Browse Items · NEOMED Bibliography Database

Ethics and micromanaged care.

The ethical foundation on which my medical practice is based was recently shaken by an episode involving the intrusion of managed care into my practice. With the patient's informed consent, I prescribed a medication that I knew would not work.

Accuracy and efficacy of nuclear scintigraphy for the detection of gastrointestinal bleeding.

OBJECTIVES: To determine the accuracy and cost-effectiveness of nuclear scintigraphy for the diagnosis and localization of gastrointestinal (GI) bleeding and to determine whether nuclear scintigraphy accurately predicts the results of angiography.…

Tags: 1997, 80 and over, Abdu R A, Adult, Aged, Archives of surgery (Chicago, Ill. : 1960), Garofalo T E, Gastrointestinal Hemorrhage/*diagnostic imaging, Humans, Middle Aged, Predictive Value of Tests, Radionuclide Imaging, Reproducibility of Results, Retrospective Studies

Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011.

IMPORTANCE: The National Action Plan for Combating Antibiotic-Resistant Bacteria set a goal of reducing inappropriate outpatient antibiotic use by 50% by 2020, but the extent of inappropriate outpatient antibiotic use is unknown. OBJECTIVE: To…

Tags: 2016, Adolescence, Adolescent, Adult, Aged, Ambulatory Care – Statistics and Numerical Data, Ambulatory Care/*statistics & numerical data, Anti-Bacterial Agents/*therapeutic use, Antibiotics – Therapeutic Use, Bartoces Monina, Child, Department of Internal Medicine, Enns Eva A, Female, File Thomas M Jr, Finkelstein Jonathan A, Fleming-Dutra Katherine E, Gerber Jeffrey S, Health Care Surveys, Hersh Adam L, Hicks Lauri A, Human, Humans, Hyun David Y, Inappropriate Prescribing – Statistics and Numerical Data, Inappropriate Prescribing/*statistics & numerical data, Infant, JAMA, Linder Jeffrey A, Lynfield Ruth, Male, Margolis David J, May Larissa S, Merenstein Daniel, Metlay Joshua P, Middle Age, Middle Aged, NEOMED College of Medicine, Newborn, Newland Jason G, Otitis Media, Otitis Media – Drug Therapy, Pharyngitis – Drug Therapy, Pharyngitis/drug therapy, Physicians'/*statistics & numerical data, Piccirillo Jay F, Practice Patterns, Preschool, Prevalence, Respiratory Tract Infections – Drug Therapy, Respiratory Tract Infections/drug therapy, Roberts Rebecca M, Sanchez Guillermo V, Shapiro Daniel J, Suda Katie J, Suppurative/*drug therapy, Surveys, Thomas Ann, United States, Woo Teri Moser, Zetts Rachel M

Recognition of leukemia in skeletal remains: report and comparison of two cases.

Recognition of disease in the archeologic record is facilitated by characterization of the skeletal impact of documented (in life) disease. The present study describes the osteological manifestations of leukemia as identified in the skeletons of two…

Clues potentially distinguishing lytic lesions of multiple myeloma from those of metastatic carcinoma.

This study was conducted to determine whether individual bony lesions are specific for recognizing multiple myeloma and thereby distinguish it from metastatic cancer and leukemia. The lytic skeletal lesions of multiple myeloma are characterized by…

Tags: *Paleopathology, 1998, American journal of physical anthropology, Diagnosis, Differential, Dutour O, Female, Hershkovitz I, Humans, Leukemia/*pathology, Male, Middle Aged, Multiple Myeloma/*pathology, Neoplasm Metastasis/*pathology, Rothschild B M

Ultrastructural aspects of human gallbladder epithelial cells in cholelithiasis: production of anionic mucus.

The surface epithelium of 28 gallbladders removed during elective cholecystectomies and pathology collection was studied ultrastructurally. Focusing on 10 of the 28 cases that were diagnosed as cholecystitis, we found that the epithelium displayed…

Age-related size reduction of foramina in the cribriform plate.

