1 40 2 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1002/lary.24813" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/lary.24813</a> Pages 70–74 Issue 1 Volume 125 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Pathophysiology of empty nose syndrome. Publisher An entity responsible for making the resource available The Laryngoscope Date A point or period of time associated with an event in the lifecycle of the resource 2015 2015-01 Subject The topic of the resource Brain – Physiopathology; Brain/physiopathology; Computer Simulation; Dyspnea – Physiopathology; Dyspnea/physiopathology; Empty nose syndrome; Humans; Nasal Mucosa – Innervation; Nasal Mucosa/*innervation; Nasal Obstruction – Physiopathology; Nasal Obstruction/*physiopathology; nasal sensation; Neural Pathways – Physiopathology; Olfactory Pathways/physiopathology; Postoperative Complications – Physiopathology; Postoperative Complications/*physiopathology; Pulmonary Ventilation/*physiology; Respiratory Airflow – Physiology; Sensory Receptor Cells – Physiology; Sensory Receptor Cells/*physiology; Syndrome; Thermoreceptors – Physiopathology; Thermoreceptors/physiopathology; Tomography; Trigeminal Nerve – Physiopathology; Trigeminal Nerve/physiopathology; turbinate surgery; Turbinates – Physiopathology; Turbinates – Surgery; Turbinates/*physiopathology/*surgery; Wound Healing – Physiology; Wound Healing/*physiology; X-Ray Computed Creator An entity primarily responsible for making the resource Sozansky Jeanie; Houser Steven M Description An account of the resource OBJECTIVES/HYPOTHESIS: To review current knowledge on nasal airflow sensation in relation to empty nose syndrome (ENS). STUDY DESIGN: PubMed searches. METHODS: Current literature pertaining to measurement of nasal patency, mechanism of sensory perception of nasal airflow, and ENS. RESULTS: A reliance on pure anatomical analysis of the anatomy in ENS falls short of explaining the disorder. Our understanding of subjective nasal sensation has advanced, as has our understanding of the flow of air through the nose. Neural healing following a surgical insult may not result in a return to a normal physiologic state. Aberrations in neurosensory systems from improper healing may play a major role in the abnormal sensations ENS patients experience. CONCLUSIONS: An evidence-based hypothesis for the development and symptoms of ENS is offered. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1002/lary.24813" target="_blank" rel="noreferrer noopener">10.1002/lary.24813</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). 2015 Brain – Physiopathology Brain/physiopathology Computer Simulation Dyspnea – Physiopathology Dyspnea/physiopathology Empty nose syndrome Houser Steven M Humans Nasal Mucosa – Innervation Nasal Mucosa/*innervation Nasal Obstruction – Physiopathology Nasal Obstruction/*physiopathology nasal sensation Neural Pathways – Physiopathology Olfactory Pathways/physiopathology Postoperative Complications – Physiopathology Postoperative Complications/*physiopathology Pulmonary Ventilation/*physiology Respiratory Airflow – Physiology Sensory Receptor Cells – Physiology Sensory Receptor Cells/*physiology Sozansky Jeanie Syndrome The Laryngoscope Thermoreceptors – Physiopathology Thermoreceptors/physiopathology Tomography Trigeminal Nerve – Physiopathology Trigeminal Nerve/physiopathology turbinate surgery Turbinates – Physiopathology Turbinates – Surgery Turbinates/*physiopathology/*surgery Wound Healing – Physiology Wound Healing/*physiology X-Ray Computed Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1002/alr.21368" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/alr.21368</a> Pages 834–838 Issue 10 Volume 4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The physiological mechanism for sensing nasal airflow: a literature review. Publisher An entity responsible for making the resource available International forum of allergy & rhinology Date A point or period of time associated with an event in the lifecycle of the resource 2014 2014-10 Subject The topic of the resource Body Temperature Regulation/physiology; computational fluid dynamics modeling; Computer Simulation; Humans; mucosal cooling; nasal airflow sensation; Nasal Cavity/*physiology; nasal congestion; Nasal Mucosa/*physiology; Nasal Obstruction/*physiopathology; Pulmonary Ventilation/physiology; TRPM8 Creator An entity primarily responsible for making the resource Sozansky Jeanie; Houser Steven M Description An account of the resource BACKGROUND: Nasal obstruction is a common otolaryngologic complaint, yet the mechanism of sensing airflow is not commonly understood. The objective of this work was to review current knowledge on the physiological mechanism for sensing nasal airflow. METHODS: Current literature pertaining to nasal sensation to airflow was retrieved using PubMed and Google Scholar searches. RESULTS: The primary physiological mechanism that produces the sensation of ample nasal airflow is activation of trigeminal cool thermoreceptors, specifically transient receptor potential melastatin family member 8 (TRPM8), by nasal mucosal cooling. The dynamic change in temperature is ultimately sensed. Nasal mucosal cooling is a result of conductive heat loss, driven by temperature gradient, and evaporative heat loss, driven by humidity gradient. The perception of ample nasal airflow is dependent on the overall nasal surface area stimulated by mucosal cooling, which is mainly governed by air flow patterns. Cool thermoreceptors in the nasal mucosa are connected to the respiratory centers and consequently can alter respiration patterns. Mechanoreceptors do not seem to play a role in sensing nasal airflow. Computational fluid dynamics (CFD) modeling could be a valuable objective tool in evaluating patients with nasal congestion. CONCLUSION: Understanding the physiological mechanism of how the nose senses airflow can aid in diagnosing the cause behind patient symptoms, which allows physicians to provide better treatment options for patients. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1002/alr.21368" target="_blank" rel="noreferrer noopener">10.1002/alr.21368</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). 2014 Body Temperature Regulation/physiology computational fluid dynamics modeling Computer Simulation Houser Steven M Humans International forum of allergy & rhinology mucosal cooling nasal airflow sensation Nasal Cavity/*physiology nasal congestion Nasal Mucosa/*physiology Nasal Obstruction/*physiopathology Pulmonary Ventilation/physiology Sozansky Jeanie TRPM8