Browse Items (7 total)
- Tags: Neurotoxicology
Trimethyltin intoxication induces the migration of ventricular/subventricular zone cells to the injured murine hippocampus.
Tags: *Brain injury, *Hippocampus, *Neural stem cells, *Neurogenesis, *Subventricular stem cells, *Trimethyltin, 2016, Amino Acids/metabolism, Animals, Brain Injuries/*pathology, Bromodeoxyuridine/metabolism, Cell Movement/*drug effects, Department of Pharmaceutical Sciences, Functional Laterality, Glial Fibrillary Acidic Protein/metabolism, Hippocampus/*pathology, Inbred C3H, Lateral Ventricles/drug effects/*pathology, Lowndes Herbert E, Male, Mice, NEOMED College of Pharmacy, Neurogenesis/drug effects/physiology, Neurotoxicology, Reuhl Kenneth R, Richardson Jason R, Trimethyltin Compounds/*toxicity, Weig Blair C
Developmental pyrethroid exposure causes long-term decreases of neuronal sodium channel expression.
Tags: 2017, Animals, BDNF, Brain-Derived Neurotrophic Factor/metabolism, Cerebral Cortex/*drug effects/growth & development/metabolism, Corpus Striatum/*drug effects/growth & development/metabolism, Deltamethrin, Department of Pharmaceutical Sciences, Female, Inbred C57BL, Insecticides/*toxicity, Magby Jason P, Male, Messenger/metabolism, Mice, NEOMED College of Pharmacy, Neurodevelopmental, Neurons/*drug effects/metabolism, Neurotoxicology, Nitriles/*toxicity, Pregnancy, Prenatal Exposure Delayed Effects/*metabolism, Pyrethrins/*toxicity, Pyrethroid, Richardson Jason R, RNA, Sodium channel, Voltage-Gated Sodium Channels/*metabolism
MPTP neurotoxicity is highly concordant between the sexes among BXD recombinant inbred mouse strains.
Tags: *QTL, *Recombinant inbred mice, *Sex Characteristics, *Sex differences, 1-Methyl-4-phenyl-1, 2, 2016, 3, 4-Dihydroxyphenylacetic Acid/metabolism, 6-tetrahydropyridine/pharmacology, Alam Gelareh, Animal, Animals, Corpus Striatum/drug effects/*metabolism, Department of Family & Community Medicine, Disease Models, Dopamine/metabolism, Female, Gene Expression Regulation/drug effects/*genetics, Glial Fibrillary Acidic Protein/*metabolism, Homovanillic Acid/metabolism, Inbred Strains, Jones Byron C, Lu Lu, Male, Mice, Miller Diane B, MPTP Poisoning/chemically induced/*pathology, NEOMED College of Medicine, Neurotoxicology, O'Callaghan James P, Serotonin/metabolism, Species Specificity, Tyrosine 3-Monooxygenase/metabolism, Williams Robert W
Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Tags: 1-Methyl-4-phenyl-1, 2, 2017, 3, 6-tetrahydropyridine/*administration & dosage, Alam Gelareh, Animals, Burchfield Shelbie L, Catecholamines/metabolism, Cell Count, Corpus Striatum/*drug effects/metabolism, Department of Pharmaceutical Sciences, Dopamine, Dopamine transporter, Dopaminergic Neurons/*drug effects/metabolism, Edler Melissa, Inbred C57BL, Male, Mice, MPTP, MPTP Poisoning, NEOMED College of Pharmacy, Neurotoxicology, Parkinsonian Disorders/*metabolism/*pathology, Richardson Jason R, Stereology, Substantia Nigra/*drug effects/metabolism, Tyrosine 3-Monooxygenase/*metabolism, Tyrosine hydroxylase, Vesicular monoamine transporter
The effect of manganese exposure in Atp13a2-deficient mice.
Tags: *Alpha-synuclein, *Lipofuscin, *Manganese, *Mice, *Parkinson's disease, *Sensorimotor function, 2018, Aga Diana S, Department of Pharmaceutical Sciences, Ekhator Osunde R, Fleming Sheila M, Holden John G, Karkare Swagata, Lemkuhl Andrew, Linn Stephen C, Liou Benjamin, Mullin Elizabeth J, NEOMED College of Pharmacy, Neurotoxicology, Pamphile Shanta, Roth Jerome A, Santiago Nicholas A, Schultheis Patrick J, Shull Gary E, Sun Ying
The effect of manganese exposure in Atp13a2-deficient mice.
Tags: *Alpha-synuclein, *Lipofuscin, *Manganese, *Parkinson's disease, *Sensorimotor function, 2018, Adenosine Triphosphatases/genetics/*metabolism, Aga Diana S, alpha-Synuclein/metabolism, Animal, Animals, Behavior, Brain/*drug effects/*metabolism, Department of Pharmaceutical Sciences, Ekhator Osunde R, Female, Fleming Sheila M, Holden John G, Inbred C57BL, Karkare Swagata, Knockout, Lemkuhl Andrew, Linn Stephen C, Liou Benjamin, Male, Manganese/metabolism/*toxicity, Membrane Proteins/genetics/*metabolism, Mice, Motor Activity, Mullin Elizabeth J, NEOMED College of Pharmacy, Neurotoxicology, Pamphile Shanta, Roth Jerome A, Santiago Nicholas A, Schultheis Patrick J, Shull Gary E, Sun Ying
Ahr And Cyp1a2 Genotypes Both Affect Susceptibility To Motor Deficits Following Gestational And Lactational Exposure To Polychlorinated Biphenyls
Tags: 2018, Aryl hydrocarbon receptor, Cerebellum, Colter B T, Curran C P, CYP1A2, Department of Pharmaceutical Sciences, developmental exposure, dioxin-like compounds, dopamine concentrations, Fleming S M, Fowler J P, Garber H F, Harding G D, Hooven M K, Howes A A, in-utero, Infante S K, Lang A L, MacDougall M C, Motor function, NEOMED College of Pharmacy, Neurosciences & Neurology, Neurotoxicology, Nigrostriatal pathways, parkinsons-disease, pcb exposure, perinatal exposure, Pharmacology & Pharmacy, Polychlorinated biphenyls, prenatal exposure, Risk Assessment, school-age, Stegman M, Taylor K R, Toxicology