VAGINOSONOGRAPHIC MEASUREMENT OF ENDOMETRIAL THICKNESS IN THE EVALUATION OF AMENORRHEA
Reproductive Biology; Obstetrics & Gynecology; ultrasonic assessment
The progestin-induced withdrawal bleeding test has often been used in patients with amenorrhea to assess endogenous estrogen (E) production. The endometrial thickness measured by vaginal ultrasonography with a 5 MHz transducer is also dependent on E stimulation of the endometrium. In this study, 70 consecutive patients were evaluated with both the progestin-induced withdrawal bleeding test and a measurement of the endometrial thickness by vaginosonography. An endometrial thickness of 1.5 mm or less was selected to predict absence of bleeding after a progesterone (P) challenge test. This resulted in a sensitivity of 94% with a 95% confidence interval (CI) of 0.70 to 1.00 and a specificity of 93% with a 95% CI of 0.82 and 0.98. The positive and negative predictive values were 79% and 98%, respectively. This study shows that the endometrial thickness measured by vaginosonography can predict the results of the P challenge test in patients with amenorrhea.
Morcos R N; Leonard M D; Smith M; Bourguet C C; Makii M; Khawli O
Fertility and Sterility
1991
1991-03
Journal Article or Conference Abstract Publication
n/a
Pregnancy-induced hypertension and duration of sexual cohabitation
prevention; hypertension; risk-factors; disease; Obstetrics & Gynecology; cardiovascular; healthy nulliparous women; low-dose aspirin; paternity; pre-eclampsia; pre-eclampsia; pregnancy-induced; sexual cohabitation; pregnancy complications
OBJECTIVE: To evaluate the possible association between duration of sexual cohabitation and the risk of pregnancy-induced hypertension (PIH). STUDY DESIGN: A matched case-control design in which each case of PIH was compared with three controls. Information was obtained about use of barrier contraception, duration of intercourse prior to pregnancy and paternity. RESULTS: Sixty-eight cases were included in the study. For primiparous women, a shorter duration of sexual cohabitation without contraception was associated with a small and nonsignificant risk of PIH. For multiparous women, a greater length of time since stopping use of barrier contraception was associated with a greater risk of PIH. CONCLUSION: Advising nulliparous women to prolong the duration of sexual cohabitation prior to conception in an effort to decrease the risk of PIH is not justified, based on the findings of this study.
Morcos R N; Bourguet C C; Gill P P S; Khawli O; Krew M A; Eucker J; Skarote P
Journal of Reproductive Medicine
2000
2000-03
Journal Article or Conference Abstract Publication
n/a