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40
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Text
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n/a
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Pages
543-546
Issue
3
Volume
55
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Title
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VAGINOSONOGRAPHIC MEASUREMENT OF ENDOMETRIAL THICKNESS IN THE EVALUATION OF AMENORRHEA
Publisher
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Fertility and Sterility
Date
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1991
1991-03
Subject
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Reproductive Biology; Obstetrics & Gynecology; ultrasonic assessment
Creator
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Morcos R N; Leonard M D; Smith M; Bourguet C C; Makii M; Khawli O
Description
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The progestin-induced withdrawal bleeding test has often been used in patients with amenorrhea to assess endogenous estrogen (E) production. The endometrial thickness measured by vaginal ultrasonography with a 5 MHz transducer is also dependent on E stimulation of the endometrium. In this study, 70 consecutive patients were evaluated with both the progestin-induced withdrawal bleeding test and a measurement of the endometrial thickness by vaginosonography. An endometrial thickness of 1.5 mm or less was selected to predict absence of bleeding after a progesterone (P) challenge test. This resulted in a sensitivity of 94% with a 95% confidence interval (CI) of 0.70 to 1.00 and a specificity of 93% with a 95% CI of 0.82 and 0.98. The positive and negative predictive values were 79% and 98%, respectively. This study shows that the endometrial thickness measured by vaginosonography can predict the results of the P challenge test in patients with amenorrhea.
Identifier
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n/a
Format
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Journal Article or Conference Abstract Publication
1991
Bourguet C C
Department of Family & Community Medicine
Fertility and Sterility
Journal Article or Conference Abstract Publication
Khawli O
Leonard M D
Makii M
Morcos R N
NEOMED College of Medicine
Obstetrics & Gynecology
Reproductive Biology
Smith M
ultrasonic assessment