1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
267–275
Issue
5
Volume
112
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Cardiac computed tomographic angiography and the primary care physician.
Publisher
An entity responsible for making the resource available
The Journal of the American Osteopathic Association
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-05
Subject
The topic of the resource
Adult; Female; Humans; Male; Middle Aged; Aged; Risk Assessment/methods; Primary Health Care/*methods; Chest Pain/diagnosis/etiology; Coronary Artery Disease/*diagnosis/pathology; Coronary Vessels/*pathology; Stroke Volume; Tomography; *Physicians; Ventricular Function; Left; Primary Care; X-Ray Computed/*instrumentation
Creator
An entity primarily responsible for making the resource
Mikolich J Ronald
Description
An account of the resource
Through advancements in computer processing speed and storage capacity, new cardiac imaging modalities have become clinically feasible and useful. Cardiac computed tomographic angiography, a new diagnostic imaging modality, is capable of assessing coronary artery disease and left ventricular function on a par with invasive coronary arteriography in selected patients who meet appropriate use criteria. This imaging modality is of clinical value in the assessment of patients with chest pain who have an intermediate risk of coronary atherosclerosis. The purpose of the present report is to educate primary care physicians about the basic principles of advanced cardiac imaging techniques and to convey a useful strategy for their appropriate use in the current environment of medical economics.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Physicians
2012
Adult
Aged
Chest Pain/diagnosis/etiology
Coronary Artery Disease/*diagnosis/pathology
Coronary Vessels/*pathology
Department of Internal Medicine
Female
Humans
Left
Male
Middle Aged
Mikolich J Ronald
NEOMED College of Medicine
primary care
Primary Health Care/*methods
Risk Assessment/methods
Stroke Volume
The Journal of the American Osteopathic Association
Tomography
Ventricular Function
X-Ray Computed/*instrumentation
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/jappl.1994.77.3.1155" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/jappl.1994.77.3.1155</a>
Pages
1155–1163
Issue
3
Volume
77
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Edema development and recovery in neurogenic pulmonary edema.
Publisher
An entity responsible for making the resource available
Journal of applied physiology (Bethesda, Md. : 1985)
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
1994-09
Subject
The topic of the resource
Animals; Atrial Function; Blood Gas Analysis; Blood Volume; Dogs; Extravascular Lung Water/drug effects/*physiology; Female; Hemodynamics; Left; Male; Pulmonary Artery/physiopathology; Pulmonary Circulation/drug effects/physiology; Pulmonary Edema/chemically induced/*physiopathology; Radio-Iodinated; Serum Albumin; Sympathetic Nervous System/physiopathology
Creator
An entity primarily responsible for making the resource
Maron M B; Holcomb P H; Dawson C A; Rickaby D A; Clough A V; Linehan J H
Description
An account of the resource
We determined the time course of changes in extravascular lung water (EVLW) that occur after massive sympathetic activation produced by intracisternal veratrine administration in chloralose-anesthetized dogs. Three groups of dogs were studied. In the first group (n = 9), acute increases in EVLW (occurring within minutes) were determined both by measuring extravascular thermal volume and by gravimetric analysis. In the second (n = 6) and third (n = 7) groups, changes in EVLW were followed for 2-3 h after veratrine administration. Extravascular thermal volume was measured in the second group. In the third group, right atrial injections of a vascular indicator (125I-labeled serum albumin) and an extravascular indicator (3HOH) were made while blood was sampled from the pulmonary artery (PA) and left atrium, and EVLW was determined by deconvolution of the left atrial and PA concentration-time curves. Indicator-dilution and gravimetric EVLW increased acutely only in dogs in which PA pressure exceeded 60 Torr, with two- to four-fold increases in EVLW being observed in dogs that developed the highest PA pressures (maximum 94 Torr). Thus, severe edema can develop rapidly after massive sympathetic nervous system activation but requires extreme degrees of pulmonary hypertension. In several dogs after the acute increase in EVLW associated with the pulmonary hypertension, the indicator-dilution EVLW decreased with time. These decreases appear to effect clearance of edema fluid rather than alterations in perfusion.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/jappl.1994.77.3.1155" target="_blank" rel="noreferrer noopener">10.1152/jappl.1994.77.3.1155</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1994
Animals
Atrial Function
Blood Gas Analysis
Blood Volume
Clough A V
Dawson C A
Dogs
Extravascular Lung Water/drug effects/*physiology
Female
Hemodynamics
Holcomb P H
Journal of applied physiology (Bethesda, Md. : 1985)
Left
Linehan J H
Male
Maron M B
Pulmonary Artery/physiopathology
Pulmonary Circulation/drug effects/physiology
Pulmonary Edema/chemically induced/*physiopathology
Radio-Iodinated
Rickaby D A
Serum Albumin
Sympathetic Nervous System/physiopathology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.1992.263.3.H784" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.1992.263.3.H784</a>
Pages
H784–791
Issue
3
Volume
263
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Factors involved in left ventricular dysfunction after massive sympathetic activation.
