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I first met Carmendita as she was graduating from high school and needed her physical to go to college. Carmen, a bright, African American female, was so excited to be going to Muskingum University. The first person in her family to go to college,…

Tags: 2019, Department of Family & Community Medicine, Education, Health Disparities : Weaving A New Understanding Through Case Narratives, Health Policy, Health Psychology, Insurance, Janice M Spalding, Journal Article, Medical Sociology, Medicine, Medicine & Public Health, NEOMED College of Medicine, November 2019 Update, Premedical Education, Race and ethnicity, Social Work

How Can We Care for Everyone?

When I first met Charlotte, she was a 15-year-old African American boy named John. I was a white physician working at a community health center in one of the poorest zip codes in Cleveland. John and her mother came in for a well-child exam to get…

Tags: 2019, Christina Antenucci, Community, Department of Family & Community Medicine, Health Disparities : Weaving A New Understanding Through Case Narratives, Health Psychology, Journal Article, LGBT, Medical Sociology, Medicine, Medicine & Public Health, MetroHealth Medical Center, NEOMED College of Medicine, November 2019 Update, Premedical Education, Social Work, Support system, Transgender

How Clinicians Discuss Medications During Primary Care Encounters Among Older Adults with Cognitive Impairment

BACKGROUND: People with cognitive impairment experience high rates of polypharmacy and potentially inappropriate medication use. How clinicians communicate about medications may affect to what extent patients and family companions understand and…

Tags: 2019, Boyd Cynthia M, Chapman Malcolm, dementia, Echavarria Diane M, Green Ariel R, Journal Article, Journal of general internal medicine, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Phung Annie, primary care, shared decision-making, Smith Devon, Wolff Jennifer L

I Hurt Everywhere

Dr. S: Diffuse pain, possible drug-seeking behavior. Ms. K: Doc, I hurt everywhere. I’ve had all kinds of tests and no one can figure out what’s wrong with me. I went to the ER again last week because my chest was hurting and I was afraid it was my…

Tags: 2019, Chronic pain, David Sperling, Department of Family & Community Medicine, Health Disparities : Weaving A New Understanding Through Case Narratives, HEALTH literacy, Health Psychology, Journal Article, Medical Sociology, Medicine, Medicine & Public Health, NEOMED College of Medicine, November 2019 Update, Patient communication, Premedical Education, Social Work

I'm Going to Be OK

“It’s about time you got in here.” I was just a few minutes late getting started for Kathleen’s appointment, so it seemed apparent she was in a hurry. Kathleen sat in a chair next to our examination table. She was restless and her excess body weight…

Tags: 2019, Aultman Hospital, Communication, Department of Family & Community Medicine, Diabetes, Emergency, Emily Godlewski, Health Disparities : Weaving A New Understanding Through Case Narratives, Health Psychology, Journal Article, Medical Sociology, Medicine, Medicine & Public Health, NEOMED College of Medicine, November 2019 Update, Premedical Education, Social Work, Trust

Impact of the Optiwave Refractive Analysis in Post-LASIK Patients Undergoing Cataract Surgery

Tags: 2019, Department of General Surgery, Erzurum Sergul, Gemmel David, Investigative ophthalmology & visual science, Journal Article, Mercy Health St Elizabeth Youngstown Hospital, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Parikh Ankur A, Yalamanchili Siri

In-situ Coronary Thrombosis in Antiphospholipid Syndrome: A Case Report

Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disorder characterized by arterial and venous thrombosis, often accompanied by elevated titers of anti-phospholipid antibodies. Cardiac involvement in APS is not uncommon. However,…

Tags: 2019, Cureus, Department of Internal Medicine, Gopalakrishnan Prabhakaran, Journal Article, NEOMED College of Medicine, November 2019 Update, Pervez Hira, Rufus Sharan

Intestinal SIRT1 Deficiency Protects Mice from Ethanol-Induced Liver Injury by Mitigating Ferroptosis

Aberrant liver sirtuin 1 (SIRT1), a mammalian NAD+-dependent protein deacetylase, is implicated in the pathogenesis of alcoholic liver disease. However, the role of intestinal SIRT1 in alcoholic liver disease is presently unknown. This study…

Tags: 2019, Bonavita Gregory, Buehler Brian, Daniels Michael, DeCaro Elizabeth, Department of Pharmaceutical Sciences, Journal Article, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, November 2019 Update, Stahl Zachary, The American journal of pathology, Ye Ting Jie, You Min, Zhou Zhou

Is heart failure a coronary microvascular disorder?

