1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.taap.2018.09.011" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.taap.2018.09.011</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
102-107
Volume
359
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.
Publisher
An entity responsible for making the resource available
Toxicology and applied pharmacology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-11
Subject
The topic of the resource
Humans; Reactive Oxygen Species/metabolism; Oxidation-Reduction; Liver; *Reactive oxygen species; Kinetics; Recombinant Proteins/metabolism; Oxygen Consumption; Free Radicals/metabolism; Microsomes; *Cytochrome b5; *Free radicals; *Redox cycling; Benzoquinones/*metabolism; Cytochrome-B(5) Reductase/*metabolism; NADP/metabolism; Nitrofurantoin/*metabolism
Creator
An entity primarily responsible for making the resource
Szilagyi John T; Fussell Karma C; Wang Yun; Jan Yi-Hua; Mishin Vladimir; Richardson Jason R; Heck Diane E; Yang Shaojun; Aleksunes Lauren M; Laskin Debra L; Laskin Jeffrey D
Description
An account of the resource
NADH cytochrome b5 reductase mediates electron transfer from NADH to cytochrome b5 utilizing flavin adenine dinucleotide as a redox cofactor. Reduced cytochrome b5 is an important cofactor in many metabolic reactions including cytochrome
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.taap.2018.09.011" target="_blank" rel="noreferrer noopener">10.1016/j.taap.2018.09.011</a>
*Cytochrome b5
*Free radicals
*Reactive oxygen species
*redox cycling
2018
Aleksunes Lauren M
Benzoquinones/*metabolism
Cytochrome-B(5) Reductase/*metabolism
Free Radicals/metabolism
Fussell Karma C
Heck Diane E
Humans
Jan Yi-Hua
Kinetics
Laskin Debra L
Laskin Jeffrey D
Liver
Microsomes
Mishin Vladimir
NADP/metabolism
Nitrofurantoin/*metabolism
Oxidation-Reduction
Oxygen Consumption
Reactive Oxygen Species/metabolism
Recombinant Proteins/metabolism
Richardson Jason R
Szilagyi John T
Toxicology and applied pharmacology
Wang Yun
Yang Shaojun
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/nyas.13156" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/nyas.13156</a>
Pages
80–86
Issue
1
Volume
1378
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Novel approaches to mitigating parathion toxicity: targeting cytochrome
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-08
Subject
The topic of the resource
*menadione; *organophosphorus pesticides; *paraoxon; *parathion; *redox cycling; Animals; Cholinesterase Inhibitors/metabolism/*toxicity; Cytochrome P-450 Enzyme Inhibitors/*administration & dosage/metabolism; Cytochrome P-450 Enzyme System/metabolism; Drug Delivery Systems/*methods; Humans; Insecticides/metabolism/toxicity; Organophosphate Poisoning/drug therapy/enzymology; Parathion/metabolism/*toxicity; Vitamin K 3/*administration & dosage/metabolism
Creator
An entity primarily responsible for making the resource
Jan Yi-Hua; Richardson Jason R; Baker Angela A; Mishin Vladimir; Heck Diane E; Laskin Debra L; Laskin Jeffrey D
Description
An account of the resource
Accidental or intentional exposures to parathion, an organophosphorus (OP) pesticide, can cause severe poisoning in humans. Parathion toxicity is dependent on its metabolism by the cytochrome P450 (CYP) system to paraoxon (diethyl
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/nyas.13156" target="_blank" rel="noreferrer noopener">10.1111/nyas.13156</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*menadione
*organophosphorus pesticides
*paraoxon
*parathion
*redox cycling
2016
Animals
Annals of the New York Academy of Sciences
Baker Angela A
Cholinesterase Inhibitors/metabolism/*toxicity
Cytochrome P-450 Enzyme Inhibitors/*administration & dosage/metabolism
Cytochrome P-450 Enzyme System/metabolism
Department of Pharmaceutical Sciences
Drug Delivery Systems/*methods
Heck Diane E
Humans
Insecticides/metabolism/toxicity
Jan Yi-Hua
Laskin Debra L
Laskin Jeffrey D
Mishin Vladimir
NEOMED College of Pharmacy
Organophosphate Poisoning/drug therapy/enzymology
Parathion/metabolism/*toxicity
Richardson Jason R
Vitamin K 3/*administration & dosage/metabolism
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/toxsci/kfw031" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/toxsci/kfw031</a>
Pages
150–159
Issue
1
Volume
151
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.
