1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0002-8703(95)90064-0" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0002-8703(95)90064-0</a>
Pages
685–691
Issue
4
Volume
130
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Prediction of cardiac death in patients with a very low ejection fraction after myocardial infarction: a Cardiac Arrhythmia Suppression Trial (CAST) study.
Publisher
An entity responsible for making the resource available
American heart journal
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
1995-10
Subject
The topic of the resource
*Stroke Volume; Blood Pressure; Heart Arrest/mortality; Heart Rate; Humans; Left/*mortality/physiopathology; Multicenter Studies as Topic; Myocardial Infarction/drug therapy/*mortality/physiopathology; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk Factors; Thrombolytic Therapy; Ventricular Dysfunction
Creator
An entity primarily responsible for making the resource
Josephson R A; Chahine R A; Morganroth J; Anderson J; Waldo A; Hallstrom A
Description
An account of the resource
The Cardiac Arrhythmia Suppression Trial (CAST) database was analyzed with a Cox proportional hazards regression model to predict the mortality of patients with very poor left ventricular systolic function (ejection fraction \textless or = .20). Predictors of total death or cardiac arrest were (relative risk), QRS duration (1.10/10 msec increase), coronary artery bypass grafting (0.38), basal heart rate (1.26/10 min-1 increase), diastolic blood pressure (0.79/10 mm Hg increase), diabetes mellitus (1.59), EF (0.94/1 U increase), and ease of suppression (the ability to suppress ambient ventricular ectopy on the lowest dose of the first randomly chosen CAST drug) (0.64). Predictors of arrhythmic death or arrhythmic cardiac arrest included thrombolysis (0.44), coronary artery bypass grafting (0.38), diuretic use (1.71), heart rate (1.21/10 min-1 increase), calcium channel blocker use (1.69), and QRS duration (1.10/10 msec increase). Thus easily measurable clinical and laboratory variables help predict prognosis in this clinically important subgroup. The pathophysiologic basis for and the clinical implications of the ease of ventricular arrhythmia suppression correlating with prognosis requires further study.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0002-8703(95)90064-0" target="_blank" rel="noreferrer noopener">10.1016/0002-8703(95)90064-0</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Stroke Volume
1995
American heart journal
Anderson J
Blood Pressure
Chahine R A
Department of Internal Medicine
Hallstrom A
Heart Arrest/mortality
Heart Rate
Humans
Josephson R A
Left/*mortality/physiopathology
Morganroth J
Multicenter Studies as Topic
Myocardial Infarction/drug therapy/*mortality/physiopathology
NEOMED College of Medicine
Prognosis
Proportional Hazards Models
Randomized Controlled Trials as Topic
Risk Factors
Thrombolytic Therapy
Ventricular Dysfunction
Waldo A