Anecdotal evidence suggests that the foramina of the cribriform plate which transmit cranial nerve I decrease in size with age, but this finding has never been supported with quantitative data. It has also been observed that olfactory function…

Survey of cadaveric donors to a body donation program: 1978-1993.

Body donation files from the Department of Anatomy at Northeastern Ohio Universities College of Medicine were reviewed from the 569 donors used in our program from 1978-1993. The data were entered into a computerized database to evaluate the…

Survey of cadaveric donor application files: 1978-1993.

Information derived from application files of potential cadaveric donors to our body donation program from the period of 1978-1993 was entered into a customized database to assess the characteristics of people contributing to such a program. A total…

Antigenic stimulation and multiple myeloma. A prospective study.

BACKGROUND: A causal relationship between antigenic conditions and multiple myeloma was suggested by case reports. Although controlled studies identified associations with individual conditions, they failed to give overall support to the hypothesis.…

Pseudogout following intraarticular injection of sodium hyaluronate.

Tags: 1998, Altawil B, Arthritis and rheumatism, Chondrocalcinosis/*chemically induced, Contraindications, Humans, Hyaluronic Acid/*adverse effects, Injections, Intra-Articular, Knee Joint/drug effects/physiopathology, Luzar M J, Male, Middle Aged, Osteoarthritis/*drug therapy, Pain/drug therapy

Skeletal clues apparently distinguishing Waldenstrom's macroglobulinemia from multiple myeloma and leukemia.

This study was conducted to characterize macroscopically and by conventional radiography the bony lesions in a case of Waldenstrom's macroglobulinemia and to compare and contrast it with those of the other major hematologic lymphoproliferative…

Tags: 2002, American journal of human biology : the official journal of the Human Biology Council, Bone and Bones/diagnostic imaging/*pathology, Diagnosis, Differential, Humans, Leukemia/*diagnosis/pathology, Male, Middle Aged, Multiple Myeloma/*diagnosis/pathology, Radiography, Rothschild B M, Rothschild C, Ruhli F, Waldenstrom Macroglobulinemia/*diagnosis/pathology

A comparison of the full and short versions of the Arthritis Impact Measurement Scales.

This study examined the validity and reliability of full and short versions of the Arthritis Impact Measurement Scales (AIMS). One hundred fifty-five patients with Rheumatoid Arthritis followed at a University Hospital Rheumatology Clinic completed…

Tags: *Disability Evaluation, *Severity of Illness Index, 1991, Abraham N, Activities of Daily Living, Adult, Aged, Alarcon G S, Arthritis, Arthritis care and research : the official journal of the Arthritis Health Professions Association, Austin J S, Bradley L A, Female, Humans, Lorish C D, Male, Middle Aged, Reproducibility of Results, Rheumatoid/*diagnosis/rehabilitation

MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes.

OBJECTIVE: Hedgehog (HH) signaling has recently been associated with cartilage degradation in osteoarthritis (OA). Because interleukin-1beta (IL-1beta) has been implicated as a principal instigator of OA, we sought to determine whether

Tags: 2015, Academic Medical Centers, Aged, Akhtar Nahid, Analysis of Variance, Animal, Animals, Anterior Cruciate Ligament/surgery, Arthritis & rheumatology (Hoboken, N.J.), Blotting, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism/pathology, Cultured, Department of Anatomy & Neurobiology, Disease Models, Female, Funding Source, Gene Expression Regulation/genetics/*physiology, Haqqi Tariq M, Hedgehog Proteins/genetics/*metabolism, HEK293 Cells, Human, Humans, Immunohistochemistry, In Vitro Techniques, Interleukin-1beta/pharmacology, Knee/etiology/*metabolism/pathology, Makki Mohammad S, Male, Matrix Metalloproteinase 13/metabolism, MicroRNAs/genetics/*metabolism, Middle Age, Middle Aged, NEOMED College of Medicine, Ohio, Open Reading Frames/genetics/*physiology, Osteoarthritis, Osteoarthritis – Epidemiology, Osteoarthritis – Physiopathology, Polymerase Chain Reaction, Rabbits, Signal Transduction/genetics/physiology, T-Tests, Transfection, Up-Regulation/drug effects/genetics/physiology, Western

MicroRNA-9 promotion of interleukin-6 expression by inhibiting monocyte chemoattractant protein-induced protein 1 expression in interleukin-1beta-stimulated human chondrocytes.

