1
40
12
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jmbbm.2013.01.025" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jmbbm.2013.01.025</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
47-56
Volume
21
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Dublin Core
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Title
A name given to the resource
New Biomaterial As A Promising Alternative To Silicone Breast Implants
Publisher
An entity responsible for making the resource available
Journal of the Mechanical Behavior of Biomedical Materials
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
2013-05
Subject
The topic of the resource
arborescent; biocompatibility; Biopolymers; block-copolymers; Breast implants; elastomers; Engineering; Histological study; in-vivo; Materials Science; mechanical-properties; polyisobutylene-based biomaterials; polystyrene; prostheses; rupture; SIBS; thermoplastic; women
Creator
An entity primarily responsible for making the resource
Lim G T; Valente S A; Hart-Spicer C R; Evancho-Chapman M M; Puskas J E; Horne W I; Schmidt S P
Description
An account of the resource
One in eight American women develops breast cancer. Of the many patients requiring mastectomy yearly as a consequence, most elect some form of breast reconstruction. Since 2006, only silicone breast implants have been approved by the FDA for the public use. Unfortunately, over one-third of women with these implants experience complications as a result of tissue-material biocompatibility issues, which may include capsular contracture, calcification, hematoma, necrosis and implant rupture. Our group has been working on developing alternatives to silicone. Linear triblock poly(styrene-b-isobutylene-b-styrene) (SIBS) polymers are self-assembling nanostructured thermoplastic rubbers, already in clinical practice as drug eluting stent coatings. New generations with a branched (arborescent or dendritic) polyisobutylene core show promising potential as a biomaterial alternative to silicone rubber. The purpose of this pre-clinical research was to evaluate the material-tissue interactions of a new arborescent block copolymer (TPE1) in a rabbit implantation model compared to a linear SIBS (SIBSTAR 103T) and silicone rubber. This study is the first to compare the molecular weight and molecular weight distribution, tensile properties and histological evaluation of arborescent SIBS-type materials with silicone rubber before implantation and after explantation. (C) 2013 Elsevier Ltd. All rights reserved.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jmbbm.2013.01.025" target="_blank" rel="noreferrer noopener">10.1016/j.jmbbm.2013.01.025</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2013
arborescent
Biocompatibility
Biopolymers
block-copolymers
Breast implants
Department of Pharmaceutical Sciences
elastomers
Engineering
Evancho-Chapman M M
Hart-Spicer C R
Histological study
Horne W I
in-vivo
Journal Article or Conference Abstract Publication
Journal of the Mechanical Behavior of Biomedical Materials
Lim G T
Materials Science
mechanical-properties
NEOMED College of Graduate Studies
NEOMED College of Pharmacy
polyisobutylene-based biomaterials
polystyrene
prostheses
Puskas J E
Rupture
Schmidt S P
SIBS
thermoplastic
Valente S A
Women
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1039/b505706j" target="_blank" rel="noreferrer noopener">http://doi.org/10.1039/b505706j</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1495-1503
Issue
16
Volume
16
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Title
A name given to the resource
Collagen As A Scaffold For Biomimetic Mineralization Of Vertebrate Tissues
Publisher
An entity responsible for making the resource available
Journal of Materials Chemistry
Date
A point or period of time associated with an event in the lifecycle of the resource
2006
2006
Subject
The topic of the resource
3 dimensions; bone; Chemistry; elastic energy-storage; electron-microscopic tomography; fibril structure; i collagen; Materials Science; matrix; mechanical-properties; molecular packing; organic; turkey tendons
Creator
An entity primarily responsible for making the resource
Landis W J; Silver F H; Freeman J W
Description
An account of the resource
