Browse Items · NEOMED Bibliography Database

Psychiatric Diagnostic Uncertainty: Challenges to Patient-Centered Care.

In this case and commentary, a patient's request to be treated for depression without a stigmatizing diagnostic label of bipolar II disorder challenges a clinician's obligation to provide a clinically and ethically appropriate diagnosis and safe…

Uncovering the hidden medical curriculum through a pedagogy of discomfort.

What lies beneath the formal or overt curriculum may impair students' professional growth and development, including their ability to foster genuine relationships with patients and others, and may contribute to the inadvertent, often negative…

Tags: *Curriculum, *Decision Making, *Physician-Patient Relations, 2005, Adult, Advances in health sciences education : theory and practice, Aultman Julie M, College of Graduate Studies, Department of Family & Community Medicine, Education, Female, Humans, Medical, Models, NEOMED College of Graduate Studies, NEOMED College of Medicine, Psychological, Undergraduate/*methods

Crisis Intervention Team (CIT) programs in rural communities: a focus group study.

The Crisis Intervention Teams model (CIT) was originally developed as an urban model for police officers responding to calls about persons experiencing a mental illness crisis. Literature suggests that there is reason to believe that there may be…

Disease Burden Among Individuals with Severe Mental Illness in a Community Setting.

This study examines the prevalence of comorbid physical health conditions within a community sample of individuals with severe mental illness (SMI), compares them to a matched national sample without SMI, and identifies which comorbidities create the…

The diseased embodied mind: constructing a conception of mental disease in relation to the person.

Without a better understanding of mental disease, patients diagnosed with a mental disease may be mistreated clinically and/or socially, and caregivers and families may be wrongfully blamed for causing the disease and/or for not effectively helping…

Don't let the bedbugs bite: the Cimicidae debacle and the denial of healthcare and social justice.

Although bedbug infestation is not a new public health problem, it is one that is becoming more alarming among healthcare professionals, public health officials, and ethicists given the magnitude of patients who may be denied treatment, or who are…

Engineering triiodothyronine (T3) nanoparticle for use in ischemic brain stroke.

A potential means of pharmacological management of ischemic stroke is rapid intervention using potent neuroprotective agents. Thyroid hormone (T3) has been shown to protect against ischemic damage in middle cerebral artery occlusion (MCAO) model of…

Tags: 2013, Blood-brain barrier, Brain stroke, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug delivery and translational research, Geldenhuys Werner J, Mdzinarishvili Alexander, Nanoparticles, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Neuroprotection, Sadana Prabodh, Sutariya Vijaykumar, Talasila Phani K, Thyroid hormone

Identification of a novel serum and glucocorticoid regulated kinase-1 (SGK1) ligand from virtual screening.

The serum and glucocorticoid regulated kinase-1 (SGK1) is part of the serine/threonine kinase family and has therapeutic potential in several neurodegenerative diseases such as ischemic stroke and Parkinson's disease. Here we use structure-based…

Tags: 2012, Binding Sites, Bioorganic & medicinal chemistry letters, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug Discovery, Geldenhuys Werner J, Humans, Immediate-Early Proteins/*antagonists & inhibitors/chemistry/metabolism, Ligands, Molecular Docking Simulation, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Protein Kinase Inhibitors/*chemistry/*pharmacology, Protein-Serine-Threonine Kinases/*antagonists & inhibitors/chemistry/metabolism, Sadana Prabodh, Talasila Phani K

A novel Lipoprotein lipase (LPL) agonist rescues the enzyme from inhibition by angiopoietin-like 4 (ANGPTL4).

Lipoprotein lipase (LPL) is a key physiological regulator of triglycerides and atherosclerosis risk. Random screening identified a compound designated C10, showing greater LPL agonist activity than NO-1886, a known LPL agonist. Structure-activity…

Structure-activity and in vivo evaluation of a novel lipoprotein lipase (LPL) activator.

Elevated triglycerides (TG) contribute towards increased risk for cardiovascular disease. Lipoprotein lipase (LPL) is an enzyme that is responsible for the metabolism of core triglycerides of very-low density lipoproteins (VLDL) and chylomicrons in…

Novel compounds that target lipoprotein lipase and mediate growth arrest in acute lymphoblastic leukemia.