OBJECTIVE: Enhanced expression of interleukin-6 (IL-6) plays an important role in the pathogenesis of osteoarthritis (OA). Monocyte chemoattractant protein-induced protein 1 (MCPIP-1) is a novel posttranscriptional regulator of IL-6 expression and is…

Tags: 2015, Academic Medical Centers, Aged, Arthritis & rheumatology (Hoboken, N.J.), Articular/drug effects/*metabolism, Cartilage, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism, Cultured, Department of Anatomy & Neurobiology, Enzyme-Linked Immunosorbent Assay, Funding Source, Gene Knockdown Techniques, Haqqi Tariq M, Haseeb Abdul, Hip/*genetics/metabolism, Human, Humans, Immunoblotting – Utilization, Immunoprecipitation, Interleukin-1beta/pharmacology, Interleukin-6/*genetics/metabolism, Interleukins – Physiology, Makki Mohammad S, Messenger/drug effects/*metabolism, MicroRNAs/drug effects/*genetics/metabolism, Middle Aged, NEOMED College of Medicine, Ohio, Osteoarthritis, Osteoarthritis – Complications, Osteoarthritis – Physiopathology, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleases/drug effects/*genetics/metabolism, RNA, T-Tests, Transcription Factors/drug effects/*genetics/metabolism

Images in cytology. Fine-needle aspiration of a lumbar chordoma.

Tags: 2010, Biopsy, Chordoma/diagnosis/*pathology, Diagnosis, Diagnostic cytopathology, Differential, Female, Fine-Needle, Ganesan Santhi, Humans, Immunohistochemistry, Lumbar Vertebrae/*pathology, Middle Aged, Moonda Afreen H

Phase II study of gefitinib in patients with advanced salivary gland cancers.

BACKGROUND: The purpose of this study was to determine the antitumor activity of the epidermal growth factor receptor (EGFR) inhibitor gefitinib in patients with recurrent/metastatic salivary gland cancer. METHODS: We conducted a phase II study in…

Tags: 2015, 80 and over, Adenocarcinoma/drug therapy/mortality/pathology, adenoid cystic carcinoma, Adenoid Cystic/*drug therapy/mortality/pathology, Adult, Aged, Antineoplastic Agents/*therapeutic use, Blumenschein George R Jr, Carcinoma, Department of Internal Medicine, Disease-Free Survival, Dose-Response Relationship, Drug, Drug Administration Schedule, El-Naggar Adel K, Female, Gefitinib, Glisson Bonnie S, Gonzalez-Angulo Ana M, Head & neck, Humans, Jakob John A, Kies Merrill S, Kupferman Michael E, Lee J Jack, Liu Diane D, Local/*drug therapy/mortality/pathology, Male, Maximum Tolerated Dose, Middle Aged, NEOMED College of Medicine, Neoplasm Invasiveness/pathology, Neoplasm Recurrence, Neoplasm Staging, non-adenoid cystic carcinoma, Prognosis, Quinazolines/*therapeutic use, Remission Induction, response to therapy, salivary gland cancer, Salivary Gland Neoplasms/*drug therapy/mortality/pathology, Survival Analysis, Treatment Outcome

Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.

The gene encoding cholesterol 7alpha-hydroxylase (CYP7A1) is tightly regulated to control bile acid synthesis and maintain lipid homeostasis. Recent studies in mice suggest that bile acid synthesis is regulated by the fasted-to-fed cycle, and fasting…

Evaluation of indicated non-cosmetic panniculectomy at time of gynecologic surgery.