Collagen is a well known protein component that has the capacity to mineralize in a variety of vertebrate tissues. In its mineralized form, collagen potentially can be utilized as a biomimetic material for a variety of applications, including, for example, the augmentation and repair of damaged, congenitally defective, diseased or otherwise impaired calcified tissues such as bone and cartilage. In order to effect an optimal response in this regard, the manner in which collagen becomes mineralized is critically important to understand. This paper provides details concerning collagen-mineral interaction and its implications with respect to designing biomimetic mineralizing collagen that will be functionally competent in its biological, chemical, and biomechanical properties.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1039/b505706j" target="_blank" rel="noreferrer noopener">10.1039/b505706j</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2006
3 dimensions
Bone
Chemistry
Department of Family & Community Medicine
elastic energy-storage
electron-microscopic tomography
fibril structure
Freeman J W
i collagen
Journal Article or Conference Abstract Publication
Journal of Materials Chemistry
Landis W J
Materials Science
matrix
mechanical-properties
molecular packing
NEOMED College of Medicine
organic
Silver F H
turkey tendons
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0142-9612(03)00189-3" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0142-9612(03)00189-3</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
3493-3503
Issue
20
Volume
24
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Title
A name given to the resource
Synthesis, Permeability And Biocompatibility Of Tricomponent Membranes Containing Polyethylene Glycol, Polydimethylsiloxane And Polypentamethylcyclopentasiloxane Domains
Publisher
An entity responsible for making the resource available
Biomaterials
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
2003-09
Subject
The topic of the resource
biocompatibility; compatibility; delivery; Engineering; hydrogels; insulin diffusion; Materials Science; membrane; molecular weight cut-off; networks; oxygen diffusion; star; surface-properties; water
Creator
An entity primarily responsible for making the resource
Kurian P; Kasibhatla B; Daum J; Burns C A; Moosa M; Rosenthal K S; Kennedy J P
Description
An account of the resource
The synthesis of "smart" tricomponent amphiphilic membranes containing poly(ethylene glycol) (PEG), polydimethylsiloxane (PDMS) and polypentamethylcyclopentasiloxane (PD(5)) domains is described. Contact angle hysteresis indicates that in air, the surfaces of such PEG/PD(5)/PDMS membranes are enriched by the hydrophobic components, PDMS and PD(5), while in water, the surfaces are rich in the hydrophilic PEG. The oxygen permeability of a series of membranes with varying M(c,hydrophilic) (M(n,PEG) = 4600, 10,000 and 20,000 g/mol) and varying PEG/PD(5)/PDMS compositions was studied. Oxygen permeability increased with the amount of PDMS in the membrane. The molecular weight cut-off (MWCO) ranges and permeability coefficients of insulin through a series of PEG/PD(5)/PDMS(=29/14/57) membranes with varying M(c,hydrophilic) were determined. Insulin permeability is directly related to Mc,hydrophilic of the membrane. MWCO studies show that the membranes are semipermeable to, i.e., allow the transport of smaller proteins such as insulin (M(n) = 5733 g/mol, R(s) = 1.34 nm) and cytochrome c (M(n) = 12,400 g/mol, R(s) = 1.63 nm), but are barriers to larger proteins such as albumin (M(n) = 66,000 g/mol, R(s) = 3.62 nm). Implantation of representative membranes in rats showed them to be biocompatible. According to these studies, PEG/PD(5)/PDMS membranes may be suitable for biological applications, e.g., immunoisolation of cells. (C) 2003 Elsevier Science Ltd. All rights reserved.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0142-9612(03)00189-3" target="_blank" rel="noreferrer noopener">10.1016/s0142-9612(03)00189-3</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2003
Biocompatibility
Biomaterials
Burns C A
compatibility
Daum J
Delivery
Engineering
hydrogels
insulin diffusion
Journal Article or Conference Abstract Publication
Kasibhatla B
Kennedy J P
Kurian P
Materials Science
membrane
molecular weight cut-off
Moosa M
networks
oxygen diffusion
Rosenthal K S
star
surface-properties
Water
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0142-9612(03)00172-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0142-9612(03)00172-8</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
3483-3491
Issue
20
Volume
24
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Title
A name given to the resource
Characterization And Performance Of Membranes Designed For Macroencapsulation/implantation Of Pancreatic Islet Cells
Publisher
An entity responsible for making the resource available
Biomaterials
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
