Browse Items · NEOMED Bibliography Database

Ultrastructural aspects of human gallbladder epithelial cells in cholelithiasis: production of anionic mucus.

The surface epithelium of 28 gallbladders removed during elective cholecystectomies and pathology collection was studied ultrastructurally. Focusing on 10 of the 28 cases that were diagnosed as cholecystitis, we found that the epithelium displayed…

Human gallbladder mucosa ultrastructure: evidence of intraepithelial nerve structures.

The zinc iodide-osmium tetroxide (ZIO) fixative-staining method was used along with topographical ultrastructure to investigate cholecystectomized human gallbladders under light and electron microscopic techniques. This method delineated neuronal…

Tags: 1989, Electron/methods, Epithelial Cells, Epithelium/ultrastructure, Gallbladder/cytology/innervation/*ultrastructure, Gilloteaux J, Humans, Kelly T R, Mast Cells/ultrastructure, Microscopy, Mucous Membrane/cytology/ultrastructure, Nerve Endings/ultrastructure, Osmium Tetroxide, Pomerants B, Staining and Labeling/methods, The American journal of anatomy, Zinc

Endocardial surface and atrial morphological changes during development and aging.

Light, scanning, and transmission electron microscopic observations related to morphological changes of the right atrium as well as the atrial endocardium during development (15th embryonic day and 1 day old) and aging (560 days old) in the Syrian…

Tags: *Aging, 1989, Animals, Cricetinae, Electron, Embryonic and Fetal Development, Endocardium/embryology/growth & development/*ultrastructure, Endothelium/ultrastructure, Female, Gilloteaux J, Heart Atria/embryology/growth & development/*ultrastructure, Linz D, Male, Mesocricetus, Microscopy, Microvilli/ultrastructure, Pregnancy, Scanning, The American journal of anatomy

Apical excrescences in the gallbladder epithelium of the female Syrian hamster in response to medroxyprogesterone.

All the intact female Syrian hamsters treated with medroxyprogesterone (MP) for a one-month period, without dietary manipulation, display gallbladder surface epithelial changes, and intraluminal deposits. These changes include excrescences in various…

Murine metapodophalangeal sesamoid bones: morphology and potential means of mineralization underlying function.

Normal murine metapodophalangeal sesamoid bones, closely associated with tendons, were examined in terms of their structure and mineralization with reference to their potential function following crystal deposition. This study utilized radiography,…

Persistence of intact retinal ganglion cell terminals after axonal transport loss in the DBA/2J mouse model of glaucoma.

Axonal transport defects are an early pathology occurring within the retinofugal projection of the DBA/2J mouse model of glaucoma. Retinal ganglion cell (RGC) axons and terminals are detectable after transport is affected, yet little is known about…

Tags: *Axonal Transport/physiology, *bouton, *Mitochondria, *neurodegeneration, *retinal, *RRID:IMSRJAX:000671, *RRID:IMSRJAX:007048, *RRID:SCR002716, *RRID:SCR002865, *superior colliculus, *synapse, 2016, Animal, Animals, Crish Samuel D, Dengler-Crish Christine M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Disease Models, Electron, Fening Kelly M, Glaucoma/metabolism/*pathology, Imaging, Inbred DBA, Inman Denise M, Mice, Microscopy, Mitochondria/pathology, NEOMED College of Medicine, NEOMED College of Pharmacy, Neuroanatomical Tract-Tracing Techniques, Regression Analysis, Retinal Ganglion Cells/metabolism/*pathology, Scanning, Schofield Brett R, Smith Matthew A, Superior Colliculi/metabolism/*pathology, Synapses/metabolism/*pathology, The Journal of comparative neurology, Three-Dimensional, Visual Pathways/metabolism/pathology, Xia Christina Z

Subcellular localization and antiviral activity of carminic acid/poly r(A-U) combinations.

Carminic acid (CAR) enhances the antiviral activity of poly r(A-U) twelve-fold without increasing interferon induction, inactivating the vesicular stomatitis virus or inducing host cell cytotoxicity. Phase contrast photomicrographs of human foreskin…

Pertubation of beta1 integrin function using anti-sense or function-blocking antibodies on corneal cells grown on fibronectin and tenascin.

