1
40
4
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1136/bjophthalmol-2014-305915" target="_blank" rel="noreferrer noopener">http://doi.org/10.1136/bjophthalmol-2014-305915</a>
Pages
471–476
Issue
4
Volume
99
Dublin Core
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Title
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Topical brinzolamide (Azopt) versus placebo in the treatment of infantile nystagmus syndrome (INS).
Publisher
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The British journal of ophthalmology
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
2015-04
Subject
The topic of the resource
Administration; Adult; Aged; Binocular/physiology; Carbonic Anhydrase Inhibitors/*therapeutic use; Clinical Trial; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscles; Nystagmus; Ophthalmic Solutions; Pathologic/*drug therapy/physiopathology; Prospective Studies; Sulfonamides/*therapeutic use; Thiazines/*therapeutic use; Topical; Treatment Medical; Vision; Visual Acuity/physiology
Creator
An entity primarily responsible for making the resource
Hertle Richard W; Yang Dongsheng; Adkinson Tonia; Reed Michael
Description
An account of the resource
PURPOSE: To test the hypothesis that the topical carbonic anhydrase inhibitor brinzolamide (Azopt) has beneficial effects versus placebo on measures of nystagmus and visual acuity in adult subjects with infantile nystagmus syndrome (INS). DESIGN: Prospective, cross-over, double masked clinical trial. METHODS: SETTING: Single centre. STUDY POPULATION: Five subjects \textgreater/=18 years old with typical INS and best-binocular visual acuity in their primary position null zone ETDRS 55 letters to 85 letters (20/200 to 20/50) and had no previous treatment for nystagmus. INTERVENTION: In a randomised order, each subject received one drop of Azopt or placebo in both eyes three times a day separated by a washout period of at least a week followed by Azopt or placebo in both eyes three times a day; thus each subject got the drug and placebo, each acting as his or her own control. OUTCOME MEASURES: The nystagmus acuity function and INS waveforms obtained from eye movement recordings, binocular optotype visual acuity, using the ETDRS protocol analysed individually and as a group before and after Azopt and placebo. RESULTS: Versus placebo and baseline measures, topical Azopt significantly improved; INS waveform characteristics in the primary position null zone, group mean values of the nystagmus acuity function across gaze (p\textless0.01) and group mean ETDRS binocular letter visual acuity (p\textless0.05). There was a predictable decrease in intraocular pressure (IOP) without any systemic or ocular adverse events. CONCLUSIONS: Although a prospective large-scale clinical trial is needed to prove effectiveness, an eye-drop-based therapy for INS may emerge as a viable addition to optical, surgical, behavioural and systemic drug therapies for INS. TRIAL REGISTRATION NUMBER: NCT01312402.
Identifier
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<a href="http://doi.org/10.1136/bjophthalmol-2014-305915" target="_blank" rel="noreferrer noopener">10.1136/bjophthalmol-2014-305915</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2015
Adkinson Tonia
Administration
Adult
Aged
Binocular/physiology
Carbonic Anhydrase Inhibitors/*therapeutic use
Clinical Trial
Cross-Over Studies
Double-Blind Method
Female
Hertle Richard W
Humans
Male
Middle Aged
Muscles
Nystagmus
Ophthalmic Solutions
Pathologic/*drug therapy/physiopathology
Prospective Studies
Reed Michael
Sulfonamides/*therapeutic use
The British journal of ophthalmology
Thiazines/*therapeutic use
Topical
Treatment Medical
Vision
Visual Acuity/physiology
Yang Dongsheng
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.4202/app.00119.2014" target="_blank" rel="noreferrer noopener">http://doi.org/10.4202/app.00119.2014</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
125-134
Issue
1
Volume
61
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Dublin Core
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Title
A name given to the resource
Pathological phalanges in a camarasaurid sauropod dinosaur and implications on behaviour
Publisher
An entity responsible for making the resource available
Acta Palaeontologica Polonica
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016
Subject
The topic of the resource
bone; bone tumour; camarasaurids; degenerative joint disease; Dinosauria; entheses; enthesophytes; histology; Jurassic; life-style; morphology; Morrison Formation; muscles; osteoarthritis; osteoblastoma; osteochondrosis; osteoid osteoma; Paleontology; paleopathology; Sauropoda; tendon; USA; Wyoming
Creator
An entity primarily responsible for making the resource
Tschopp E; Wings O; Frauenfelder T; Rothschild B M
Description
An account of the resource
Several types of pathological bony overgrowth are known from various dinosaur taxa but, except for stress fractures, are rarely reported from appendicular elements. Herein we describe pathological manual and pedal phalanges of a camarasaurid sauropod (SMA 0002), which show features rarely recognised in non-avian dinosaurs. They include lateral osteophytes and smoothing of phalangeal articular surfaces, a deep pit, proximal enthesophytes in pedal unguals, distal overgrowth associated with a fracture, and a knob-like overgrowth lateral to the distal condyles of a pedal phalanx. Their causes were assessed by means of visual examination, CT scans, and bone histology, where possible. The lateral osteophytes are interpreted as symptoms of osteoarthritis. The ossified tendon insertions in the unguals are most probably the result of prolonged, heavy use of the pedal claws, possibly for scratch-digging. The distal overgrowth is interpreted to have developed due to changed stress regimes, and to be the cause for the fracture. The deep pit represents most likely a case of osteochondrosis, whereas the knob-like overgrowth likely represents a post-traumatic phenomenon not previously reported in dinosaurs. The study confirms that a rigorous assessment of pathologies can yield information about behaviour in long-extinct animals.