2003-09
Subject
The topic of the resource
amphiphilic networks; amphiphilic polymer membranes; Engineering; glucose challenge; macroencapsulation of pancreatic islets; macroencapsulatory membranes; Materials Science; oxygen permeability; polyisobutylene; rat; stars
Creator
An entity primarily responsible for making the resource
Isayeva I S; Kasibhatla B T; Rosenthal K S; Kennedy J P
Description
An account of the resource
Amphiphilic polymer membranes were synthesized for macroencapsulation of cells and characterized by select chemical and biological techniques. The membranes were prepared by crosslinking hydrophilic poly(N,N-dimethyl acrylamide) (PDMAAm) main chains with hydrophobic di-, tri-, and octa-methacrylate telechelic polyisobutylene (PIB) stars. The hydrophilic/hydrophobic composition and the molecular weights between crosslink sites (both M-c,M-hydrophilic and M-c,M-hydrophobic) were controlled by synthesis conditions. Small tubular membranes were made by in situ rotational copolymerization/crosslinking and filled with pancreatic rat islets. The water-swelling behavior, mechanical properties, and oxygen and insulin diffusion were studied. Macroencapsulatory performance of these membranes was investigated in vitro by macroencapsulation of pancreatic rat islets within tubular membranes for up to 1.5 months, and studying the insulin secreting ability of encapsulated islets in culture. The membranes are robust and maintain their integrity for the period of encapsulation. They allow oxygen and insulin diffusion. Macroencapsulated islets maintained their viability and insulin secretion over an extended period (i.e., 45 days). (C) 2003 Elsevier Science Ltd. All rights reserved.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0142-9612(03)00172-8" target="_blank" rel="noreferrer noopener">10.1016/s0142-9612(03)00172-8</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2003
amphiphilic networks
amphiphilic polymer membranes
Biomaterials
Engineering
glucose challenge
Isayeva I S
Journal Article or Conference Abstract Publication
Kasibhatla B T
Kennedy J P
macroencapsulation of pancreatic islets
macroencapsulatory membranes
Materials Science
oxygen permeability
polyisobutylene
rat
Rosenthal K S
stars
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.biomaterials.2007.12.015" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.biomaterials.2007.12.015</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1676-1685
Issue
11
Volume
29
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Affinity Manipulation Of Surface-conjugated Rgd Peptide To Modulate Binding Of Liposomes To Activated Platelets
Publisher
An entity responsible for making the resource available
Biomaterials
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
2008-04
Subject
The topic of the resource
cyclic RGD; delivery systems; drug-eluting stents; Engineering; insight; integrin alpha(iib)beta(3); liposomes; Materials Science; nanoparticles; peptide modification; platelet-targeting; responses; restenosis; therapy
Creator
An entity primarily responsible for making the resource
Huang G F; Zhou Z M; Srinivasan R; Penn M S; Kottke-Marchant K; Marchant R E; Gupta A S
Description
An account of the resource
Platelet adhesion, activation and fibrinogen-mediated aggregation are primary events in vascular thrombosis and occlusion. An injectable delivery system that can carry thrombolytics selectively to the sites of active platelet aggregation has immense potential in minimally invasive targeted therapy of vascular occlusion. To this end we are studying liposomes surface-modified by fibrinogen-mimetic RGD motifs that can selectively target and bind integrin GPIIb-IIIa on activated platelets. Here we report liposome surface-modification with a conformationally constrained high affinity cyclic RGD motif to modulate the GPIIb-IIIa-binding capability of the liposomes. Such affinity enhancement is important for practical in vivo applications to compete with native fibrinogen towards binding GPIIb-IIIa. The platelet-binding of RGD-modified liposomes was studied by fluorescence and scanning electron microscopy, and flow cytometry, in vitro. Binding of RGD-modified liposomes was also tested in vivo in a rat carotid injury model and analyzed ex vivo by fluorescence microscopy. The results from all experiments show that cyclic RGD-liposomes bind activated platelets significantly higher compared to linear RGD-liposomes. Hence, the results establish the feasibility of modulating the platelet-targeting and binding ability of vascularly targeted liposomes by manipulating the affinity of surface-modifying ligands. (c) 2008 Elsevier Ltd. All rights reserved.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.biomaterials.2007.12.015" target="_blank" rel="noreferrer noopener">10.1016/j.biomaterials.2007.12.015</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2008
