Browse Items (97 total)

Aberrant liver sirtuin 1 (SIRT1), a mammalian NAD+-dependent protein deacetylase, is implicated in the pathogenesis of alcoholic liver disease. However, the role of intestinal SIRT1 in alcoholic liver disease is presently unknown. This study…

Evaluating tumor regression of rectal cancers via MRI after standard-of-care chemoradiation therapy (CRT) remains highly challenging for radiologists. While the tumor region-of-interest (ROI) on post-CRT rectal MRI is difficult to localize, an…

Macrophages play a crucial role in the pathogenesis of atherosclerosis, but the molecular mechanisms remain poorly understood. Here we show that microRNA-34a (miR-34a) is a key regulator of macrophage cholesterol efflux and reverse cholesterol…

We report the results of a 12-year retrospective study of nutritionally variant streptococcal (NVS) bacteremia in a 510-bed, a large medical school-affiliated teaching hospital. Twenty-six episodes of NVS bacteremia were identified in this…

Current surgical options for treating genu varum in achondroplasia include tibial and fibular osteotomy and growth modulation using plates and screws. However, a single surgeon consistently treated genu varum using a planned fibular nonunion (PFN).…

Psychotic disorders are not uncommon in late life. These disorders often have varied etiologies, different clinical presentations, and are associated with significant morbidity and mortality among the older adult population. Psychotic disorders in…

Pruritus is a common presenting diagnosis associated with a myriad of localized and systemic conditions. Due to many underlying causes, it can be challenging for the provider to assess. Symptoms often persist, causing frustration for the patient and…

Urban corner stores in Northeast Ohio have a reputation for contributing to neighborhood demise. Sales of liquor, cigarettes, lottery tickets, and other high-calorie low-nutrition foods along with high check-cashing fees have given corner stores…

Ugh. I am ashamed to say that is the first word that comes to my mind when I see Jake’s name on my schedule for the day. He is 10 and he has been my patient since he was born. He has an 8-year-old sister Annie and a 5-year-old brother Jimmy. They…

OBJECTIVES: To describe patient-specific characteristics associated with non-operative failure leading to surgery. PATIENTS AND METHODS: We conducted a retrospective review of patients treated for spinal metastases from 2005 to 2017. We deemed…

BACKGROUND CONTEXT: There are several prognostic scores available that intend to inform decision making for patients with spinal metastases. Many of these have not been found to reliably predict survival across the continuum of care. Recently, our…

This book describes methods of career construction counseling based on the conceptual model of life designing. It defines counseling and how career counseling has evolved over the last century. The counseling profession has evolved three distinct…

Work in the 21st century leaves people feeling anxious and insecure. Jobless work and automation have produced 'insecure workers,' especially those peripheral and external employees who perform temporary assignments. Depending upon a client's needs,…

This chapter examines the core concepts of self, identity, meaning, mastery, and mattering. It begins by discussing the role that language plays in constructing a self and then differentiates 'self' from 'identity.' The chapter explains how identity…

This chapter explains how practitioners use narrative psychology to help clients revise their career stories to increase comprehension, coherence, and continuity. Narrative therapy is an umbrella term that encompasses a variety of approaches to…

This chapter describes the framework and elements of the Career Construction Interview during which practitioners ask story-crafting questions, which scaffold career construction. The Career Construction Interview consists of stimulus questions that…

After completing a Career Construction Interview and before beginning counseling with clients, practitioners must understand the meaning presented in clients' stories, relate this meaning to the initial reason they sought counseling, and prepare to…

This chapter describes how to identify client solutions to the problems they pose in their early recollections. With a client's perspective and preoccupations in mind, practitioners begin to consider responses to the question about role models.…

This chapter discusses how to use career themes or central tensions to extend clients' occupational plots by identifying fitting settings, possible scripts, and future scenarios. Practitioners assess the educational and vocational interests that…

This chapter describes how practitioners compose an identity narrative that reconstructs clients' small stories into a large story that encourages reflexivity to clarify choices. Having conducted the eight-step assessment protocol, practitioners…

Career counseling practitioners hope that clients leave career counseling having experienced a process of transformative learning that has brought them into contact with their deepest sense of vitality. If so, clients are able to narrate a more…

OBJECTIVE: To investigate the characteristics and risk factors of a novel parenchymal lung disease (LD), increasingly detected in systemic juvenile idiopathic arthritis (sJIA). METHODS: In a multicentre retrospective study, 61 cases were investigated…

Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

The patient was a 33-year-old, highly educated, white female. She was pregnant with monochorionic-diamniotic identical twins, or twins that shared the same placenta but were in separate amniotic sacs. She had been cleared from her reproductive…

STUDY OBJECTIVE: Older adults with syncope are commonly treated in the emergency department (ED). We seek to derive a novel risk-stratification tool to predict 30-day serious cardiac outcomes. METHODS: We performed a prospective, observational study…

Context: Kratom, or Mitragyna speciosa, is a plant indigenous to Southeast Asia that has gained national attention in the United States for its increased use in the self-management of opioid withdrawal and pain, as well as for concerns about its…

INTRODUCTION: Duodenal diverticula are quite prevalent in general population, seen on up to 5% of radiology studies and up to 22% of autopsy examinations. PRESENTATION OF THE CASE: 70 years old female was admitted to the hospital with epigastric…

Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disorder characterized by arterial and venous thrombosis, often accompanied by elevated titers of anti-phospholipid antibodies. Cardiac involvement in APS is not uncommon. However,…
Output Formats

atom, dcmes-xml, json, omeka-xml, rss2