Cocaine use by pregnant women is currently of concern for its social and economic impact. Clinical studies of cocaine exposed offspring are limited by methodological constraints. In this study we used a rabbit model to examine the effects of…
Cocaine increases the synaptic concentration of neurotransmitters by inhibiting catecholamine transporters. Disturbances of behavior and cellular physiology have been associated with prenatal cocaine exposure and are related to changes in dopamine…
Prenatal cocaine exposure results in several documented changes in neurotransmitter receptor number and structure. Increases have been reported for cortical catecholamine and indoleamine receptor number and binding affinity, in the subunit expression…