Tags: 2019, Chilian W M, COMPRESSIVE force, Department of Integrative Medical Sciences, ENDOTHELIUM diseases, Enrick M, Gyulkhasyan T, Hakobyan T, Heart failure, Journal Article, Kolz C L, MICROCIRCULATION disorders, NEOMED College of Medicine, November 2019 Update, Ohanyan V, Proceedings Of The Physiological Society, Shockling L

Kidnapped

The translator and I arrived at a modest home in a neighborhood just outside of downtown. We were halfway through the interview process – at perhaps number 20 or 21 of the 45 we had planned to conduct. The neighborhood and home were much like the…

Tags: 2019, Culture, Health Disparities : Weaving A New Understanding Through Case Narratives, Health Psychology, Informed Consent, Journal Article, Kingsbury Diana M, Language, Medical Sociology, Medicine, Medicine & Public Health, NEOMED College of Medicine, NEOMED College of Medicine Postdoc, NEOMED Postdoc Publications, November 2019 Update, Premedical Education, Social Work

Kratom exposures reported to United States poison control centers: 2011–2017.

Context: Kratom, or Mitragyna speciosa, is a plant indigenous to Southeast Asia that has gained national attention in the United States for its increased use in the self-management of opioid withdrawal and pain, as well as for concerns about its…

Life Design: A Paradigm for Innovating Career Counselling in Global Context

More than a decade has elapsed since the original statement of life design as an innovative and internationally-constructed paradigm for careers science and practice. Responding to the challenges of work and career in contemporary times, life design…

Tags: 2019, Behavioral Science and Psychology, Career construction theory and counselling, Career development paradigms, career intervention, Career Skills, career theory, Counselling and Interpersonal Skills, Department of Family & Community Medicine, Globalization, Handbook Of Innovative Career Counselling, Hartung Paul J, Journal Article, life designing, NEOMED College of Medicine, November 2019 Update, Psychology

Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis

Macrophages play a crucial role in the pathogenesis of atherosclerosis, but the molecular mechanisms remain poorly understood. Here we show that microRNA-34a (miR-34a) is a key regulator of macrophage cholesterol efflux and reverse cholesterol…

Morphological and masticatory performance variation of mouth behavior groups

Food texture preference and product acceptance are hypothesized to be influenced by mouth behavior. Recent work identified four mouth behavior (MB) groups that describe most consumers in the United States: Chewers, Crunchers, Smooshers, and Suckers.…

Tags: 2019, Beckley Jacqueline, Department of Anatomy & Neurobiology, Foegeding E Allen, food texture, Franks Erin M, Jeltema Melissa, Journal Article, Journal of Texture Studies, Luck Paige J, masticatory performance, morphological variation, mouth behavior, NEOMED College of Medicine, NEOMED College of Medicine Postdoc, NEOMED Postdoc Publications, November 2019 Update, Vinyard Christopher J

Narrative counseling

This chapter explains how practitioners use narrative psychology to help clients revise their career stories to increase comprehension, coherence, and continuity. Narrative therapy is an umbrella term that encompasses a variety of approaches to…

Neovascular Glaucoma Presenting Characteristics in a Referral-based Setting

Tags: 2019, Chandra Rohit, Fill Lauren, Gan Jenny, Giltner Angela, Investigative ophthalmology & visual science, Journal Article, Miller Chase W, Miller David G, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Pendergast Scott D

New in Town

This is a story of three patients seen by a newly licensed physician shortly after completing residency training. The physician was born, raised, and educated in the northeastern United States before moving to Texas where he was unprepared to handle…

Non-operative management of spinal metastases: A prognostic model for failure

OBJECTIVES: To describe patient-specific characteristics associated with non-operative failure leading to surgery. PATIENTS AND METHODS: We conducted a retrospective review of patients treated for spinal metastases from 2005 to 2017. We deemed…

Nose-to-brain co-delivery of repurposed simvastatin and BDNF synergistically attenuates LPS-induced neuroinflammation