During corneal development, neural crest derivatives from the periocular mesenchyme migrate into the cornea and differentiate into corneal fibroblasts. During this time, these cells interact with a variety of extracellular matrices for proper…

Aspects of mineral structure in normally calcifying avian tendon.

Structural characteristics of normally calcifying leg tendons of the domestic turkey Meleagris gallopavo have been observed for the first time by tapping mode atomic force microscopy (TMAFM), and phase as well as corresponding topographic images were…

Tags: 2001, Anatomic, Animals, Atomic Force/methods, Calcification, Collagen/chemistry/ultrastructure, Journal of structural biology, Landis W J, Microscopy, Minerals/*chemistry, Models, Molecular, Non-programmatic, Physiologic, Siperko L M, Tendons/*chemistry/*ultrastructure, Turkeys

Anterograde Tract Tracing for Assaying Axonopathy and Transport Deficits in Glaucoma.

Whether to stage degeneration or investigate early pathology in glaucoma, examination of axonal structure and function is essential. There are a wide variety of methods available to investigators using animal models of glaucoma, with varying…

A block in glycoprotein processing correlates with small plaque morphology and virion targetting to cell-cell junctions for an oral and an anal strain of herpes simplex virus type-1.

The characteristics of two clinical isolates of HSV-1 obtained from an oral (424) and an anal (490) lesion were compared with the highly passaged KOS strain. In contrast to KOS, the clinical isolates produced small plaques, were more cell-associated…

Female sex steroid induced epithelial changes in the gallbladder of the ovariectomized Syrian hamster.

Ovariectomized Syrian hamsters treated by female sex steroids during a 1-month period show gallbladder surface epithelial changes in the fundic area consistent with apical bulging and decapitations of the epithelial cells. These events were detected…

N-methyl-D-aspartate receptor-independent long-term potentiation in area CA1 of rat hippocampus: input-specific induction and preclusion in a non-tetanized pathway.

We previously reported that an N-methyl-D-aspartate receptor-independent component of long-term potentiation with an apparent delayed onset can be induced in area CA1 of the hippocampus. Here we show that some but not all of this delay in onset can…

Tags: 1992, 2-Amino-5-phosphonovalerate/*pharmacology, Animals, Electron, Evoked Potentials/drug effects, Grover L M, Hippocampus/*physiology, In Vitro Techniques, Microscopy, N-Methyl-D-Aspartate/*physiology, N-Methylaspartate/*pharmacology, Neuroscience, Pyramidal Tracts/drug effects/*physiology, Rats, Receptors, Teyler T J, Time Factors

Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells.

Resveratrol inhibits herpes simplex virus (HSV) replication by an unknown mechanism. Previously it was suggested that this inhibition may be mediated through a cellular factor essential for HSV replication [Docherty, J.J., Fu, M.M., Stiffler, B.S.,…

Pathways from auditory cortex to the cochlear nucleus in guinea pigs.

The inferior colliculus (IC) and superior olivary complex (SOC) are important sources of descending pathways to the cochlear nucleus. The IC and SOC are also targets of direct projections from the auditory cortex but it is not known if cortical axons…

Projections from auditory cortex contact ascending pathways that originate in the superior olive and inferior colliculus.

The superior olivary complex (SOC) and inferior colliculus (IC) are targets of cortical projections as well as sources of major ascending auditory pathways. This study examines whether the cortical projections contact cells in the SOC or IC that…

Tags: 2007, Animals, Auditory Cortex/*cytology, Auditory Pathways/*cytology, Department of Anatomy & Neurobiology, Fluorescence, Guinea Pigs, Hearing research, Inferior Colliculi/*cytology, Microscopy, NEOMED College of Medicine, Olivary Nucleus/*cytology, Peterson Diana Coomes, Schofield Brett R, Staining and Labeling/methods

Auditory cortical axons contact commissural cells throughout the guinea pig inferior colliculus.