OBJECTIVE: To report postoperative outcomes among patients undergoing indicated non-cosmetic panniculectomy at the time of gynecologic surgery. METHODS: Medical charts were retrospectively reviewed for patients who underwent panniculectomy coupled…

Tags: *Abdominoplasty/adverse effects, *Gynecologic Surgical Procedures/adverse effects, 2017, 80 and over, Abdominal/*surgery, Abdominoplasty – Adverse Effects, Adipose Tissue – Surgery, Adult, Aged, Body Mass Index, Female, Female – Complications, Female – Surgery, Female/complications/*surgery, Genital Diseases, Gynecologic – Adverse Effects, Gynecologic surgery, Hopkins Michael P, Humans, Infection, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, Middle Age, Middle Aged, Obesity, Obesity – Complications, Obesity – Surgery, Obesity/complications/*surgery, Panniculectomy, Patibandla Jay R, Rasmussen Ryan W, Retrospective Design, Retrospective Studies, Risk Factors, Subcutaneous Fat, Surgery, Surgical Wound Infection – Etiology, Surgical Wound Infection/*etiology, Wound complication, Wound Healing

Sucrose, But Not Glucose, Blocks IL1-beta-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway.

Pathogenesis of osteoarthritis (OA) is multifactorial but interleukin-1beta (IL-1beta) is known to be an important mediator of cartilage degradation. Autophagy is an essential cellular homeostasis mechanism and has been proposed to protect against…

Evaluation of extended antibiotic prophylaxis in patients undergoing indicated non-cosmetic panniculectomy at the time of gynecologic surgery.

BACKGROUND: Panniculectomy at time of gynecologic surgery is used to improve visualization and prevent major complications in morbidly obese patients. We examine the role of extended antibiotic prophylaxis in prevention of surgical site infections…

Agreement Between an Automated Volume Breast Scanner and Handheld Ultrasound for Diagnostic Breast Examinations.

OBJECTIVES: To compare the agreement and interobserver variability of diagnostic handheld ultrasound (US) and a single volume on an automated breast volume scanner (ABVS) and to determine whether there was a significant difference if the ABVS was…

Quantitative skin assessment using spatial frequency domain imaging (SFDI) in patients with or at high risk for pressure ulcers.

BACKGROUND AND OBJECTIVE: Pressure ulcers (PU) are a significant problem facing the health system in the United States. Here, we present preliminary case studies demonstrating feasibility of Spatial Frequency Domain Imaging (SFDI) to assess skin…

Gender differences in the association between antidepressant use and restless legs syndrome.

Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary…

Prevalence and Predictors of Metformin Prescribing in Adults with Type 2 Diabetes Mellitus: A National Cross-Sectional Study.

OBJECTIVE: Metformin is the first-line oral type 2 diabetes treatment. Despite an abundance of evidence, metformin is routinely underused. This study evaluated the rates of metformin use in an appropriate outpatient type 2 diabetes population and…

Alternative medicine in gynecologic oncology: A case report.

A patient with Stage IIB squamous cell cancer of the cervix presented 10 days into her primary radiation therapy with neutropenic fever and diarrhea requiring hospitalization and delay in treatment. The patient's history revealed extensive use of…

Tags: *Complementary Therapies, 2000, Carcinoma, Diarrhea/*etiology, Female, Fever/*etiology, Gynecologic oncology, Hopkins M P, Hospitalization, Humans, Medical History Taking, Medicinal/*adverse effects, Middle Aged, Neutropenia/*etiology, Plants, Squamous Cell/drug therapy/*radiotherapy, Time Factors, Uterine Cervical Neoplasms/drug therapy/*radiotherapy, von Gruenigen V E

Metastatic carcinoma of the spine with neurologic complications: an autopsy review.

