1
40
3
-
Text
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URL Address
<a href="http://doi.org/10.3389/fped.2020.591520" target="_blank" rel="noreferrer noopener">http://doi.org/10.3389/fped.2020.591520</a>
Pages
591520
Volume
8
ISSN
2296-2360
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.3389/fped.2020.591520" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.3389/fped.2020.591520</a>
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Update Year & Number
January 2021 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Pediatrics
Department of Internal Medicine
Affiliated Hospital
Akron Children's Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Acute kidney injury associated with urinary stone disease in children and young adults presenting to a pediatric emergency department.
Publisher
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Frontiers in Pediatrics
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
1905-07
Subject
The topic of the resource
AKI; kidney stones; pediatric; urinary stone disease (USD); urolithiasis
Creator
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Farris N; Raina R; Tibrewal A; Brown M; Colvis M; Schwaderer A; Kusumi K
Description
An account of the resource
Background: Acute kidney injury (AKI) due to urinary stone disease (USD) is rare in adults; AKI rates in children with USD may be higher, and emerging data links stones to chronic kidney disease (CKD) development in adults. Methods: This study is a retrospective analysis of USD patients at a single pediatric hospital system's emergency department (ED). Patients were initially identified by USD ICD codes; USD was then confirmed by imaging or physician documentation; patients had to have baseline creatinine (Cr) and Cr in the ED for comparison to be included. AKI was defined by Kidney Disease: Improving Global Outcomes (KDIGO), Acute Kidney Injury Network (AKIN), and Pediatric Risk, Injury, Failure, Loss, End Stage (pRIFLE). Results: Of the 589 total visits, 264/589 (45%) had data to evaluate for AKI, 23% were AKI(+) and 77% were AKI(-). pRIFLE was most common (82%) and 18% were only positive by AKIN/KDIGO. AKI(+) were more likely to be younger (16.7 vs. 17.4 years, p = 0.046) and more likely to present with vomiting {odds ratio [OR] [95% confidence interval (CI)]: 2.4 [1.4-4.3], p = 0.002}; also, the proportion of AKI(+) was significantly higher in <18 vs. ≥18 years [26.9 vs. 15.5%, p = 0.032, OR (95% CI): 2.0 (1.1-3.9)]. Urinary tract infection (UTI) and obstruction rates were similar between groups. AKI(+) patients had a significant OR <1 suggesting less risk of receiving non-steroidal anti-inflammatory drugs (NSAIDs); however, 51% of them did receive NSAIDs during their ED encounter. AKI(+) patients were more likely to require admission to the hospital (53 vs. 32%, p = 0.001). Conclusion: We have demonstrated a novel association between USD-induced renal colic and AKI in a group of young adults and children. AKI(+) patients were younger and were more likely to present with vomiting. AKI(+) patients did not have higher rates of obstruction or UTI, and 51% of AKI(+) received NSAIDs.
Identifier
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<a href="http://doi.org/10.3389/fped.2020.591520" target="_blank" rel="noreferrer noopener">10.3389/fped.2020.591520</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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journalArticle
2020
AKI
Akron Children's Hospital
Brown M
Colvis M
Department of Internal Medicine
Department of Pediatrics
Farris N
Frontiers in pediatrics
January 2021 List
journalArticle
KIDNEY STONES
Kusumi K
NEOMED College of Medicine
Pediatric
Raina R
Schwaderer A
Tibrewal A
urinary stone disease (USD)
urolithiasis
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/petr.13940" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/petr.13940</a>
Pages
e13940
ISSN
1399-3046 1397-3142
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1111/petr.13940" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1111/petr.13940</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
January 2021 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Pediatrics
Affiliated Hospital
Akron Children's Hopsital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Promoting bone health in children and adolescents following solid organ transplantation.
Publisher
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Pediatric Transplantation
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-12-19
Subject
The topic of the resource
bisphosphonates; bone; calcium; magnesium; metabolic bone disease; phosphorous; physical activity; solid organ transplant; vitamin D
Creator
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Kusumi K; Shaikhkhalil A; Patel HP; Mahan John D
Description
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Solid organ transplantation in children and adolescents provides many benefits through improving critical organ function, including better growth, development, cardiovascular status, and quality of life. Unfortunately, bone status may be adversely affected even when overall status is improving, due to issues with pre-existing bone disease as well as medications and nutritional challenges inherent post-transplantation. For all children and adolescents, bone status entering adulthood is a critical determinant of bone health through adulthood. The overall health and bone status of transplant recipients benefits from attention to regular physical activity, good nutrition, adequate calcium, phosphorous, magnesium and vitamin D intake and avoidance/minimization of soda, extra sodium, and obesity. Many immunosuppressive agents, especially glucocorticoids, can adversely affect bone function and development. Minimizing exposure to "bone-toxic" medications is an important part of promoting bone health in children post-transplantation. Existing guidelines detail how regular monitoring of bone status and biochemical markers can help detect bone abnormalities early and facilitate valuable bone-directed interventions. Attention to calcium and vitamin D supplementation, as well as tapering and withdrawing glucocorticoids as early as possible after transplant, can provide best bone outcomes for these children. Dual-energy X-ray absorptiometry can be useful to detect abnormal bone mass and fracture risk in this population and newer bone assessment methods are being evaluated in children at risk for poor bone outcomes. Newer bone therapies being explored in adults with transplants, particularly bisphosphonates and the RANKL inhibitor denosumab, may offer promise for children with low bone mass post-transplantation.