Over the past decade, the therapeutic strategies employed to treat B-precursor acute lymphoblastic leukemia (ALL) have been progressively successful in treating the disease. Unfortunately, the treatment associated dyslipidemia, either acute or…

Tags: *Acute lymphoblastic leukemia, *Cancer, *Co-culture model, *Lipids, *Lipoprotein lipase, *Metabolism, 2018, Amides/chemistry/metabolism/pharmacology, Antineoplastic Agents/*chemistry/metabolism/pharmacology, Binding Sites, Bioorganic & medicinal chemistry letters, Cell Line, Cell Proliferation/drug effects, Coculture Techniques, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dyslipidemias/complications/metabolism/pathology, Geldenhuys Werner J, Gibson Laura F, Humans, Lipoprotein Lipase/antagonists & inhibitors/*metabolism, Mesenchymal Stem Cells/cytology/metabolism, Molecular Docking Simulation, Nair Rajesh R, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Piktel Debbie, Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications/metabolism/pathology, Protein Binding, Protein Structure, Sadana Prabodh, Serum Albumin/chemistry/metabolism, Tertiary, Tumor

Perceptions of child protective services among pregnant or recently pregnant, opioid-using women in substance abuse treatment.

Pregnant, opioid-using women represent a challenge to healthcare providers attempting to engage them in prenatal and substance abuse services. Limited, primarily international research suggests that child welfare clients have mixed feelings about…

Tags: 2018, Aultman Julie, Barriers to substance abuse treatment, Child abuse & neglect, Child protective services, College of Graduate Studies, College of Medicine, Department of Family & Community Medicine, Falletta Lynn, Fischbein Rebecca, Hamilton Kelsey, Kenne Deric, Kinney Beth, NEOMED College of Graduate Studies, NEOMED College of Medicine, Opioid dependence, Pregnancy

Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases.

Although statins and other pharmacological approaches have improved the management of lipid abnormalities, there exists a need for newer treatment modalities especially for the management of hypertriglyceridemia. Lipoprotein lipase (LPL), by…

Tags: 2017, Animals, Cardiovascular Diseases/drug therapy/*enzymology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug Discovery Today, Geldenhuys Werner J, Humans, Lin Li, Lipoprotein Lipase/chemistry/*metabolism, Metabolic Diseases/drug therapy/*enzymology, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana Prabodh

Crisis intervention team officer dispatch, assessment, and disposition: Interactions with individuals with severe mental illness.

The Crisis Intervention Team (CIT) model is a specialized police response program for people in a mental illness crisis. We analyzed 2174 CIT officers' reports from one community, which were completed during a five year period. These officers'…

Police officer perceptions of the impact of Crisis Intervention Team (CIT) programs.

The Crisis Intervention Team (CIT) program is an approach for law enforcement officers to safely response to individuals who are experiencing a mental health crisis. Research must identify the components of CIT that are instrumental to the overall…

Exploring the relationship between criminogenic risk assessment and mental health court program completion.

The two primary goals of mental health courts are to engage individuals with severe mental illness in the criminal justice system with clinical mental health services and to prevent future involvement with the criminal justice system. An important…

Tags: *Needs Assessment, *Risk Assessment, 2016, Bonfine Natalie, Clinical services, College of Graduate Studies, Comparative Studies, Criminal Law/*legislation & jurisprudence, Criminals/*legislation & jurisprudence/*psychology, Criminogenic risk assessment, Criminology – Legislation and Jurisprudence, Department of Family & Community Medicine, Department of Psychiatry, Evaluation Research, Goals, Goals and Objectives, Human, Humans, International journal of law and psychiatry, Judicial Role, Jurisprudence, Mental Disorders – Therapy, Mental Disorders/*therapy, Mental health court, Mental Health Services, Mentally Ill Persons/*legislation & jurisprudence/*psychology, Multicenter Studies, Munetz Mark R, Needs Assessment, NEOMED College of Graduate Studies, NEOMED College of Medicine, Ohio, Psychiatric Patients – Legislation and Jurisprudence, Psychiatric Patients – Psychosocial Factors, Public Offenders – Legislation and Jurisprudence, Public Offenders – Psychosocial Factors, Risk Assessment, Ritter Christian, Scales, Validation Studies

Anti-edema action of thyroid hormone in MCAO model of ischemic brain stroke: Possible association with AQP4 modulation.