Publisher
An entity responsible for making the resource available
The American journal of physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-09
Subject
The topic of the resource
*Ventricular Function; Animals; Blood Pressure/drug effects/physiology; Catecholamines/physiology; Female; Heart Conduction System/*physiology; Heart Diseases/*physiopathology; Heart Rate/drug effects; In Vitro Techniques; Left; Male; Rabbits; Sympathetic Nervous System/drug effects/*physiology; Veratrine/pharmacology
Creator
An entity primarily responsible for making the resource
Pilati C F; Bosso F J; Maron M B
Description
An account of the resource
We sought to determine whether catecholamines are responsible for the depressed left ventricular (LV) function that follows massive sympathetic nervous system (SNS) activation and whether the additional myocardial energy demands of
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajpheart.1992.263.3.H784" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.1992.263.3.H784</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Ventricular Function
1992
Animals
Blood Pressure/drug effects/physiology
Bosso F J
Catecholamines/physiology
Female
Heart Conduction System/*physiology
Heart Diseases/*physiopathology
Heart Rate/drug effects
In Vitro Techniques
Left
Male
Maron M B
Pilati C F
Rabbits
Sympathetic Nervous System/drug effects/*physiology
The American journal of physiology
Veratrine/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s11655-016-2621-z" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s11655-016-2621-z</a>
Pages
40–47
Issue
1
Volume
23
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Salvianolate reduces murine myocardial ischemia and reperfusion injury via ERK1/2 signaling pathways in vivo.
Publisher
An entity responsible for making the resource available
Chinese journal of integrative medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-01
Subject
The topic of the resource
*MAP Kinase Signaling System/drug effects; Animal Studies; Animals; Blotting; Cardiotonic Agents/pharmacology/therapeutic use; Chinese medicine; Descriptive Statistics; extracellular signal-regulated kinase 1/2; Flavonoids/pharmacology; Heart Ventricle; Heart Ventricles/drug effects/pathology; In Vivo Studies; Inbred C57BL; ischemia and reperfusion injury; Left; Male; Mice; Mitogen-Activated Protein Kinase 1/*metabolism; Mitogen-Activated Protein Kinase 3/*metabolism; Molecular Structure; Myocardial Ischemia – Drug Therapy; Myocardial Reperfusion Injury – Drug Therapy; Myocardial Reperfusion Injury/*drug therapy/enzymology/pathology; Organ Size/drug effects; P-Value; Phosphorylation; Phosphorylation/drug effects; Plant Extracts – Administration and Dosage; Plant Extracts/chemistry/pharmacology/*therapeutic use; protein kinase B; Protein Kinase Inhibitors – Administration and Dosage; Protein Kinase Inhibitors/pharmacology; Protein Kinases – Analysis; Protein Kinases – Drug Effects; salvianolate; Signal Transduction; Staining and Labeling; Western
Creator
An entity primarily responsible for making the resource
Qi Jianyong; Yu Juan; Huang Dong-Hui; Guo Liheng; Wang Lei; Huang Xin; Huang Hai-Ding; Zhou Miao; Zhang Minzhou; Wu Jiashin
Description
An account of the resource
