Browse Items · NEOMED Bibliography Database

Electrical stimuli patterned after the theta-rhythm induce multiple forms of LTP.

The induction of long-term potentiation (LTP) by high-frequency stimulation is considered an acceptable model for the study of learning and memory. In area CA1 calcium influx through N-methyl-D-aspartate receptors (NMDARs; nmdaLTP) and/or

VDCCs and NMDARs underlie two forms of LTP in CA1 hippocampus in vivo.

N-methyl-D-aspartate receptor/channel (NMDAR) and voltage-dependent calcium channel (VDCC) antagonists applied independently reduce the magnitude of long-term potentiation (LTP) in area CA1 of the hippocampal slice preparation. When used in…

Tags: 1999, Animals, Calcium Channel Blockers/*pharmacology, Dizocilpine Maleate/pharmacology, Excitatory Amino Acid Antagonists/*pharmacology, Excitatory Postsynaptic Potentials/drug effects, Hippocampus/*drug effects, Journal of neurophysiology, Long-Evans, Long-Term Potentiation/*drug effects, Male, Membrane Potentials/physiology, Morgan S L, N-Methyl-D-Aspartate/*antagonists & inhibitors, Rats, Receptors, Teyler T J, Verapamil/pharmacology

Synaptic plasticity and secondary epileptogenesis.

Tags: 2001, Animals, Epilepsy/etiology/*physiopathology, Humans, International review of neurobiology, Long-Term Potentiation/physiology, Morgan S L, Neuronal Plasticity/*physiology, Russell R N, Synapses/*physiology, Teyler T J, Woodside B L

Epileptic-like activity induces multiple forms of plasticity in hippocampal area CA1.

Mesial temporal lobe epilepsy is a relatively common form of epilepsy that afflicts many thousands of people. It has been suggested that the development of primary and secondary foci may involve mechanisms similar to long-term potentiation (LTP). In…

Tags: *Neuronal Plasticity, 2001, Animals, Brain research, Calcium Channels, Electrophysiology, Epilepsy/chemically induced/*physiopathology, Hippocampus/*physiopathology, Ion Channels/physiology, L-Type/physiology, Long-Evans, Long-Term Potentiation/physiology, Morgan S L, N-Methyl-D-Aspartate/metabolism, Potassium Chloride, Rats, Receptors, Synapses/physiology, Teyler T J

Depotentiation of vdccLTP requires NMDAR activation.

Long-term potentiation is an enduring increase in synaptic efficacy following repeated stimulation of afferent fibers that is thought to underlie memory. In area CA1 of the hippocampus at least two forms of synaptic potentiation coexist at the same…

Browse Items (5 total)

Electrical stimuli patterned after the theta-rhythm induce multiple forms of LTP.

VDCCs and NMDARs underlie two forms of LTP in CA1 hippocampus in vivo.

Synaptic plasticity and secondary epileptogenesis.

Epileptic-like activity induces multiple forms of plasticity in hippocampal area CA1.

Depotentiation of vdccLTP requires NMDAR activation.