The use of neuroprotective strategies to mitigate the fatal consequences of ischemic brain stroke is a focus of robust research activity. We have previously demonstrated that thyroid hormone (T3; 3,3',5-triiodo-l-thyronine) possesses neuroprotective…

Effects of vascular endothelial growth factor on wound closure rates in the genetically diabetic mouse model.

Impaired wound healing is characteristic of diabetic patients. Potential reasons include poor inflammatory response, granulation tissue formation, and abnormal patterns of cytokine release and response. Vascular endothelial growth factor, abnormally…

Managing in the trenches of consumer care: the challenges of understanding and initiating the advance care planning process.

To better understand how community-based long-term care providers define advance care planning and their role in the process, we conducted 8 focus groups with 62 care managers (social workers and registered nurses) providing care for Ohio's Medicaid…

Tags: *Health Personnel/psychology/standards, *Health Services for the Aged, *Long-Term Care/methods/organization & administration/psychology, *Patient Care Management/methods/organization & administration, 2012, advance care planning, Advance Care Planning/*organization & administration, Attitude of Health Personnel, Aultman Julie, Baughman Kristin R, Case Management, College of Graduate Studies, Convenience Sample, Decision Making, Department of Family & Community Medicine, Family Relations, Focus Groups, Funding Source, Hazelett Susan, Human, Humans, Interpersonal Relations, Journal of gerontological social work, Long Term Care, Ludwick Ruth, Needs Assessment, NEOMED College of Graduate Studies, NEOMED College of Medicine, Nurse Attitudes, O'Neill Anne, Ohio, Palmisano Barbara, Patient Education as Topic, Professional Role, Professional-Patient Relations, Qualitative Research, Qualitative Studies, Sanders Margaret, Social Work/*standards, Social Worker Attitudes, Terminal Care/organization & administration/psychology, Thematic Analysis

Retheorizing sexual harassment in medical education: women students' perceptions at five U.S. medical schools.

BACKGROUND: The literature consistently reports that sexual harassment occurs with regularity in medical education, mostly in clinical settings, and most of it goes unreported. Reasons for nonreporting include the fear of retaliation, a reluctance to…

A foreigner in my own country: forgetting the heterogeneity of our national community.

Tags: *Bioethics, *Poverty, *Social Welfare, 2006, Aultman Julie M, Awareness, College of Graduate Studies, Department of Family & Community Medicine, Empirical Research, Employment, Humans, Information Dissemination, NEOMED College of Graduate Studies, NEOMED College of Medicine, Rural Health Services/*ethics, The American journal of bioethics : AJOB, United States

Moral courage through a collective voice.

Conceptualizing disease: unifying the divide between philosophical inquiry and empirical research.

Creating moral conflict through an inequality sensitive summary measure.

Dissolution of ESCROs and evolution of a national ethics committee for scientific advancement.

Tags: *Policy Making, *Public Policy, *Stem Cell Research, 2013, Aultman Julie, College of Graduate Studies, Department of Family & Community Medicine, Embryo Research – Ethical Issues, Ethics Committees, Government Regulations – United States, Humans, Institutional Review, NEOMED College of Graduate Studies, NEOMED College of Medicine, Stem Cell Research – Ethical Issues, The American journal of bioethics : AJOB, United States

Building global inter-IRB trust: A cultural immersion challenge.

Tags: *Biomedical Research, *Ethics Committees, *Human Experimentation, *International Cooperation, 2014, Aultman Julie, collaboration, College of Graduate Studies, Cultural Diversity, Culture, Department of Family & Community Medicine, Humans, Institutional Review, NEOMED College of Graduate Studies, NEOMED College of Medicine, Research, The American journal of bioethics : AJOB

Vulnerability: its meaning and value in the context of contemporary bioethics.

When saying sorry is not enough: acknowledging past wrongs in human subjects research.

Ethics of translation: MOLST and electronic advance directives.

Tags: *Advance Directives/ethics, *Decision Making, *Electronics, *Life Support Care/ethics, *Resuscitation Orders, *Terminal Care/ethics, 2010, Advance Care Planning – Ethical Issues, Advance Directives – Ethical Issues, Aultman Julie M, Cardiopulmonary, Cardiopulmonary Resuscitation/ethics, College of Graduate Studies, Communication, Computer Assisted, Computer-Assisted, Decision Making, Decision Making/ethics, Decision Support Techniques, Department of Family & Community Medicine, Humans, Life Support Care – Ethical Issues, Medical, Medical Orders, NEOMED College of Graduate Studies, NEOMED College of Medicine, Patient, Patient Autonomy, Personal Values, Resuscitation, Resuscitation Orders, Right to Die, Terminal Care – Ethical Issues, The American journal of bioethics : AJOB, United States, Values Clarification

Making fun of patients: medical students' perceptions and use of derogatory and cynical humor in clinical settings.

