On the stability of the ripple phase in the DPPC/PLPC/water ternary system
Biophysics; Biochemistry & Molecular Biology; gel; cholesterol; lysolecithin; membranes; nuclear-magnetic-resonance; water; transition; lipid bilayers; phospholipid-bilayers; Lipids; differential scanning calorimetry (DSC); lecithin; phosphatidylcholine; phosphatidylcholine bilayers; pretransition; scanning dilatometry (SD)
The effect of incorporation of 1-palmitoyl-sn-glycero-3-phosphocholine (PLPC) on the structure of the P-beta' ripple mesophase in aqueous dispersions of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) has been studied by differential scanning calorimetry (DSC) and scanning dilatometry (SD). For samples containing 34 wt. % (H2O)-H-2 and 0-15 wt. % PLPC, a pretransition was observed by DSC. The pretransition disappears at 15 wt. % PLPC. The behavior of thermodynamic functions at the pretransition and main transition gives new insights on the structural changes produced by PLPC on bilayers of DPPC. (C) 1997 Elsevier Science Ireland Ltd.
Checchetti A; Chidichimo G; Golemme A; Grasso D; Imbardelli D; LaRosa C; Nicoletta F P; Westerman P W
Chemistry and Physics of Lipids
1997
1997-11
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/s0009-3084(97)00086-8" target="_blank" rel="noreferrer noopener">10.1016/s0009-3084(97)00086-8</a>
A thermodynamic and NMR investigation of 1-lyso-palmitoyllecithin/1,2-dipalmitoylphosphatidylethanol-amine/water system
cholesterol; Crystallography; fusion; liposomal membranes; lysolecithin; temperature; vesicle
The effect of incorporation of 1-palmitoyl-sn-glycero-3-phosphocholine (PLPC) on the bilayer structures occurring in aqueous dispersions of 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) has been studied by phosphorus 31 nuclear magnetic resonance and calorimetric methods. The polymorphism of the system as a function of PLPC concentration has been defined. Experimental data allowed us to determine phase boundaries. Changes of molecular packing of the PLPC molecules in DPPE bilayers in the phase diagram are invoked to explain the experimental findings.
Nicoletta F P; Checchetti A; Grasso D; Imbardelli D; LaRosa C; Westerman P; Chidichimo G
Molecular Crystals and Liquid Crystals Science and Technology Section a-Molecular Crystals and Liquid Crystals
1996
1996
Journal Article
<a href="http://doi.org/10.1080/10587259608031892" target="_blank" rel="noreferrer noopener">10.1080/10587259608031892</a>