We conducted post-mortem examinations on 12 patients who had documented metastatic carcinoma to the spine with attendant neurologic complications. The examinations were studied to determine the location of the metastatic lesion in relation to the…

Tags: 1993, Adult, Aged, Autopsy, Female, Humans, Leeson M C, Male, Middle Aged, Orthopedics, Spinal Cord Compression/*etiology/pathology, Spinal Neoplasms/*complications/pathology/*secondary, Zechmann J P

The cost of laparoscopic versus open cholecystectomy in a community hospital.

This retrospective study reviewed the hospital and professional costs, charges, and reimbursements for laparoscopic cholecystectomy (lap chole) and open cholecystectomy (open chole) and compared the two procedures. There was no significant difference…

Laparoscopic hernia repair. Three-year experience.

The basis of laparoscopic transabdominal preperitoneal repair (LTPR) of herniae rests upon the utilization of a prosthetic screen to cover hernia defects. Preperitoneal prosthetic screen interposition reproduces the effect of the inguinal shutter…

Tags: 1995, 80 and over, Adolescent, Adult, Aged, Female, Follow-Up Studies, Hernia, Humans, Inguinal/*surgery, Kavic M S, Laparoscopy/*methods, Male, Middle Aged, Postoperative Complications, Prostheses and Implants, Reoperation, Surgical endoscopy

Recognition of depression by internal medicine residents.

We studied the ability of internal medicine residents to recognize depressive symptoms in a population of lower socio-economic primary care patients. Four hundred twenty patients completed the short form of the Beck Depression Inventory (BDI).…

Rectal trauma and associated hemorrhage with the use of the ConvaTec Flexi-Seal fecal management system: report of 3 cases.

The management of fecal incontinence is a struggle to maintain patient hygiene and limit the transmission of nosocomial infections. Intrarectal devices that cause diversion and collection of the fecal stream have been used with increasing frequency.…

Tags: 2010, Aged, Catheterization/*adverse effects/*instrumentation, Chase Daniel, Coughlin Lisa, Diseases of the colon and rectum, Fecal Incontinence/*therapy, Female, Gastrointestinal Hemorrhage/*etiology/surgery, Heaton Bren, Hemostasis, Humans, Male, Metha Jeet, Middle Aged, Pressure Ulcer/*etiology/surgery, Rectum/*injuries/surgery, Sparks Dorothy, Surgical/methods

Acquired inhibitor to factor VIII in small cell lung cancer: a case report and review of the literature.

Acquired hemophilia (antibodies or inhibitors to factor VIII) is the most common acquired disease affecting clotting factors. It has been described in association with autoimmune disease, malignancy, dermatologic disorders, in the postpartum period,…

Tags: 2001, Ahmed F, Annals of hematology, Carcinoma, Crock R, Department of Internal Medicine, Factor VIII/*antagonists & inhibitors, Humans, Lara L, Lung Neoplasms/*chemistry, Male, Middle Aged, NEOMED College of Medicine, Rutecki G W, Shwaiki A, Small Cell/*chemistry, Whittier F C

No rheumatoid arthritis in ancient Egypt: a reappraisal.

Antiquity of rheumatoid arthritis (RA) remains controversial, and its origins in Americas or in the Old World are disputed. Proponents of the latter frequently refer to RA in ancient Egypt, but validity of those claims has never been examined. Review…

Vaginal leiomyoma co-existing with broad ligament and multiple uterine leiomyomas.

A 48 year old African American woman presented with bladder pressure leading to the diagnosis of broad ligament and multiple uterine leiomyomas. She was also found to have a lateral vaginal wall mass which was confirmed to be a leiomyoma. Unlike…

Tags: *Neoplasms, 2001, Archives of gynecology and obstetrics, Fallopian Tubes/surgery, Female, Hecht B R, Hopkins M P, Humans, Hysterectomy, Leiomyoma/*diagnosis/pathology/surgery, Leiomyomatosis/*diagnosis/pathology/surgery, Meniru G I, Middle Aged, Multiple Primary, Onuora C O, Ovariectomy, Uterine Neoplasms/*diagnosis/pathology/surgery, Vaginal Neoplasms/*diagnosis/pathology/surgery, Wasdahl D

A unique case of ovarian psammocarcinoma with mediastinal, pulmonary, subcutaneous, and omental metastases.

