1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0165-0270(00)00161-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0165-0270(00)00161-8</a>
Pages
31–35
Issue
1
Volume
97
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Secure cranial-mount intrathecal cannulation - a spinal administration technique in the rat.
Publisher
An entity responsible for making the resource available
Journal of neuroscience methods
Date
A point or period of time associated with an event in the lifecycle of the resource
2000
2000-04
Subject
The topic of the resource
Analgesics; Anesthesia; Animals; Dose-Response Relationship; Drug; Injections; Microinjections; Morphine/administration & dosage/pharmacology; Opioid/administration & dosage/pharmacology; Rats; Spinal Cord/*physiology; Spinal/*instrumentation; Sprague-Dawley; Stereotaxic Techniques/*instrumentation
Creator
An entity primarily responsible for making the resource
Schechter J B; Crisp T
Description
An account of the resource
In order to identify an acute spinally mediated pharmacological effect of a bioactive substance, without incurring untoward supraspinal effects, it is necessary to administer the agent locally onto the spinal cord. The procedure delineated herein presents a modern technique to install a stable, permanent indwelling thecal cannulae with a cranially mounted aperture, and details a simple, repeatable administration system. These methods facilitate a quick, noninvasive spinal drug microadministration that is most useful for differentiation of the locus of pharmacological action without the behavioral disruption associated with other administration methodologies.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0165-0270(00)00161-8" target="_blank" rel="noreferrer noopener">10.1016/s0165-0270(00)00161-8</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2000
Analgesics
Anesthesia
Animals
Crisp T
Dose-Response Relationship
Drug
Injections
Journal of neuroscience methods
Microinjections
Morphine/administration & dosage/pharmacology
Opioid/administration & dosage/pharmacology
Rats
Schechter J B
Spinal Cord/*physiology
Spinal/*instrumentation
Sprague-Dawley
Stereotaxic Techniques/*instrumentation
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0361-9230(93)90075-m" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0361-9230(93)90075-m</a>
Pages
195–200
Issue
2
Volume
32
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Topographic organization of efferent projections of medial frontal cortex.
Publisher
An entity responsible for making the resource available
Brain research bulletin
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1905-06
Subject
The topic of the resource
Animals; Brain Mapping/*methods; Efferent Pathways/physiology; Female; Fluorescent Dyes; Frontal Lobe/*physiology; Male; Microinjections; Rats; Sprague-Dawley; Superior Colliculi/physiology; Tegmentum Mesencephali/physiology
Creator
An entity primarily responsible for making the resource
Zeng D; Stuesse S L
Description
An account of the resource
By using fluorescent retrograde tracers, we compared efferent projections of the medial frontal cortex to two subcortical areas: the superior colliculus, a somatic motor area, and the laterodorsal tegmental nucleus, a visceral motor area. Neurons projecting to the superior colliculus originated in layer V of the cingulate (Cg1 area) and medial agranular cortex, while neurons projecting to the laterodorsal tegmental nucleus originated in layers V and VI of the cingulate (Cg3 area) and infralimbic cortex. Thus, within the medial frontal cortex, the ventral portion (the Cg3 and infralimbic areas) may be a visceral motor area while the dorsal portion is a somatic motor region.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0361-9230(93)90075-m" target="_blank" rel="noreferrer noopener">10.1016/0361-9230(93)90075-m</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1993
Animals
Brain Mapping/*methods
Brain research bulletin
Efferent Pathways/physiology
Female
Fluorescent Dyes
Frontal Lobe/*physiology
Male
Microinjections
Rats
Sprague-Dawley
Stuesse S L
Superior Colliculi/physiology
Tegmentum Mesencephali/physiology
Zeng D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0091-3057(92)90007-3" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0091-3057(92)90007-3</a>
Pages
619–623
Issue
4
Volume
42
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Direct microinjection of cathinone into the rat brain produces discriminative stimuli.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-08
Subject
The topic of the resource
*Brain/anatomy & histology; Alkaloids/administration & dosage/*pharmacology; Animals; Discrimination (Psychology)/*drug effects; Discrimination Learning/drug effects; Dose-Response Relationship; Drug; Inbred Strains; Injections; Intraventricular; Male; Microinjections; Nucleus Accumbens/anatomy & histology; Psychotropic Drugs/*pharmacology; Rats
Creator
An entity primarily responsible for making the resource
Schechter M D; Schechter J B; Calcagnetti D J
Description
An account of the resource
Rats were trained to discriminate IP administration of 800 micrograms/kg cathinone using a food-motivated, two-lever discrimination procedure. Following training, 800 micrograms/kg cathinone discrimination was produced (generalized) by lower cathinone doses in a dose-responsive manner after IP administration; an ED50 value of 330 micrograms/kg was calculated. Subsequently, guide cannulae were implanted into the lateral ventricle and bilaterally into the nucleus accumbens. After recovery, injections were made via cannulae that extended 0.5 mm past the tip of the guide cannulae. ICV administration of 256 micrograms cathinone/rat produced discriminative responding on the cathinone-appropriate lever to the same degree as did the peripherally administered training dose of cathinone. Decreasing ICV doses produced decreased discriminative performance and allowed the calculation of an ED50 value of 90.5 micrograms. Likewise, administration of 64 micrograms cathinone/nucleus accumbens (for a total of 128 micrograms/rat) substituted for the IP training dose of cathinone. These results evidence the central mediation of the cathinone-induced discriminative stimulus cue and show that administration of cathinone into the nucleus accumbens is sufficient to produce these stimuli. Thus, these data suggest that receptors in the nucleus accumbens are important for the discrimination of this psychostimulant.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0091-3057(92)90007-3" target="_blank" rel="noreferrer noopener">10.1016/0091-3057(92)90007-3</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Brain/anatomy & histology
1992
Alkaloids/administration & dosage/*pharmacology
Animals
Calcagnetti D J
Discrimination (Psychology)/*drug effects
Discrimination Learning/drug effects
Dose-Response Relationship
Drug
Inbred Strains
Injections
Intraventricular
Male
Microinjections
Nucleus Accumbens/anatomy & histology
Pharmacology, biochemistry, and behavior
Psychotropic Drugs/*pharmacology
Rats
Schechter J B
Schechter M D