1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/(SICI)1098-1063(1998)8:4%3C373::AID-HIPO5%3E3.0.CO;2-I" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/(SICI)1098-1063(1998)8:4%3C373::AID-HIPO5%3E3.0.CO;2-I</a>
Pages
373–379
Issue
4
Volume
8
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
NMDA receptor-independent LTP in basal versus apical dendrites of CA1 pyramidal cells in rat hippocampal slice.
Publisher
An entity responsible for making the resource available
Hippocampus
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
1905-6
Subject
The topic of the resource
Animals; Calcium Channel Blockers/pharmacology; Dendrites/*physiology; Electric Stimulation; Enzyme Inhibitors/pharmacology; Genistein/pharmacology; Hippocampus/cytology/*physiology; In Vitro Techniques; Inbred Strains; Long-Term Potentiation/drug effects/*physiology; Male; N-Methyl-D-Aspartate/*physiology; Phenols/pharmacology; Protein-Tyrosine Kinases/antagonists & inhibitors; Pyramidal Cells/*physiology; Rats; Receptors; Verapamil/pharmacology
Creator
An entity primarily responsible for making the resource
Cavus I; Teyler T J
Description
An account of the resource
The ability of hippocampal CA1 basal synapses to express N-methyl-D-aspartate (NMDA) receptor-independent long-term potentiation (non-NMDA LTP) was studied and compared to the simultaneously induced apical dendritic non-NMDA LTP. Non-NMDA LTP in basal and apical dendrites was induced using stimulation pattern similar to the sharp wave-associated CA3 bursts. Basal dendritic non-NMDA LTP was input-specific and displayed similar development and magnitude to the apical dendritic non-NMDA LTP. Both apical and basal dendritic non-NMDA potentiations were inhibited by the voltage-dependent calcium channel (VDCC) inhibitor verapamil and the tyrosine kinase inhibitors genistein and levandustin A. However, the difference in the degree and time course of these inhibitions suggests involvement of distinct mechanisms in the two dendritic subfields.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/(SICI)1098-1063(1998)8:4%3C373::AID-HIPO5%3E3.0.CO;2-I" target="_blank" rel="noreferrer noopener">10.1002/(SICI)1098-1063(1998)8:4%3C373::AID-HIPO5%3E3.0.CO;2-I</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1998
Animals
Calcium Channel Blockers/pharmacology
Cavus I
Dendrites/*physiology
Electric Stimulation
Enzyme Inhibitors/pharmacology
Genistein/pharmacology
Hippocampus
Hippocampus/cytology/*physiology
In Vitro Techniques
Inbred Strains
Long-Term Potentiation/drug effects/*physiology
Male
N-Methyl-D-Aspartate/*physiology
Phenols/pharmacology
Protein-Tyrosine Kinases/antagonists & inhibitors
Pyramidal Cells/*physiology
Rats
Receptors
Teyler T J
Verapamil/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0306-4522(92)90072-a" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0306-4522(92)90072-a</a>
Pages
7–11
Issue
1
Volume
49
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
N-methyl-D-aspartate receptor-independent long-term potentiation in area CA1 of rat hippocampus: input-specific induction and preclusion in a non-tetanized pathway.
Publisher
An entity responsible for making the resource available
Neuroscience
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-07
Subject
The topic of the resource
2-Amino-5-phosphonovalerate/*pharmacology; Animals; Electron; Evoked Potentials/drug effects; Hippocampus/*physiology; In Vitro Techniques; Microscopy; N-Methyl-D-Aspartate/*physiology; N-Methylaspartate/*pharmacology; Pyramidal Tracts/drug effects/*physiology; Rats; Receptors; Time Factors
Creator
An entity primarily responsible for making the resource
Grover L M; Teyler T J
Description
An account of the resource
We previously reported that an N-methyl-D-aspartate receptor-independent component of long-term potentiation with an apparent delayed onset can be induced in area CA1 of the hippocampus. Here we show that some but not all of this delay in onset can be accounted for by a transient heterosynaptic depression. We also show that N-methyl-D-aspartate receptor-independent long-term potentiation is induced only in the input pathway tetanized, and not in a second pathway. However, prior induction of N-methyl-D-aspartate receptor-independent long-term potentiation in one pathway precludes later induction in an independent pathway. Calcium entry through dihydropyridine-sensitive Ca2+ channels may be a critical step for induction of N-methyl-D-aspartate receptor-independent long-term potentiation in area CA1 [Grover L. M. and Teyler T.J. (1990) Nature 347,
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0306-4522(92)90072-a" target="_blank" rel="noreferrer noopener">10.1016/0306-4522(92)90072-a</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
2-Amino-5-phosphonovalerate/*pharmacology
Animals
Electron
Evoked Potentials/drug effects
Grover L M
Hippocampus/*physiology
In Vitro Techniques
Microscopy
N-Methyl-D-Aspartate/*physiology
N-Methylaspartate/*pharmacology
Neuroscience
Pyramidal Tracts/drug effects/*physiology
Rats
Receptors
Teyler T J
Time Factors
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1038/347477a0" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/347477a0</a>
Pages
477–479
Issue
6292
Volume
347
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Two components of long-term potentiation induced by different patterns of afferent activation.