OBJECTIVE: To analyze the effects of salvianolate on myocardial infarction in a murine in vivo model of ischemia and reperfusion (I/R) injury. METHODS: Myocardial I/R injury model was constructed in mice by 30 min of coronary occlusion followed by 24 h of reperfusion and pretreated with salvianolate 30 min before I/R (SAL group). The SAL group was compared with SHAM (no I/R and no salvianolate), I/R (no salvianolate), and ischemia preconditioning (IPC) groups. Furthermore, an ERK1/2 inhibitor PD98059 (1 mg/kg), and a phosphatidylinositol-3-kinase (PI3-K) inhibitor, LY294002 (7.5 mg/kg), were administered intraperitoneal injection (i.p) for 30 min prior to salvianolate, followed by I/R surgery in LY and PD groups. By using a double staining method, the ratio of the infarct size (IS) to left ventricle (LV) and of risk region (RR) to LV were compared among the groups. Correlations between IS and RR were analyzed. Western-blot was used to detect the extracellular signal-regulated kinase 1/2 (ERK1/2) and protein kinase B (AKT) phosphorylation changes. RESULTS: There were no significant differences between RR to LV ratio among the SHAM, I/R, IPC and SAL groups (P\textgreater0.05). The SAL and IPC groups had IS of 26.1%+/-1.4% and 22.3%+/-2.9% of RR, respectively, both of which were significantly smaller than the I/R group (38.5%+/-2.9% of RR, P\textless0.05, P\textless0.01, respectively). Moreover, the phosphorylation of ERK1/2 was increased in SAL group (P\textless0.05), while AKT had no significant change. LY294002 further reduced IS, whereas the protective role of salvianolate could be attenuated by PD98059, which increased the IS. Additionally, the IS was not linearly related to the RR (r=0.23, 0.45, 0.62, 0.17, and 0.52 in the SHAM, I/R, SAL, LY and PD groups, respectively). CONCLUSION: Salvianolate could reduce myocardial I/R injury in mice in vivo, which involves an ERK1/2 pathway, but not a PI3-K signaling pathway.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s11655-016-2621-z" target="_blank" rel="noreferrer noopener">10.1007/s11655-016-2621-z</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*MAP Kinase Signaling System/drug effects
2017
Animal Studies
Animals
Blotting
Cardiotonic Agents/pharmacology/therapeutic use
Chinese journal of integrative medicine
Chinese medicine
Descriptive Statistics
extracellular signal-regulated kinase 1/2
Flavonoids/pharmacology
Guo Liheng
Heart Ventricle
Heart Ventricles/drug effects/pathology
Huang Dong-Hui
Huang Hai-Ding
Huang Xin
In Vivo Studies
Inbred C57BL
ischemia and reperfusion injury
Left
Male
Mice
Mitogen-Activated Protein Kinase 1/*metabolism
Mitogen-Activated Protein Kinase 3/*metabolism
Molecular Structure
Myocardial Ischemia – Drug Therapy
Myocardial Reperfusion Injury – Drug Therapy
Myocardial Reperfusion Injury/*drug therapy/enzymology/pathology
Organ Size/drug effects
P-Value
Phosphorylation
Phosphorylation/drug effects
Plant Extracts – Administration and Dosage
Plant Extracts/chemistry/pharmacology/*therapeutic use
protein kinase B
Protein Kinase Inhibitors – Administration and Dosage
Protein Kinase Inhibitors/pharmacology
Protein Kinases – Analysis
Protein Kinases – Drug Effects
Qi Jianyong
salvianolate
Signal Transduction
Staining and Labeling
Wang Lei
Western
Wu Jiashin
Yu Juan
Zhang Minzhou
Zhou Miao