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Text
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<a href="http://doi.org/10.1016/j.dib.2017.03.054" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.dib.2017.03.054</a>
Pages
150–155
Volume
12
Dublin Core
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Title
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Dataset of effect of Wogonin, a natural flavonoid, on the viability and activation of NF-kappaB and MAPKs in IL-1beta-stimulated human OA chondrocytes.
Publisher
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Data in brief
Date
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2017
2017-06
Subject
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MAPK; Mass-spectrometry; NF-kappaB; Nrf2; Osteoarthritis; Wogonin
Creator
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Khan Nazir M; Haseeb Abdul; Ansari Mohammad Y; Devarapalli Pratap; Haynie Sara; Haqqi Tariq M
Description
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This article contains data related to the article "Wogonin, a plant derived small molecule exerts potent anti-inflammatory and chondroprotective effects through activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes" (Khan et al. 2017) [1]. The data are related to effects of Wogonin on the viability and IL-1beta-stimulated activation of NF-kappaB and ERK1/2, JNK1/2 and p38 MAPKs in human OA chondrocytes. Gene expression data representing the chondrogenic phenotype and the efficiency of Nrf2 knockdown in monolayer culture of human OA chondrocytes were shown. Moreover, mass spectrometric calibration curve of Wogonin used to quantify the intracellular uptake were also presented. The data are presented in the form of figures and significance of these has been given in the research article (Khan et al. 2017) [1].
Identifier
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<a href="http://doi.org/10.1016/j.dib.2017.03.054" target="_blank" rel="noreferrer noopener">10.1016/j.dib.2017.03.054</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Ansari Mohammad Y
Data in brief
Department of Anatomy & Neurobiology
Devarapalli Pratap
Haqqi Tariq M
Haseeb Abdul
Haynie Sara
Khan Nazir M
MAPK
Mass-spectrometry
NEOMED College of Medicine
NF-kappaB
Nrf2
Osteoarthritis
Wogonin