Publisher
An entity responsible for making the resource available
Nature
Date
A point or period of time associated with an event in the lifecycle of the resource
1990
1990-10
Subject
The topic of the resource
2-Amino-5-phosphonovalerate/*pharmacology; Afferent Pathways/physiology; Animals; Calcium/*physiology; Hippocampus/*physiology; In Vitro Techniques; Membrane Potentials; Memory/*physiology; N-Methyl-D-Aspartate/*physiology; Neuronal Plasticity; Receptors; Synaptic Transmission; Time Factors
Creator
An entity primarily responsible for making the resource
Grover L M; Teyler T J
Description
An account of the resource
Long-term potentiation (LTP) of excitatory synaptic transmission could be a mechanism underlying memory. Induction of LTP requires Ca2+ influx into postsynaptic neurons through ion channels gated by NMDA (N-methyl-D-aspartate) receptors in hippocampus (area CA1 and dentate gyrus) and neocortex. Here we report that a component of LTP not requiring the activation of NMDA receptors can be induced in area CA1. The component is dependent on tetanus frequency, requires increases in postsynaptic intracellular Ca2+ concentrations, and is suppressed by an antagonist of voltage-dependent Ca2+ channels.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1038/347477a0" target="_blank" rel="noreferrer noopener">10.1038/347477a0</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1990
2-Amino-5-phosphonovalerate/*pharmacology
Afferent Pathways/physiology
Animals
Calcium/*physiology
Grover L M
Hippocampus/*physiology
In Vitro Techniques
Membrane Potentials
Memory/*physiology
N-Methyl-D-Aspartate/*physiology
Nature
Neuronal Plasticity
Receptors
Synaptic Transmission
Teyler T J
Time Factors
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1523/JNEUROSCI.2894-06.2007" target="_blank" rel="noreferrer noopener">http://doi.org/10.1523/JNEUROSCI.2894-06.2007</a>
Pages
1954–1963
Issue
8
Volume
27
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Contribution of NMDA and AMPA receptors to temporal patterning of auditory responses in the inferior colliculus.
Publisher
An entity responsible for making the resource available
The Journal of neuroscience : the official journal of the Society for Neuroscience
Date
A point or period of time associated with an event in the lifecycle of the resource
2007
2007-02
Subject
The topic of the resource
Animals; Chiroptera/*physiology; Neurons/physiology; Action Potentials/drug effects; Excitatory Amino Acid Antagonists/pharmacology; Quinoxalines/pharmacology; Inferior Colliculi/cytology/drug effects/*physiology; Piperazines/pharmacology; *Acoustic Stimulation; Reaction Time/drug effects/*physiology; N-Methyl-D-Aspartate/*physiology; Receptors; AMPA/*physiology
Creator
An entity primarily responsible for making the resource
Sanchez Jason Tait; Gans Donald; Wenstrup Jeffrey J
Description
An account of the resource
Although NMDA receptors (NMDARs) are associated with synaptic plasticity, they form an essential part of responses to sensory stimuli. We compared contributions of glutamatergic NMDARs and AMPA receptors (AMPARs) to auditory responses in the inferior colliculus (IC) of awake, adult mustached bats. We examined the magnitude and temporal pattern of responses to tonal signals in single units before, during, and after local micro-iontophoretic application of selective antagonists to AMPARs [NBQX (1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide)] and NMDARs [CPP ((+/-)3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid)]. Combined blockade of AMPARs and NMDARs eliminated excitatory responses in nearly all neurons, whereas separate blockade of each receptor was quantitatively similar, causing substantial (\textgreater 50%) spike reductions in approximately 75% of units. The major result was that effects of receptor blockade were most closely related to the first-spike latency of a unit. Thus, AMPAR blockade substantially reduced spikes in all short-latency units (\textless 12 ms) but never in long-latency units (\textgreater or = 12 ms). NMDAR blockade had variable effects on short-latency units but reduced spikes substantially for all long-latency units. There were no distinct contributions of AMPARs and NMDARs to early and late elements of responses. Thus, AMPAR blockade reduced early (onset) spikes somewhat more effectively than NMDAR blockade in short-latency units, but NMDAR blockade reduced onset spikes more effectively in long-latency units. AMPAR and NMDAR blockade were equally effective in reducing later elements of sustained responses in short-latency units, whereas NMDAR blockade was much more effective in long-latency units. These results indicate that NMDARs play multiple roles for signal processing in adult IC neurons.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1523/JNEUROSCI.2894-06.2007" target="_blank" rel="noreferrer noopener">10.1523/JNEUROSCI.2894-06.2007</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Acoustic Stimulation
2007
Action Potentials/drug effects
AMPA/*physiology
Animals
Chiroptera/*physiology
College of Anatomy & Neurobiology
Department of Anatomy & Neurobiology
Excitatory Amino Acid Antagonists/pharmacology
Gans Donald
Inferior Colliculi/cytology/drug effects/*physiology
N-Methyl-D-Aspartate/*physiology
NEOMED College of Medicine
Neurons/physiology
Piperazines/pharmacology
Quinoxalines/pharmacology
Reaction Time/drug effects/*physiology
Receptors
Sanchez Jason Tait
The Journal of neuroscience : the official journal of the Society for Neuroscience
Wenstrup Jeffrey J