Identifier
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<a href="http://doi.org/10.1111/petr.13940" target="_blank" rel="noreferrer noopener">10.1111/petr.13940</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2020
Akron Children's Hospital
bisphosphonates
Bone
calcium
Department of Pediatrics
January 2021 List
journalArticle
Kusumi K
Magnesium
Mahan John D
METABOLIC BONE DISEASE
NEOMED College of Medicine
Patel HP
Pediatric Transplantation
phosphorous
Physical Activity
Shaikhkhalil A
Solid organ transplant
Vitamin D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/jch.13905" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/jch.13905</a>
Pages
1059–1069
Issue
6
Volume
22
Search for Full-text
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1111/jch.13905" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1111/jch.13905</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
July 2020 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Association of pulse pressure, pulse pressure index, and ambulatory arterial stiffness index with kidney function in a cross-sectional pediatric chronic kidney disease cohort from the CKiD study.
Publisher
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Journal of Clinical Hypertension
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-06
Subject
The topic of the resource
inflammation; risk; children; blood-pressure; progression; ckd; AASI; chronic kidney disease; pulse pressure; pulse pressure index; aasi; albuminuria; dialysis patients; left-ventricular hypertrophy
Creator
An entity primarily responsible for making the resource
Raina R; Polaconda S; Nair N; Chakraborty R; Sethi S; Krishnappa V; Kapur G; Mhanna M; Kusumi K
Description
An account of the resource
The morbidity and mortality of adult and pediatric chronic kidney disease (CKD) and end-stage renal disease (ESRD) populations are mainly driven by cardiovascular disease (CVD). Improving CVD outcomes focuses on risk assessment of factors including diastolic blood pressure (DBP), systolic blood pressure (SBP), left ventricular mass index (LVMI), pulse pressure (PP), and pulse pressure index (PPi), which is calculated as PP/SBP. These markers are also proven predictors of CKD progression; however, their role in children has not been established. This study aims to evaluate the relationship between PP, PPi, ambulatory arterial stiffness index (AASI), and proteinuria with kidney function in pediatric CKD patients; it is a retrospective analysis of 620 patients (1-16 years) from the NIDDK Chronic Kidney Disease in Children (CKiD) registry. The authors analyzed data for three separate cohorts: an overall CKD as well as immunological versus non-immunological cause for CKD groups. An inverse relationship was found between SBP, DBP, and PP with iGFR and LVMI in the overall CKD group. Our immunological CKD subgroup showed significantly higher serum creatinine, SBP, DBP, and PP values with significantly lower serum albumin levels compared to the non-immunological group. There were no significant differences with iohexol-based glomerular filtration rate (iGFR), LVMI, PPi, or high-sensitivity C-reactive protein (hs-CRP) between the two groups. A subgroup analysis demonstrated that SBP, DBP, and PP all correlated significantly with LVMI in the immunological CKD patients but not the non-immunological subgroup. Additionally, AASI data in the overall CKD population were significantly correlated with PP, PPi, and DBP. This study is one of the first to correlate noninvasive measurements of vascular compliance including PP, PPi, and AASI with iGFR and LVMI in a pediatric CKD cohort. Improving our understanding of surrogate markers for early CVD is integral to improving the care of pediatric CKD population as these patients have yet to develop the hard end points of ESRD, heart failure, myocardial infarction, or stroke.
Identifier
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<a href="http://doi.org/10.1111/jch.13905" target="_blank" rel="noreferrer noopener">10.1111/jch.13905</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2020
AASI
albuminuria
blood-pressure
Chakraborty R
Children
Chronic kidney disease
ckd
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
Dialysis Patients
Inflammation
Journal of Clinical Hypertension
journalArticle
July 2020 List
Kapur G
Krishnappa V
Kusumi K
left-ventricular hypertrophy
Mhanna M
Nair N
NEOMED College of Medicine
Polaconda S
progression
pulse pressure
pulse pressure index
Raina R
Risk
Sethi S