Projections from auditory cortex (AC) affect how cells in both inferior colliculi (IC) respond to acoustic stimuli. The large projection from the AC to the ipsilateral IC is usually credited with the effects in the ipsilateral IC. The circuitry…

Tags: 2013, AC, Animals, auditory cortex, Auditory Cortex/*physiology, Auditory Pathways/cytology, Axons/metabolism/*pathology, Brain Mapping, cortical layers, Department of Anatomy & Neurobiology, Fast Blue, FB, FD, Female, FG, Fluor0Ruby, fluorescein dextran, Fluorescence, FluoroGold, FR, G-, G+, GAD, GAD-immunonegative, GAD-immunopositive, GAD-neg, gamma-Aminobutyric Acid/metabolism, GB, Glutamate Decarboxylase/metabolism, glutamic acid decarboxylase, green RetroBeads, Guinea Pigs, Hearing research, I-VI, IC, IC central nucleus, IC dorsal cortex, IC lateral cortex, IC rostral cortex, ICc, ICd, IClc, ICrc, Inferior Colliculi/pathology/*physiology, inferior colliculus, Male, Mesencephalon/pathology, Microscopy, Nakamoto Kyle T, NEOMED College of Medicine, ps, pseudosylvian sulcus, rhinal sulcus, rs, Schofield Brett R, Sowick Colleen S, white matter, wm

Variation in quantitative measures of enamel prisms from different species as assessed using confocal microscopy.

This study presents a statistical analysis of variability in six measures of enamel prism and ameloblast size and spacing gathered using confocal microscopy, and applies the results to a consideration of appropriate sampling strategies for taxonomic…

Tags: 1996, Animals, Archives of oral biology, Chiroptera/anatomy & histology, Confocal, Crystallography, Dental Enamel/*ultrastructure, Dumont E R, Electron, Galago/anatomy & histology, Insectivora/anatomy & histology, Lemur/anatomy & histology, Lemuridae/anatomy & histology, Mammals/*anatomy & histology, Microscopy, Primates/anatomy & histology, Scanning, Species Specificity

Flow cytometric and ultrastructural aspects of the synergistic antitumor activity of vitamin C-vitamin K3 combinations against human prostatic carcinoma cells.

Transmission and scanning electron microscopy and flow cytometry were employed to characterize the cytotoxic effects of vitamin C (VC), vitamin K3 (VK3), or VC-VK3 combinations on a human prostate carcinoma cell line (DU145) following a 1-h vitamin…

Ultrastructural nucleolar alterations induced by an ametantrone–poly r(A-U) complex.

The current study has documented changes in the ultrastructure as well as in the intranucleolar distribution of rDNA and rRNA in RT4 (human transitional cell bladder carcinoma) cell nucleoli following a 3-h exposure to toxic doses of 50 microM…

Auditory nerve fiber differences in the normal and neurofilament deficient Japanese quail.

A primary axonal disease affecting the central and peripheral nervous system was discovered in a mutant strain of the Japanese quail, named quiver (Quv). We have previously demonstrated altered auditory evoked potentials in the neurofilament (NF)…

Tags: *Mutation, 2001, Animals, Auditory, Axons/ultrastructure, Brain Stem, Cochlear Nerve/*pathology/*physiopathology, Coturnix/genetics, Electron, Evoked Potentials, Hearing research, Kaga K, Microscopy, Mizutani M, Myelin Sheath/ultrastructure, Nerve Fibers/pathology/physiology, Neurofilament Proteins/*deficiency/*genetics, Sheykholeslami K

Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro.

Atherosclerosis, a major macrovascular complication associated with diabetes, poses a tremendous burden on national health care expenditure. Despite extensive efforts, cost-effective remedies are unknown. Therapies for atherosclerosis are challenged…

Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.

Bcl-2 is an anti-apoptotic protein that has recently been shown to regulate other cellular functions. We previously reported that Bcl-2 regulates chondrocyte matrix gene expression, independent of its anti-apoptotic function. Here, we further…

Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko

Development of bone and cartilage in tissue-engineered human middle phalanx models.

