading pigmented actinic keratosis (SPAK) is a common, but uncommonly reported or appreciated, variant of classic actinic keratosis (AK). It can mimic different pigmented lesions, which may be benign (eg, solar lentigo) or malignant (eg, lentigo maligna). OBJECTIVE: We sought to review current data and identify areas needing further research to establish diagnostic guidelines for SPAK and to increase awareness of this common entity. METHODS: A literature search was performed in both PubMed and MEDLINE databases using the search terms "spreading pigmented actinic keratosis," "pigmented solar keratosis," "pigmented actinic," and "pigmented solar." Each article was retrieved, reviewed, and summarized. RESULTS: SPAK is a rarely reported lesion that can be difficult to distinguish from other benign and malignant pigmented lesions, including seborrheic keratosis, melanoma in situ (lentigo maligna type), and lentigo maligna melanoma. Located mainly on sun-exposed areas and with a size greater than 1.5 cm, the lesion typically spreads laterally. Pathologically, the lesion resembles classic AK with increased basal melanization. The malignancy potential has not yet been elucidated but destructive therapies such as cryotherapy are recommended. LIMITATIONS: Reports not yet published or not included in the comprehensive databases we used may exist that were not analyzed. CONCLUSIONS: SPAK can be associated with adjacent melanoma in situ; therefore, its diagnosis merits increased suspicion for coexisting melanoma.
Uhlenhake Elizabeth E; Sangueza Omar P; Lee Andrew D; Jorizzo Joseph L
Journal of the American Academy of Dermatology
2010
2010-09
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1016/j.jaad.2009.07.026" target="_blank" rel="noreferrer noopener">10.1016/j.jaad.2009.07.026</a>