Psammocarcinoma is a rare form of serous ovarian and peritoneal carcinoma, characterized by abundant psammoma bodies, invasiveness, and low-grade cytological features. Many of the cases which have been reported had extraovarian spread and peritoneal…

Appendicitis in the elderly: a change in the laparoscopic era.

BACKGROUND: Appendicitis in elderly patients is associated with significant morbidity and mortality. Early and correct diagnosis together with minimally invasive surgery can lead to more favorable outcomes than occurred in the prelaparoscopic era.…

Splenic rupture from colonoscopy. A report of two cases and review of the literature.

Splenic injury after colonoscopy is rare. Only 15 cases previously have been reported in the English literature. Partial capsular avulsion is the proposed mechanism of injury. Any condition causing increased splenocolic adhesions may be a…

Tags: 1997, Colonoscopy/*adverse effects, Espinal E A, Female, Follow-Up Studies, Hoak T, Humans, Middle Aged, Porter J A, Slezak F A, Spleen/injuries, Splenectomy, Splenic Rupture/*etiology/surgery, Surgical endoscopy, Tomography, X-Ray Computed

Revisiting classification of pain from bone metastases as mild, moderate, or severe based on correlation with function and quality of life.

PURPOSE: The objective of our study was to determine the optimal cut points for classification of pain scores as mild, moderate, and severe based on interference with function and quality of life (QOL). METHODS: We evaluated 822 patients who…

Tags: *Quality of Life, *Severity of Illness Index, 2016, 80 and over, Adolescence, Adolescent, Adult, Aged, Babington Scott, Bone metastases, Bone Neoplasms, Bone Neoplasms – Complications, Bone Neoplasms/*complications/secondary, Brief pain inventory, Brundage Michael, Chow Edward, Demas William F, Ding Keyue, Female, Functional interference, Funding Source, Hartsell William F, Hoskin Peter, Human, Humans, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, Ong Francisca, Pain – Classification, Pain – Etiology, Pain Measurement – Methods, Pain Measurement/*methods, Pain severity, Pain/*classification/etiology, Parulekar Wendy R, Quality of Life, Questionnaires, Re-irradiation, Roos Daniel, Severity of Illness Indices, Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, Survival, van der Linden Yvette M, van Tienhoven Geertjan, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y, Young Adult, Zhu Liting

Identification of plasma microRNA expression profile in radiographic axial spondyloarthritis-a pilot study.

At present, there are no studies that have established a microRNA (miRNA)-based signature profile in patients with radiographic axial spondyloarthritis (rad-axial SpA), and we hypothesized that these patients may have aberrantly expressed circulating…

Complete remission in a patient with metastatic mixed adenocarcinoma/extrapulmonary small cell carcinoma of the prostate.

Approximately 10% of all extra-pulmonary small cell carcinoma (EPSCC) arises in the prostate either as de novo mixed adenocarcinoma with small cell components or a pure small cell carcinoma. Extensive disease carries a median survival of about 10…

Tags: 2011, Adenocarcinoma/diagnosis/*secondary, Androgen Antagonists/therapeutic use, Bone Neoplasms/*drug therapy/*secondary, Brammer Jonathan Edward, Carcinoma, Cisplatin/therapeutic use, Combined Modality Therapy, Etoposide/therapeutic use, Humans, International journal of clinical oncology, Lulla Premal, Lung Neoplasms/diagnosis/*secondary, Lynch Garrett Rush, Male, Middle Aged, Prostatic Neoplasms/*drug therapy/metabolism/*pathology, Remission Induction, Small Cell/diagnosis/*secondary

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