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40
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Text
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Pages
494–496
Issue
8
Volume
56
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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The effect of renal range dopamine and norepinephrine infusions on the renal vasculature.
Publisher
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The American surgeon
Date
A point or period of time associated with an event in the lifecycle of the resource
1990
1990-08
Subject
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Animals; Dogs; Cardiac Output; Norepinephrine/*pharmacology; Creatine/pharmacokinetics; Dopamine/*pharmacology; Kidney/*drug effects/metabolism; Renal Circulation/*drug effects
Creator
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Strigle T R; Petrinec D
Description
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Renal range dopamine's value was assessed in 15 hypotensive canines using an endotoxin shock model and concurrent pharmacological pressor support. The dogs were prospectively randomized into three treatment groups (fluid resuscitation, fluid and norepinephrine, and fluid, norepinephrine and renal range dopamine). The two groups treated with norepinephrine showed no statistical difference between their pulmonary capillary wedge pressure, systolic blood pressure, and systemic vascular resistance. Cardiac index was slightly increased in the dopamine group (P less than 0.001). Creatinine clearance and renal blood flow were found to have no differences with or without renal range dopamine infusing in either group (P = 0.39 and P = 0.45, respectively). These findings suggest that renal range dopamine is not efficacious with concurrent alpha sympathetic agents for augmentation of renal function or flow in the hypotensive experimental model.
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1990
Animals
Cardiac Output
Creatine/pharmacokinetics
Dogs
Dopamine/*pharmacology
Kidney/*drug effects/metabolism
Norepinephrine/*pharmacology
Petrinec D
Renal Circulation/*drug effects
Strigle T R
The American surgeon