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<a href="http://doi.org/10.4202/app.00119.2014" target="_blank" rel="noreferrer noopener">10.4202/app.00119.2014</a>
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The file format, physical medium, or dimensions of the resource
Journal Article
2016
Acta Palaeontologica Polonica
Bone
bone tumour
camarasaurids
degenerative joint disease
Dinosauria
entheses
enthesophytes
Frauenfelder T
histology
Journal Article
Jurassic
life-style
morphology
Morrison Formation
Muscles
Osteoarthritis
osteoblastoma
OSTEOCHONDROSIS
osteoid osteoma
Paleontology
Paleopathology
Rothschild B M
Sauropoda
tendon
Tschopp E
USA
Wings O
Wyoming
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<table width="91" style="border-collapse:collapse;width:408px;"><colgroup><col width="91" style="width:68pt;" /></colgroup><tbody><tr style="height:15pt;"><td width="91" height="20" class="xl18" style="width:68pt;height:15pt;"><a href="http://doi.org/10.1016/B978-0-12-818969-6.00010-8">http://doi.org/10.1016/B978-0-12-818969-6.00010-8</a></td>
</tr></tbody></table>
Pages
137-149
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Anatomy & Neurobiology
Update Year & Number
Jan to Aug list 2021
Dublin Core
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Title
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Chapter 10 - Postcranial skeleton and musculature
Creator
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Thewissen JGM; Hillmann DJ; George JC; Tarpley RJ; Sheffield Gay; Stimmelmayr R; Suydam RS
Publisher
An entity responsible for making the resource available
The Bowhead Whale
Date
A point or period of time associated with an event in the lifecycle of the resource
2021
Description
An account of the resource
The postcranial skeleton of bowhead whales was described in detail more than 100 years ago. The musculature of bowheads has not been studied in detail but matches that of other mysticetes in general features. In this chapter, we focus on some aspects of the skeleton that differs from that of other cetaceans. First, the skeleton of bowheads changes with ontogenetic age. Some of these changes are gross-morphologically, while others are biochemical and histological. Several are related to the life history of the species. Our discussion focuses on the changes in the morphology of the cervical vertebral column, the ontogenetic variation in carpals, and the variation in the hind limb. Individuals with external hind limbs occur infrequently, but there is a great variation in the size of ox coxae, femur, and tibia.
Identifier
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<table width="91" style="border-collapse:collapse;width:405px;"><colgroup><col width="91" style="width:68pt;" /></colgroup><tbody><tr style="height:15pt;"><td width="91" height="20" class="xl18" style="width:68pt;height:15pt;"><a href="http://doi.org/10.1016/B978-0-12-818969-6.00010-8">http://doi.org/10.1016/B978-0-12-818969-6.00010-8</a></td>
</tr></tbody></table>
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Elsevier has partnered with Copyright Clearance Center's RightsLink service to offer a variety of options for reusing this content.
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Book Chapter
2021
Balaena mysticetus
bowhead whale
Forelimb
hindlimb
Muscles
myology
Skeleton
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/B978-0-12-818969-6.00010-8" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/B978-0-12-818969-6.00010-8</a>
Pages
137-149
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1016/B978-0-12-818969-6.00010-8" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1016/B978-0-12-818969-6.00010-8</a>
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Update Year & Number
January 2021 List
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Anatomy & Neurobiology
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Chapter 10 - Postcranial skeleton and musculature
Publisher
An entity responsible for making the resource available
The Bowhead Whale
Date
A point or period of time associated with an event in the lifecycle of the resource
2021
2021-01-01
Subject
The topic of the resource
forelimb; myology; Bowhead whale; muscles; skeleton; Balaena mysticetus; hindlimb;
Creator
An entity primarily responsible for making the resource
Thewissen JGM; Hillmann DJ; George JC; Tarpley RJ; Sheffield Gay; Stimmelmayr R; Suydam RS
Description
An account of the resource
The postcranial skeleton of bowhead whales was described in detail more than 100 years ago. The musculature of bowheads has not been studied in detail but matches that of other mysticetes in general features. In this chapter, we focus on some aspects of the skeleton that differs from that of other cetaceans. First, the skeleton of bowheads changes with ontogenetic age. Some of these changes are gross-morphologically, while others are biochemical and histological. Several are related to the life history of the species. Our discussion focuses on the changes in the morphology of the cervical vertebral column, the ontogenetic variation in carpals, and the variation in the hind limb. Individuals with external hind limbs occur infrequently, but there is a great variation in the size of ox coxae, femur, and tibia.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/B978-0-12-818969-6.00010-8" target="_blank" rel="noreferrer noopener"></a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2021
Balaena mysticetus
bowhead whale
Department of Anatomy & Neurobiology
Forelimb
George JC
Hillmann DJ
hindlimb
January 2021 List
journalArticle
Muscles
myology
NEOMED College of Medicine
Sheffield Gay
Skeleton
Stimmelmayr R
Suydam RS
Tarpley RJ
The Bowhead Whale
Thewissen JGM