Long-term potentiation is an enduring increase in synaptic efficacy following repeated stimulation of afferent fibers that is thought to underlie memory. In area CA1 of the hippocampus at least two forms of synaptic potentiation coexist at the same…
The two forms of long-term potentiation (LTP) and one form of long-term depression (LTD) in hippocampal area CA1 are induced by different afferent tetani: LTD is induced by a 3- to 5-Hz tetanus, whereas higher frequencies are necessary for LTP…