Biomaterials
cyclic RGD
delivery systems
Drug-Eluting Stents
Engineering
Gupta A S
Huang G F
insight
integrin alpha(iib)beta(3)
Journal Article or Conference Abstract Publication
Kottke-Marchant K
liposomes
Marchant R E
Materials Science
Nanoparticles
Penn M S
peptide modification
platelet-targeting
responses
Restenosis
Srinivasan R
therapy
Zhou Z M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/jbm.a.34439" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jbm.a.34439</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1502-1510
Issue
5
Volume
101
Search for Full-text
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Dublin Core
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Title
A name given to the resource
2.5d Constructs For Characterizing Phase Separated Polymer Blend Surface Morphology In Tissue Engineering Scaffolds
Publisher
An entity responsible for making the resource available
Journal of Biomedical Materials Research Part A
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
2013-05
Subject
The topic of the resource
2; 3d; 5D scaffolds; cell-shape; differentiation; Engineering; L-lactide); Materials Science; mechanical-properties; poly(D; poly(e-caprolactone); polymer blends; porosity; proliferation; topography
Creator
An entity primarily responsible for making the resource
Marszalek J E; Simon C G; Thodeti C; Adapala R K; Murthy A; Karim A
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/jbm.a.34439" target="_blank" rel="noreferrer noopener">10.1002/jbm.a.34439</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2
2013
3d
5D scaffolds
Adapala R K
cell-shape
differentiation
Engineering
Journal of Biomedical Materials Research Part A
Karim A
L-lactide)
Marszalek J E
Materials Science
mechanical-properties
Murthy A
poly(D
poly(e-caprolactone)
polymer blends
Porosity
proliferation
Simon C G
Thodeti C
topography
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1166/jnn.2017.13449" target="_blank" rel="noreferrer noopener">http://doi.org/10.1166/jnn.2017.13449</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
4867-4881
Issue
7
Volume
17
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Dublin Core
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Title
A name given to the resource
Engineering Alkoxyphenacyl-Polycarbonate Nanoparticles for Potential Application in Near-Infrared Light-Modulated Drug Delivery via Photon Up-Conversion Process
Publisher
An entity responsible for making the resource available
Journal of Nanoscience and Nanotechnology
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-07
Subject
The topic of the resource
800 nm; alkoxylphenacyl-based polycarbonates; biocompatibility; Chemistry; Doxorubicin; Drug Release; luminescence; Materials Science; mesoporous-silica; nanocrystals; Nanotechnology; Near-Infrared Light; photodynamic therapy; Physics; release; Science & Technology - Other Topics; Stimuli-Responsive; upconverting nanoparticles; uv
Creator
An entity primarily responsible for making the resource
Wehrung D; Chamsaz E A; Andrews J H; Joy A; Oyewumi M O
Description
An account of the resource
Photoresponsive delivery systems that are activated by high energy photo-triggers have been accorded much attention because of the capability to achieve reliable photoreactions at short irradiation times. However, the application of a high energy photo-trigger (UV light) is not clinically viable. Meanwhile, the process of photon-upconversion is an effective strategy to generate a high energy photo-trigger (in-situ) through exposure to clinically relevant near-infrared (NIR) light. In this regard, we synthesized photon upconverting nanocrystals (UCNCs) that were subsequently loaded into photoresponsive nanoparticles (NPs) that were prepared using alkoxyphenacyl-based polycarbonate homopolymer (UCNC-APP-NPs). UCNC loading affected resultant NP size, size distribution, colloidal stability but not the zeta potential. The efficiency of NIR-modulated drug delivery was impacted by the heterogenetic nature of the resultant UCNC-APP-NPs which was plausibly formed through a combination of UCNC entrapment within the polymeric NP matrix and nucleation of polymer coating on the surface of the UCNCs. The biocompatibility of UCNC-APP-NPs was demonstrated through cytotoxicity, macrophage activation, and red blood cell lysis assays. Studies in tumor-bearing (nu/nu) athymic mice showed a negligible distribution of UCNC-APP-NPs to reticuloendothelial tissues. Further, distribution of UCNC-APP-NPs to various tissues was in the order (highest to lowest): Lungs> Tumor > Kidneys > Liver > Spleen> Brain > Blood > Heart. In all, the work highlighted some important factors that may influence the effectiveness, reproducibility and biocompatibility of drug delivery systems that operate on the process of photon-upconversion.