Human middle phalanges were tissue-engineered with midshaft scaffolds of poly(L-lactide-epsilon-caprolactone) [P(LA-CL)], hydroxyapatite-P(LA-CL), or beta-tricalcium phosphate-P(LA-CL) and end plate scaffolds of bovine chondrocyte-seeded polyglycolic…

Tags: *Models, 2009, Aggrecans/genetics/metabolism, Animals, Biological, Bone Development/drug effects/*physiology, Calcium Phosphates/pharmacology, Cartilage/cytology/drug effects/*growth & development, Cattle, Chondrocytes/cytology/drug effects/metabolism, Collagen Type II/genetics/metabolism, Durapatite/pharmacology, Electron, Enjo Mitsuhiro, Experimental, Finger Phalanges/cytology/diagnostic imaging/drug effects/*physiology, Gene Expression Profiling, Gene Expression Regulation/drug effects, Humans, Implants, Integrin-Binding Sialoprotein, Isogai Noritaka, Jacquet Robin, Landis William J, Lowder Elizabeth, Mice, Microscopy, Paraffin Embedding, Periosteum/cytology/drug effects, Polyesters/pharmacology, Radiography, Scanning, Sialoglycoproteins/genetics/metabolism, Tissue engineering. Part A, Tissue Engineering/*methods, Tissue Scaffolds/chemistry, Wada Yoshitaka

Sole Dependence on Urine Testing Strips and the Ability to Identify Clinically Significant Disease: Challenging the Current Paradigm for Heme Detection in General Clinical Situations.

BACKGROUND: The ability of health care professionals to provide patient care is potentially compromised when predicated on untested, although longstanding, perspectives. One such example is urinalysis testing, which has been currently simplified to…

Mild acidic pH inhibition of the major pathway of herpes simplex virus entry into HEp-2 cells.

Penetration of the KOS strain of herpes simplex virus type 1 (HSV-1) and the MS and 333 strains of herpes simplex virus type 2 (HSV-2) into HEp-2 cells at pH 6.3 was at least 100-fold less efficient than at pH 7.4. Penetration of two low passage…

Iron localization in superficial siderosis of the central nervous system.

Originally conceived as an uncommon disorder, with the advent of MRI, CNS superficial siderosis has been observed more frequently. We present histologic, histochemical, immunohistochemical, immunofluorescent and ultrastructural evaluation of a…

Temporal changes in left ventricular function after massive sympathetic nervous system activation.

Intense activation of the sympathetic nervous system (SNS) decreases the contractile state of the rabbit left ventricle (LV). In this study, we determined the time course of LV dysfunction after massive central activation of the SNS in dogs.…

Redox-dependent coronary metabolic dilation.

We have observed that hydrogen peroxide (H2O2), the dismutated product of superoxide, is a coronary metabolic dilator and couples myocardial oxygen consumption to coronary blood flow. Because the chemical activity of H2O2 favors its role as an…

Tags: *Paracrine Communication, *Vasodilation/drug effects, 2007, Acetylcysteine/pharmacology, American journal of physiology. Heart and circulatory physiology, Animals, Antioxidants/pharmacology, Cardiac/drug effects/*metabolism, Chilian William M, Conditioned/metabolism, Coronary Vessels/drug effects/enzymology/*metabolism, Culture Media, Department of Integrative Medical Sciences, Dick Gregory M, Dithiothreitol/pharmacology, Enzyme Activation, Fluorescence, Hydrogen Peroxide/metabolism, Imidazoles/pharmacology, In Vitro Techniques, Kiyooka Takahiko, Microscopy, Myocytes, NEOMED College of Medicine, Nitroprusside/pharmacology, Oxidation-Reduction, p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism, Park Yoonjung, Phosphorylation, Protein Kinase Inhibitors/pharmacology, Pyridines/pharmacology, Rats, Reactive Oxygen Species/*metabolism, Reducing Agents/pharmacology, Rocic Petra, Rogers Paul A, Saitoh Shu-ichi, Sulfhydryl Compounds/*metabolism, Swafford Albert, Vasodilator Agents/pharmacology, Viswanathan Chandrasekar, Wistar, Zhang Cuihua

Effect of high transcapillary pressures on capillary ultrastructure and permeability coefficients in dog lung.

To determine the correlation between ultrastructural and physiological changes in blood-gas barrier function in lungs transiently exposed to very high vascular pressures, we increased capillary transmural pressure (Ptm) of 6 canine isolated perfused…

Mitochondrial morphology differences and mitophagy deficit in murine glaucomatous optic nerve.

