1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/hipo.20048" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/hipo.20048</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
246-253
Issue
2
Volume
15
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
BDNF protects against stress-induced impairments in spatial learning and memory and UP
Publisher
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Hippocampus
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
2005
Subject
The topic of the resource
adult-rat; brain; central-nervous-system; hippocampal pyramidal neurons; hippocampus; in-vivo; knockout mice; long-term potentiation; neuroprotection; Neurosciences & Neurology; neurotrophic factor; neurotrophins; rat; synaptic plasticity; synaptic transmission
Creator
An entity primarily responsible for making the resource
Radecki D T; Brown L M; Martinez J; Teyler T J
Description
An account of the resource
The present study investigated whether infusion of brain-derived neurotrophic factor (BDNF) could ameliorate stress-induced impairments in spatial learning and memory as well as hippocampal long-term potentiation (LTP) of rats. Chronic immobilization stress (2 h/day X 7 days) significantly impaired spatial performance in the Morris water maze, elevated plasma corticosterone, and attenuated LTP in hippocampal slices from these animals as compared with normal control subjects. BDNF was infused into the left hippocampus (0.5 mu l/h) for 14 days, beginning 7 days before the stress exposure. The BDNF group was protected from the deleterious effects of stress and performed at a level indistinguishable from normal control animals despite the presence of elevated corticosterone. BDNF alone and sham infusions had no effect on performance or LTP. These results demonstrate that spatial learning and memory, and LTP, a candidate neural substrate of learning and memory, are compromised during chronic stress, and may be protected by BDNF administration. (c) 2004 Wiley-Liss, Inc.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/hipo.20048" target="_blank" rel="noreferrer noopener">10.1002/hipo.20048</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2005
adult-rat
Brain
Brown L M
central-nervous-system
hippocampal pyramidal neurons
Hippocampus
in-vivo
Journal Article
knockout mice
Long-Term Potentiation
Martinez J
Neuroprotection
Neurosciences & Neurology
neurotrophic factor
neurotrophins
Radecki D T
rat
synaptic plasticity
Synaptic Transmission
Teyler T J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1086/432063" target="_blank" rel="noreferrer noopener">http://doi.org/10.1086/432063</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
554-556
Issue
4
Volume
41
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
HIV infection does not influence clinical outcomes in hospitalized patients with bacterial community-acquired pneumonia: Results from the CAPO International Cohort Study
Publisher
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Clinical Infectious Diseases
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
2005-08
Subject
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therapy; Infectious Diseases; Microbiology; Immunology
Creator
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Christensen D; Feldman C; Rossi P; Marrie T; Blasi F; Luna C; Fernandez P; Porras J; Martinez J; Weiss K; Levy G; Lode H; Gross P; File T; Invest Capo
Description
An account of the resource
In a case-control study, outcomes for 58 human immunodeficiency virus (HIV)-positive patients with community-acquired pneumonia ( CAP) were compared with outcomes for 174 HIV-negative patients with CAP. No differences were found in the time to clinical stability, the length of hospitalization, and mortality. Clinical outcomes for hospitalized patients with CAP may not be influenced by HIV infection.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1086/432063" target="_blank" rel="noreferrer noopener">10.1086/432063</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2005
Blasi F
Christensen D
Clinical Infectious Diseases
Feldman C
Fernandez P
File T
Gross P
Immunology
Infectious Diseases
Invest Capo
Journal Article or Conference Abstract Publication
Levy G
Lode H
Luna C
Marrie T
Martinez J
Microbiology
Porras J
Rossi P
therapy
Weiss K