Chronic mucocutaneous candidiasis associated with malignant thymoma and systemic lupus erythematosus with hypergammaglobulinemia: a case report and literature review.
Adult; Humans; Male; Antifungal Agents/therapeutic use; Itraconazole/therapeutic use; Ketoconazole/therapeutic use; Hypergammaglobulinemia/*complications; Thymoma/*complications; Thymus Neoplasms/*complications; Candidiasis; Lupus Erythematosus; Chronic Mucocutaneous/*complications/drug therapy; Systemic/*complications
Chronic mucocutaneous candidiasis (CMC) is characterized by recurrent candidal infections of the mucous membranes, nails, and skin. Systemic involvement is rare. CMC in adults with coexistent thymoma, benign or malignant, is well-known and is often associated with hypogammaglobulinemia. There is an unusually high frequency of thymoma and systemic lupus erythematosus (SLE). I present a case of a patient with a history of malignant thymoma, SLE, and hypergammaglobulinemia who was found to have CMC. Discussion of the relationship of these findings is presented.
San Filippo James
Cutis
2006
2006-07
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Tinea versicolor of the face in black children in a temperate region.
Humans; Male; Ohio; Child; *African Continental Ancestry Group; *Weather; Clotrimazole/therapeutic use; Facial Dermatoses/drug therapy/etiology/*pathology; Ketoconazole/therapeutic use; Sebum/analysis; Tinea Versicolor/drug therapy/etiology/*pathology; Diagnosis; Differential
Tinea versicolor is a common superficial fungal infection that typically affects young adults in warm, humid climates. We describe two young black children in the temperate northeastern Ohio area with tinea versicolor limited to the face. The occurrence of tinea versicolor on the face is unusual, as is its appearance before puberty. The mycologic and pathophysiologic characteristics of tinea versicolor infection are discussed, and several hypothesis are offered to explain the presence of tinea versicolor in these patients.
Pontasch M J; Kyanko M E; Brodell R T
Cutis
1989
1989-01
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).