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1166/jnn.2017.13449" target="_blank" rel="noreferrer noopener">10.1166/jnn.2017.13449</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2017
800 nm
alkoxylphenacyl-based polycarbonates
Andrews J H
Biocompatibility
Chamsaz E A
Chemistry
Department of Pharmaceutical Sciences
Doxorubicin
Drug Release
Journal Article
Journal of nanoscience and nanotechnology
Joy A
luminescence
Materials Science
mesoporous-silica
nanocrystals
Nanotechnology
Near-Infrared Light
NEOMED College of Pharmacy
Oyewumi M O
photodynamic therapy
Physics
release
Science & Technology - Other Topics
Stimuli-responsive
upconverting nanoparticles
uv
Wehrung D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1021/la500905z" target="_blank" rel="noreferrer noopener">http://doi.org/10.1021/la500905z</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
5202-5208
Issue
18
Volume
30
Search for Full-text
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Title
A name given to the resource
Dextran-Peptide Hybrid for Efficient Gene Delivery
Publisher
An entity responsible for making the resource available
Langmuir
Date
A point or period of time associated with an event in the lifecycle of the resource
2014
2014-05
Subject
The topic of the resource
cationic lipids; cells; Chemistry; cytotoxicity; drug delivery; in-vitro; Materials Science; nanoparticles; nonviral vector; plasmid dna; polyethylenimine; therapy
Creator
An entity primarily responsible for making the resource
Tang Q; Cao B; Lei X; Sun B B; Zhang Y Q; Cheng G
Description
An account of the resource
Gene therapy has drawn significant interest in the past two decades since it provides a promising strategy to treat both genetic disorders and acquired diseases. However, the transfer of gene therapy to clinical applications is troubled with many difficulties, since many current systems are of toxicity, low transfection efficiency and low biodegradability. To address these challenges, we developed a dextran-peptide hybrid system as a safe and efficient vector for gene therapy and investigated the structure-function-cytotoxicity relationship of this dextran-peptide hybrid system. Dextrans (Dex10, Dex20, and Dex70) with different molecular weights (10, 20 and 70 kDa) were conjugated with a cationic peptide, R5H5, at various degrees of substitution. Gene expression and cytotoxicity mediated by this delivery system were evaluated against SKOV-3 human ovarian carcinoma cells and compared to 25 kDa branched poly(ethylenimine) (PEI). The results showed that Dex10-R5H5 and Dex20-R5H5 hybrids derived from low molecular weight dextrans induced higher gene expression and lower cytotoxicity than Dex70-R5H5 hybrid from higher molecular weight dextran. The best performance on gene expression was achieved by Dex10-R5H5 at 40% substitution of R5H5, which induced greater gene expression than PEI at a low N/P ratio of S. Dex10-R5H5/DNA complexes at 40% substitution of R5H5 also showed much higher cell viability (93%) than PEI/DNA (66%) at the same N/P ratio. These results indicate that the Dex-R5H5 hybrid with the low molecular weight of dextran and the high degree of substitution of R5H5 is a very promising material for safe and efficient gene therapy.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1021/la500905z" target="_blank" rel="noreferrer noopener">10.1021/la500905z</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2014
Cao B
Cationic lipids
Cells
Chemistry
Cheng G
cytotoxicity
Drug delivery
in-vitro
Journal Article
Langmuir
Lei X
Materials Science
Nanoparticles
nonviral vector
plasmid dna
polyethylenimine
Sun B B
Tang Q
therapy
Zhang Y Q
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s10856-015-5460-0" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s10856-015-5460-0</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
9-9
Issue
3
Volume
26
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Infusion of iodine-based contrast agents into poly(p-dioxanone) as a radiopaque resorbable IVC filter
Publisher
An entity responsible for making the resource available