PURPOSE: It has long been known that medical students become more cynical as they move through their training, and at times even exhibit "ethical erosion." This study examines one dimension of this phenomenon: how medical students perceive and use…

Remembering Freddie Gray: Medical Education for Social Justice.

Recent attention to racial disparities in law enforcement, highlighted by the death of Freddie Gray, raises questions about whether medical education adequately prepares physicians to care for persons particularly affected by societal inequities and…

Evolution of the Academic Health Department through public health academic and practice collaborations.

In 1997, the Office of Public Health Practice was chartered at Northeast Ohio Medical University (NEOMED). Through this office, public health practitioners and academics have engaged in informal collaborations, formal collaborations, and formal…

Derogatory and cynical humour directed towards patients: views of residents and attending doctors.

CONTEXT: A study of medical students' perspectives on derogatory and cynical humour was published in 2006. The current study examines residents' and attending doctors' perspectives on the same phenomenon in three clinical departments of psychiatry,…

A genethics debate within an interdisciplinary curriculum.

The limits of narrative: medical student resistance to confronting inequality and oppression in literature and beyond.

INTRODUCTION: Upon designing and implementing a literature course on family values for Year 4 medical students, we found that while the supposed benefits of literary inquiry were to lead students to a deeper understanding of difficult issues such as…

A broader understanding of care managers' attitudes of advance care planning: A concurrent nested design.

AIMS AND OBJECTIVES: To examine barriers of advance care planning (ACP) experienced by care managers (CMs) through a mixed methods approach. A concurrent nested design was used to acquire a deeper understanding of ACP and to identify nuances between…

Tags: *Attitude of Health Personnel, *Health Knowledge, 2018, Adult, advance care planning, Advance Care Planning/*standards, Attitudes, Aultman Julie, Baughman Kristin R, Case Managers, Chi Square Test, College of Graduate Studies, Community health, Concurrent Prospective Studies, Convenience Sample, Decision-making, Department of Family & Community Medicine, Discussion, end of life, Female, Focus Groups, Funding Source, Health Services Accessibility/standards, Human, Humans, Journal of clinical nursing, Ludwick Ruth, Male, Middle Age, Middle Aged, Midwestern United States, Multicenter Studies, Multimethod Studies, NEOMED College of Graduate Studies, NEOMED College of Medicine, Nurse Attitudes, nurses, Practice, Qualitative, Qualitative Research, quantitative, Questionnaires, Surveys, Surveys and Questionnaires, Thematic Analysis

A Comparison of Participants in Two Community-Based Programs: Assisted Outpatient Treatment and a Mental Health Court.

OBJECTIVE: Mental health courts and assisted outpatient treatment (AOT) are tools to help people with serious mental illness engage in treatment and avoid or reduce institutionalization. As both programs become increasingly prevalent, questions…

Tags: 2018, Assisted Outpatient Treatment, Bonfine Natalie, College of Graduate Studies, Department of Family & Community Medicine, Department of Psychiatry, mental health courts, Munetz Mark R, NEOMED College of Graduate Studies, NEOMED College of Medicine, Outpatient commitment, Psychiatric services (Washington, D.C.), Ritter Christian, Teller Jennifer L S

Crime, Vulnerability, and AOT.

Tags: *Crime, *Mental Health Services, 2017, Aultman Julie M, College of Graduate Studies, Department of Family & Community Medicine, Department of Psychiatry, Humans, Munetz Mark R, NEOMED College of Graduate Studies, NEOMED College of Medicine, Outpatients, Psychiatric services (Washington, D.C.), Research

An examination of premature mortality among decedents with serious mental illness and those in the general population.

OBJECTIVES: The primary aim of this retrospective study of death records was to determine whether there were significant differences in years of potential life lost (YPLL) between decedents with serious and persistent mental illness at a community…

Narrative analysis of the ethics in providing advance care planning.

Our objective was to better understand the values and ethical dilemmas surrounding advance care planning through stories told by registered nurses and licensed social workers, who were employed as care managers within Area Agencies on Aging. We…

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