Publisher
An entity responsible for making the resource available
Toxicological sciences : an official journal of the Society of Toxicology
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-05
Subject
The topic of the resource
*cytochrome P450; *flavoenzymes; *heme; *nitric oxide synthase; *reactive oxygen species; Animals; Cytochrome P-450 Enzyme Inhibitors/*pharmacology; Cytochrome P-450 Enzyme System/*metabolism; Dose-Response Relationship; Drug; Heme/*antagonists & inhibitors/metabolism; Humans; Liver/drug effects/enzymology; Mice; Microsomes; Nitric Oxide Synthase Type II/*antagonists & inhibitors/metabolism; Nitric Oxide/metabolism; Onium Compounds/*pharmacology; Rats; Recombinant Proteins/metabolism; Sprague-Dawley; Time Factors
Creator
An entity primarily responsible for making the resource
Szilagyi John T; Mishin Vladimir; Heck Diane E; Jan Yi-Hua; Aleksunes Lauren M; Richardson Jason R; Heindel Ned D; Laskin Debra L; Laskin Jeffrey D
Description
An account of the resource
Cytochrome P450 (CYP) enzymes mediate mixed-function oxidation reactions important in drug metabolism. The aromatic heterocyclic cation, diphenyleneiodonium (DPI), binds flavin in cytochrome P450 reductase and inhibits
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1093/toxsci/kfw031" target="_blank" rel="noreferrer noopener">10.1093/toxsci/kfw031</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*cytochrome P450
*flavoenzymes
*heme
*nitric oxide synthase
*Reactive oxygen species
2016
Aleksunes Lauren M
Animals
Cytochrome P-450 Enzyme Inhibitors/*pharmacology
Cytochrome P-450 Enzyme System/*metabolism
Department of Pharmaceutical Sciences
Dose-Response Relationship
Drug
Heck Diane E
Heindel Ned D
Heme/*antagonists & inhibitors/metabolism
Humans
Jan Yi-Hua
Laskin Debra L
Laskin Jeffrey D
Liver/drug effects/enzymology
Mice
Microsomes
Mishin Vladimir
NEOMED College of Pharmacy
Nitric Oxide Synthase Type II/*antagonists & inhibitors/metabolism
Nitric Oxide/metabolism
Onium Compounds/*pharmacology
Rats
Recombinant Proteins/metabolism
Richardson Jason R
Sprague-Dawley
Szilagyi John T
Time Factors
Toxicological sciences : an official journal of the Society of Toxicology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.taap.2018.09.011" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.taap.2018.09.011</a>
Pages
102–107
Volume
359
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.
Publisher
An entity responsible for making the resource available
Toxicology and applied pharmacology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-11
Subject
The topic of the resource
Cytochrome b5; Free radicals; Reactive oxygen species; Redox cycling
Creator
An entity primarily responsible for making the resource
Szilagyi John T; Fussell Karma C; Wang Yun; Jan Yi-Hua; Mishin Vladimir; Richardson Jason R; Heck Diane E; Yang Shaojun; Aleksunes Lauren M; Laskin Debra L; Laskin Jeffrey D
Description
An account of the resource
NADH cytochrome b5 reductase mediates electron transfer from NADH to cytochrome b5 utilizing flavin adenine dinucleotide as a redox cofactor. Reduced cytochrome b5 is an important cofactor in many metabolic reactions including cytochrome
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.taap.2018.09.011" target="_blank" rel="noreferrer noopener">10.1016/j.taap.2018.09.011</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Aleksunes Lauren M
Cytochrome b5
Department of Pharmaceutical Sciences
Free radicals
Fussell Karma C
Heck Diane E
Jan Yi-Hua
Laskin Debra L
Laskin Jeffrey D
Mishin Vladimir
NEOMED College of Pharmacy
reactive oxygen species
Redox cycling
Richardson Jason R
Szilagyi John T
Toxicology and applied pharmacology
Wang Yun
Yang Shaojun