Journal of Materials Science-Materials in Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
2015-03
Subject
The topic of the resource
degradation; Engineering; in-vivo; Materials Science; release; triclosan; vena-cava filters
Creator
An entity primarily responsible for making the resource
Singhana B; Chen A; Slattery P; Yazdi I K; Qiao Y; Tasciotti E; Wallace M; Huang S; Eggers M; Melancon M P
Description
An account of the resource
To determine the feasibility of infusing resorbable inferior vena cava (IVC) filter with iodine-based contrast agents to produce a radiopaque, computed tomography (CT)-visible IVC filter. Infused poly(p-dioxanone) (PPDO) was obtained by incubating PPDO in different concentrations of 4-iodobenzoyl chloride (IBC) and 2,3,5-triiodobenzoic acid (TIBA). Characterizations of infused and nascent PPDO were done using elemental analysis, micro-CT, tensile strength analysis, scanning electron microscopy, and differential scanning calorimetry. Elemental analysis showed percentage loading of 1.07 +/- 0.08 for IBC and 0.73 +/- 0.01 for TIBA. The iodine loading remained the same within 2 weeks for TIBA but decreased to about 80 % with IBC when subjected to physiological conditions. Micro-CT images showed increased attenuation of the infused PPDO compared with the nascent PPDO. The Hounsfield unit values for infused and nascent sutures were 110 +/- 40 and 153 +/- 53 for PPDO infused with 2 mg/mL IBC and TIBA, respectively, but only 11.35 +/- 2 for nascent PPDO. In contrast the HU for bone was 116 +/- 37. Tensile strength analysis showed maximum loads of 1.01 +/- 0.43 kg and 10.02 +/- 0.54 kg for IBC and TIBA, respectively, and 10.10 +/- 0.64 kg for nascent PPDO. Scanning electron microscopy showed that the morphology of the PPDO surface did not change after coating and preliminary cytotoxicity assay showed no killing effect on Hela cells. PPDO infused with a contrast agent is significantly more radiopaque than nascent PPDO on micro-CT imaging. This radiopacity could allow the position and integrity of infused resorbable IVC filter to be monitored while it is in place, thus increasing its safety and efficacy as a medical device.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s10856-015-5460-0" target="_blank" rel="noreferrer noopener">10.1007/s10856-015-5460-0</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2015
Chen A
degradation
Eggers M
Engineering
Huang S
in-vivo
Journal Article
Journal of Materials Science-Materials in Medicine
Materials Science
Melancon M P
Qiao Y
release
Singhana B
Slattery P
Tasciotti E
triclosan
vena-cava filters
Wallace M
Yazdi I K
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1080/15421400590957288" target="_blank" rel="noreferrer noopener">http://doi.org/10.1080/15421400590957288</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
587-598
Volume
434
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Lyotropic chromonic liquid crystals for biological sensing applications
Publisher
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Molecular Crystals and Liquid Crystals
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
2005
Subject
The topic of the resource
biosensor; cells; Chemistry; chromonics; Crystallography; ligand-receptor binding; liquid crystal; Materials Science
Creator
An entity primarily responsible for making the resource
Shiyanovskii S V; Lavrentovich O D; Schneider T; Ishikawa T; Smalyukh I I; Woolverton C J; Niehaus G D; Doane K J
Description
An account of the resource
We describe director distortions in the nematic liquid crystal (LC) caused by a spherical particle with tangential surface orientation of the director and show that light transmittance through the distorted region is a steep function of the particle's size. The effect allows us to propose a real-time microbial sensor based on a lyotropic chromonic LC (LCLC) that detects and amplifies the presence of immune complexes. A cassette is filled with LCLC, antibody, and antigen-bearing particles. Small and isolated particles cause no macroscopic distortions of the uniformly aligned LCLC. Upon antibody-antigen binding, the growing immune complexes.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1080/15421400590957288" target="_blank" rel="noreferrer noopener">10.1080/15421400590957288</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2005
biosensor
Cells
Chemistry
chromonics
Crystallography
Doane K J
Ishikawa T
Journal Article
Lavrentovich O D
ligand-receptor binding
liquid crystal
Materials Science
Molecular Crystals and Liquid Crystals
Niehaus G D
Schneider T
Shiyanovskii S V
Smalyukh I I
