Browse Items (6 total)
- Tags: McBurney Denise
Tags: *Biological Evolution, 2017, Animals, baleen, baleen whales, bowhead whale, Bowhead Whale/anatomy & histology/*embryology, Cetacea, Dentition, Department of Anatomy & Neurobiology, embryology, Female, FGF, George John C, Hieronymus Tobin L, Jaw/anatomy & histology/embryology, Journal of anatomy, keratin, McBurney Denise, Mixed, Mouth/anatomy & histology/*embryology, mysticetes, NEOMED College of Medicine, ontogeny, Pregnancy, Stimmelmayr Raphaela, Suydam Robert, Thewissen J G M, tooth development, Tooth/anatomy & histology/*embryology
Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.
Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko
Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis.
Tags: 2005, Animals, Annexin A5/metabolism, Anti-Bacterial Agents/metabolism, Apoptosis/*physiology, Biomarkers, Carlson Sara G, Caspase 12, Caspases/metabolism, CCAAT-Enhancer-Binding Proteins/metabolism, Cell Differentiation/*physiology, Cells, Chondrocytes/cytology/*physiology, Collagen Type II/metabolism, Cultured, Department of Anatomy & Neurobiology, DNA Fragmentation, Endoplasmic Reticulum/*metabolism, Extracellular Matrix/metabolism, Gene Expression Regulation, Glucose/metabolism, Horton Walter E Jr, McBurney Denise, NEOMED College of Medicine, Proliferating Cell Nuclear Antigen/metabolism, Rats, Signal Transduction/*physiology, Thapsigargin/metabolism, The Journal of biological chemistry, Transcription Factor CHOP, Transcription Factors/metabolism, Tunicamycin/metabolism, Yang Ling
Intrajoint comparisons of gene expression patterns in human osteoarthritis suggest a change in chondrocyte phenotype.
Tags: *Gene Expression Profiling, 2005, 80 and over, Aged, Articular/*metabolism, Cartilage, Chondrocytes/*metabolism, Collagen Type II/genetics, Department of Anatomy & Neurobiology, Glycosaminoglycans/analysis, High Mobility Group Proteins/genetics, Horton Walter E Jr, Humans, Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Laverty David, Matrix Metalloproteinase 3/genetics, Matrix Metalloproteinase 9/genetics, McBurney Denise, Messenger/analysis, NEOMED College of Medicine, Osteoarthritis/*metabolism, Phenotype, Proto-Oncogene Proteins c-bcl-2/genetics, RNA, SOX9 Transcription Factor, Transcription Factors/genetics, Weiner Scott, Yagi Rieko
A novel role for Bcl-2 associated-athanogene-1 (Bag-1) in regulation of the endoplasmic reticulum stress response in mammalian chondrocytes.
Tags: *Gene Expression Regulation, 2007, Animals, Apoptosis, Biological, Carlson Sara G, Cell Proliferation, Chondrocytes/*metabolism/pathology, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, DNA-Binding Proteins/*metabolism/physiology, Endoplasmic Reticulum/metabolism, Horton Walter E Jr, Journal of cellular biochemistry, McBurney Denise, Models, NEOMED College of Medicine, Phenotype, Rats, RNA Interference, Subcellular Fractions/metabolism, Tang Shou-Ching, Time Factors, Transcription Factors/*metabolism/physiology, Transfection, Yang Ling
Tags: 2004, Aging/*metabolism, Animals, Articular/cytology/*metabolism, Carrier Proteins/genetics/*metabolism, Cartilage, Cell Division/physiology, Cells, Chondrocytes/cytology/*metabolism, Cultured, Department of Anatomy & Neurobiology, DNA-Binding Proteins, Gene Expression Regulation, Growth Plate/*metabolism, Horton Walter E Jr, Inbred C57BL, Kinkel Mary D, McBurney Denise, Mice, NEOMED College of Medicine, Nugent Ashleigh, Proto-Oncogene Proteins c-bcl-2/*metabolism, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology, Tissue Distribution, Transcription Factors, Yagi Rieko