Browse Items · NEOMED Bibliography Database

Interplay between low threshold voltage-gated K(+) channels and synaptic inhibition in neurons of the chicken nucleus laminaris along its frequency axis.

Central auditory neurons that localize sound in horizontal space have specialized intrinsic and synaptic cellular mechanisms to tightly control the threshold and timing for action potential generation. However, the critical interplay between…

Ambient GABA-activated tonic inhibition sharpens auditory coincidence detection via a depolarizing shunting mechanism.

Tonic inhibition mediated by extrasynaptic GABA(A) receptors (GABA(A)Rs) has emerged as a novel form of neural inhibition in the CNS. However, little is known about its presence and function in the auditory system. Using whole-cell recordings in…

Inputs to combination-sensitive neurons in the medial geniculate body of the mustached bat: the missing fundamental.

This study examined projections to combination-sensitive neurons in the medial geniculate body of the mustached bat. These specialized neurons respond to the combination of two temporally and spectrally distinct components of the bat's sonar pulse…

Temporal features of spectral integration in the inferior colliculus: effects of stimulus duration and rise time.

This report examines temporal features of facilitation and suppression that underlie spectrally integrative responses to complex vocal signals. Auditory responses were recorded from 160 neurons in the inferior colliculus (IC) of awake mustached bats.…

Frequency organization and responses to complex sounds in the medial geniculate body of the mustached bat.

The auditory cortex of the mustached bat (Pteronotus parnellii) displays some of the most highly developed physiological and organizational features described in mammalian auditory cortex. This study examines response properties and organization in…

Tags: *Brain Mapping, 1999, Animal, Animals, Auditory Cortex/*physiology, Auditory Perception/*physiology, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Electrophysiology/methods, Geniculate Bodies/*physiology, Journal of neurophysiology, NEOMED College of Medicine, Neurons/*physiology, Pitch Discrimination/*physiology, Reaction Time, Ultrasonics, Vocalization, Wenstrup J J

Delay-tuned neurons in the inferior colliculus of the mustached bat: implications for analyses of target distance.

We examined response properties of delay-tuned neurons in the central nucleus of the inferior colliculus (ICC) of the mustached bat. In the mustached bat, delay-tuned neurons respond best to the combination of the first-harmonic, frequency-modulated…

Tags: 1999, Animal/physiology, Animals, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Echolocation/*physiology, Inferior Colliculi/cytology/*physiology, Journal of neurophysiology, NEOMED College of Medicine, Neural Inhibition/physiology, Neurons/*physiology, Portfors C V, Reaction Time/physiology, Vocalization, Wenstrup J J

Intracellular recording reveals temporal integration in inferior colliculus neurons of awake bats.

The central nucleus of the inferior colliculus (IC) is a major integrative center in the central auditory system. It receives information from both the ascending and descending auditory pathways. To determine how single IC neurons integrate…

Tags: 2007, Acoustic Stimulation, Animals, Chiroptera/*physiology, Data Interpretation, Department of Anatomy & Neurobiology, Electrophysiology, Excitatory Postsynaptic Potentials/physiology, Galazyuk A V, Inferior Colliculi/cytology/*physiology, Inhibitory Postsynaptic Potentials/physiology, Journal of neurophysiology, Microelectrodes, NEOMED College of Medicine, Neurons/*physiology, Pitch Perception, Statistical, Voytenko S V

Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons.

GABAergic transmission in the avian cochlear nucleus magnocellularis (NM) of the chick is subject to modulation by gamma-aminobutyric acid type B (GABA(B)) autoreceptors. Here, I investigated modulation of GABAergic transmission in NM by metabotropic…

Tags: 2-Amino-5-phosphonovalerate/pharmacology, 2007, Amino Acids/pharmacology, Animals, Chickens/*physiology, Cochlear Nucleus/*cytology/*physiology, Department of Anatomy & Neurobiology, Electric Stimulation, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/physiology, GABA-B Receptor Agonists, GABA-B Receptor Antagonists, GABA-B/physiology, gamma-Aminobutyric Acid/*physiology, Glycine/analogs & derivatives/pharmacology, In Vitro Techniques, Journal of neurophysiology, Kinetics, Lu Yong, Membrane Potentials/drug effects, Metabotropic Glutamate/agonists/antagonists & inhibitors/*metabolism/physiology, Models, NEOMED College of Medicine, Neurological, Neurons/*physiology, Patch-Clamp Techniques, Receptors, Resorcinols/pharmacology, Synapses/physiology, Synaptic Transmission/*physiology, Xanthenes/pharmacology

L-type calcium channels refine the neural population code of sound level.

The coding of sound level by ensembles of neurons improves the accuracy with which listeners identify how loud a sound is. In the auditory system, the rate at which neurons fire in response to changes in sound level is shaped by local networks.…

A novel coding mechanism for social vocalizations in the lateral amygdala.

The amygdala plays a central role in evaluating the significance of acoustic signals and coordinating the appropriate behavioral responses. To understand how amygdalar responses modulate auditory processing and drive emotional expression, we assessed…

Control of a depolarizing GABAergic input in an auditory coincidence detection circuit.

Neurons in the chicken nucleus laminaris (NL), the third-order auditory neurons that detect the interaural time differences that enable animals to localize sounds in the horizontal plane, receive glutamatergic excitation from the cochlear nucleus…

Central visual pathways in glaucoma: evidence for distal mechanisms of neuronal self-repair.

As in other age-related neurodegenerative diseases, progression of neurodegeneration in glaucoma involves early axonopathy. In glaucoma, this is marked by degradation of active transport along retinal ganglion cell (RGC) axons projecting from the…

Tags: 2015, Calkins David J, Crish Samuel D, Department of Pharmaceutical Sciences, Glaucoma/*pathology/*physiopathology, Humans, Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, NEOMED College of Pharmacy, Neurons/*physiology, Recovery of Function/*physiology, Visual Pathways/*physiopathology

Selectivity and persistent firing responses to social vocalizations in the basolateral amygdala.

This study examined responsiveness to acoustic stimuli among neurons of the basolateral amygdala. While recording from single neurons in awake mustached bats (Pteronotus parnellii), we presented a wide range of acoustic stimuli including tonal,…

Tags: 2012, Acoustic Stimulation, Action Potentials/*physiology, Amygdala/*physiology, Animal/*physiology, Animals, Auditory/physiology, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Echolocation/physiology, Evoked Potentials, NEOMED College of Medicine, Neurons/*physiology, Neuroscience, Peterson D C, Vocalization, Wenstrup J J

Timing of sound-evoked potentials and spike responses in the inferior colliculus of awake bats.

Neurons in the inferior colliculus (IC), one of the major integrative centers of the auditory system, process acoustic information converging from almost all nuclei of the auditory brain stem. During this integration, excitatory and inhibitory inputs…

Inputs to combination-sensitive neurons of the inferior colliculus.

In the mustached bat, combination-sensitive neurons display integrative responses to combinations of acoustic elements in biosonar or social vocalizations. One type of combination-sensitive neuron responds to multiple harmonics of the…

Tags: *Brain Mapping, 1999, Acoustic Stimulation, Animals, Auditory, Brain Stem/*physiology, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Evoked Potentials, Grose C D, Inferior Colliculi/*physiology, Mittmann D H, NEOMED College of Medicine, Neurons/*physiology, The Journal of comparative neurology, Wenstrup J J

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