Woolverton C J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/(sici)1097-4636(199705)35:2%3C157::aid-jbm3%3E3.0.co;2-m" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/(sici)1097-4636(199705)35:2%3C157::aid-jbm3%3E3.0.co;2-m</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
157-163
Issue
2
Volume
35
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Amphiphilic networks .10. Diffusion of glucose and insulin (and nondiffusion of albumin) through amphiphilic membranes
Publisher
An entity responsible for making the resource available
Journal of Biomedical Materials Research
Date
A point or period of time associated with an event in the lifecycle of the resource
1997
1997-05
Subject
The topic of the resource
cells; Drug Release; Engineering; Materials Science; pancreas; sequential co-polymers; telechelic polymers; transfer agents inifers
Creator
An entity primarily responsible for making the resource
Shamlou S; Kennedy J P; Levy R P
Description
An account of the resource
Select semipermeable amphiphilic membranes have been prepared and their diffusional characteristics for glucose, insulin, and albumin investigated. The membranes were prepared by cast copolymerization of a hydrophilic monomer (i.e., N,N-dimethyl acrylamide, or N,N-dimethylaminoethyl methacrylate) with the hydrophobic crosslinker methacrylate-ditelechelic polyisobutylene. The products have sufficient mechanical properties for the fabrication of swollen membranes, sheets, tubes, etc. Membranes have been identified which allowed the rapid simultaneous countercurrent diffusion of glucose (M-n = 180 Da) and insulin (M-n = 5733 Da) but did not allow albumin (Mn similar to 60,000 Da) to pass. Evidently, the effective molecular weight cutoff point of these membranes is in the 6-60-KDa range. (C) 1997 John Wiley & Sons, Inc.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/(sici)1097-4636(199705)35:2%3C157::aid-jbm3%3E3.0.co;2-m" target="_blank" rel="noreferrer noopener">10.1002/(sici)1097-4636(199705)35:2%3C157::aid-jbm3%3E3.0.co;2-m</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
1997
Cells
Drug Release
Engineering
Journal Article
Journal of Biomedical Materials Research
Kennedy J P
Levy R P
Materials Science
Pancreas
sequential co-polymers
Shamlou S
telechelic polymers
transfer agents inifers
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/adem.201500282" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/adem.201500282</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
518-531
Issue
4
Volume
18
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A Novel Hybrid-Structured Titanium Surface Promotes Adhesion of Human Dermal Fibroblasts and Osteogenesis of Human Mesenchymal Stem Cells while Reducing S-epidermidis Biofilm Accumulation
Publisher
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Advanced Engineering Materials
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-04
Subject
The topic of the resource
differentiation; energy; hydrophilicity; implants; in-vitro; Materials Science; nanotopography; osseointegration; osteoactivin; osteoblast lineage cells; responses
Creator
An entity primarily responsible for making the resource
Park B W; Krieger J; Sondag G R; Moussa F M; Rankenberg J; Safadi F F; Gatsonis N A; McGimpsey W G; Lambert C R; Malcuit C
Description
An account of the resource
We provide a comparative analysis of protein adsorption, primary human cell behavior, and biofilm formation on modified titanium substrates of either micro-, nano-, or hybrid micro/nano-scale feature sizes. While studies revealed that nano-scale structures initially decreased the attachment and spreading of both human fibroblasts (hDFs) and mesenchymal stem cells (hMSCs), hMSC differentiation studies revealed that hybrid structures promoted the highest levels of osteogenic gene expression and attenuated biofilm formation by Staphylococcus epidermidis. Taken together, this novel approach of generating a hybrid topographical feature results in a potential implant material capable of enhanced dermal cell adhesion and osteogenic differentiation while limiting biofilm accumulation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/adem.201500282" target="_blank" rel="noreferrer noopener">10.1002/adem.201500282</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2016
Advanced Engineering Materials
differentiation
energy
Gatsonis N A
hydrophilicity
Implants
in-vitro
Journal Article
Krieger J
Lambert C R
Malcuit C
Materials Science
McGimpsey W G
Moussa F M
nanotopography
osseointegration
OSTEOACTIVIN
osteoblast lineage cells
Park B W
Rankenberg J
responses
Safadi F F
Sondag G R