PURPOSE: Decreased ATP correlates with intraocular pressure exposure in the optic nerves of mice with glaucoma. To understand what underlies this energy deficit, we examined mitochondria in the myelinated optic nerve axons of the DBA/2J mouse, a…

Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins.

BACKGROUND: Metabotropic glutamate receptors (mGluRs) regulate neuronal excitability and synaptic strength. The group I mGluRs, mGluR1 and 5, are widespread in the brain and localize to post-synaptic sites. The Homer protein family regulates group I…

Focal ellipsoid deposits in the atrial myocytes of Syrian hamster.

A peculiar hyaline sarcoplasmic inclusion in the atrial myocytes of old female Syrian hamsters is described. This type of inclusion resembles that described in rare human cardiomyopathy. They have also been described in other rodents and have been…

Tags: 1994, Animals, Cricetinae, Female, Gilloteaux J, Heart Atria/metabolism/*ultrastructure, Immunoelectron, Immunohistochemistry, Inclusion Bodies/metabolism/*ultrastructure, Jennes L, Male, Mesocricetus, Microscopy, Stoeckel M E, Ultrastructural pathology, Vanderhaeghen J J

The pathology of lysosomal storage diseases.

Tags: 1995, Agamanolis D P, Electron, Humans, Lysosomal Storage Diseases/*complications/enzymology/genetics/*pathology, Lysosomes/enzymology, Microscopy, Pathology annual

Office dermatologic testing: the Tzanck preparation.

Whether a vesicobullous disease is intraepidermal or subepidermal is often difficult to determine from the clinical examination. The Tzanck preparation can provide clues that aid in the diagnosis of a number of diseases. It is particularly helpful in…

Tags: *Azure Stains, *Office Visits, 1991, American family physician, Brodell R T, Clinical Protocols/standards, Cytological Techniques/*standards, Devine M, Diagnostic, Giant Cells/pathology, Helms S E, Herpes Simplex/*diagnosis/pathology, Humans, Microscopy, Reagent Kits

Characterization of the early events in vitamin C and K3-induced death of human bladder tumor cells.

Cardiomyocyte aging and hypertrophy: atrial and ventricular changes in normal and myopathic Syrian hamsters.

Cardiac eccentric hypertrophy is associated with complex architectural and metabolic alterations. Atrial and ventricular myocyte diameters in cardiomyopathic (Bio 14.6) and age-matched control (F1b) Syrian hamsters were compared and histopathology…

Tags: 1990, Aging/*pathology, Animals, Bissler J J, Cardiomegaly/*pathology, Cricetinae, Electron, Female, Gilloteaux J, Heart Atria/pathology/ultrastructure, Heart Ventricles/pathology/ultrastructure, Jarjoura D, Journal of submicroscopic cytology and pathology, Kondolios P, Mesocricetus, Microscopy, Myocardium/*cytology/pathology/ultrastructure

Epithelial surface changes and induction of gallstones in the male Syrian hamster gallbladder as a result of a two-month sex steroid treatment.

Transmission (TEM) and scanning (SEM) electron microscopic observations were correlated to characterize morphologic changes induced in the gallbladder of male Syrian hamsters following a two-month estradiol (E) and estradiol + medroxyprogesterone (E…

Light and electron microscopical immunolocalization of neuropeptide Y-containing nerves in the hamster gallbladder.

Neuropeptide Y (NPY)-containing nerve structures were detected in the Syrian hamster gallbladder by using peroxidase-antiperoxidase immunohistochemical staining and immunoelectron microscopic techniques. In addition, Alcian blue-P.A.S. was used to…

Scanning electron microscopy and transmission electron microscopy aspects of synergistic antitumor activity of vitamin C - vitamin K3 combinations against human prostatic carcinoma cells.

A MTT/formazan assay was used to evaluate the antitumor activity of vitamin C (Vit C), vitamin K3 (Vit K3), or vitamin C:vitamin K3 combinations against a human prostatic carcinoma cell line (DU145). Both Vit C and Vit K3 alone exhibited antitumor…

Browse Items (63 total)