A therapeutic strategy that can combat the multifaceted nature of neuroinflammation pathology was investigated. Thus, we fabricated PEG-PdLLA polymersomes and evaluated the efficacy in co-delivery of simvastatin (Sim, as a repurposed…

Tags: 2019, And Medicine, Biology, Department of Pharmaceutical Sciences, Drug repurposing, Intranasal delivery, Journal Article, Lin Li, Manickavasagam Dharani, Microglia, Nanomedicine: Nanotechnology, Nanomedicine: Nanotechnology, Biology, And Medicine, Nanoparticles, NEOMED College of Pharmacy, NEOMED College of Pharmacy Student, NEOMED Student Publications, November 2019 Update, Oyewumi Moses O, polymersomes

Novel automated processing technique for standardization and normalization of fluorescein angiography images in patients with uveitis

Tags: 2019, Investigative ophthalmology & visual science, Journal Article, Kesav Natasha Preethi, Losert Wolfgang, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Sen H Nida, Yang Qixin

Nutritionally Variant Streptococcal Bacteremia in the 21st Century Report of 26 Episodes for a 12-Year Period (2006-2017) at a Large Community Teaching Hospital and Review of the Literature

We report the results of a 12-year retrospective study of nutritionally variant streptococcal (NVS) bacteremia in a 510-bed, a large medical school-affiliated teaching hospital. Twenty-six episodes of NVS bacteremia were identified in this…

Tags: 2019, Department of Internal Medicine, Infectious Diseases in Clinical Practice, Journal Article, Myers Joseph P, NEOMED College of Medicine, November 2019 Update, Summa Health System Akron City Hospital, Wright Edward A

Ovarian torsion

A twisting of the ovary and/or fallopian tube on its vascular and ligamentous supports, blocking adequate blood flow to the ovary. Rapid diagnosis and intervention are necessary to preserve ovarian function. Most often seen in women of reproductive…

Tags: 2019, adnexal torsion, Aultman Hospital, Department of Obstetrics & Gynecology, Fallopian tube torsion, Jay R Patibandla MD, Journal Article, Michael P Hopkins MD MEd, NEOMED College of Medicine, November 2019 Update, Tubal torsion

Pancreatoduodenectomy in patient with perforated duodenal diverticulum and peritonitis: Case report

INTRODUCTION: Duodenal diverticula are quite prevalent in general population, seen on up to 5% of radiology studies and up to 22% of autopsy examinations. PRESENTATION OF THE CASE: 70 years old female was admitted to the hospital with epigastric…

Tags: 2019, Cocieru Andrei, Department of General Surgery, International Journal Of Surgery Case Reports, Journal Article, NEOMED College of Medicine, November 2019 Update, Philip Justus

Pediatric Migraine Action Plan (PedMAP)

Pre-degenerative Accumulation of Superoxide and Hydroxide in a Chronic Mouse Model of Glaucoma

Tags: 2019, Department of Pharmaceutical Sciences, Inman Denise M, Investigative ophthalmology & visual science, Jassim Assraa Hassan, Journal Article, NEOMED College of Graduate Studies, NEOMED College of Graduate Studies Student, NEOMED College of Pharmacy, November 2019 Update

Premature birth impacts bolus size and shape through nursing in infant pigs

BACKGROUND: The formation of a bolus of food is critical for proper feeding function, and there is substantial variation in the size and shape of a bolus prior to a swallow. Preterm infants exhibit decreased abilities to acquire and process food, but…

Tags: 2019, Bond Laura E, Department of Anatomy & Neurobiology, German Rebecca Z, Gould Francois D H, Journal Article, Mayerl Christopher J, Myrla Alexis M, NEOMED College of Medicine, NEOMED College of Medicine Postdoc, NEOMED Postdoc Publications, November 2019 Update, Pediatric Research, Stricklen Bethany M

Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264.7 cells

Inflammation is a complex physiological process that poses a serious threat to people's health. However, the potential molecular mechanisms of inflammation are still not clear. Moreover, there is lack of effective anti-inflammatory drugs that meet…

Tags: 2019, Chen Shaoru, Department of Integrative Medical Sciences, Du Li-Jun, Feng Jianfang, Gao Hongwei, Han Shan, Journal Article, Li Jun, Li Jun-Xiu, Li Xinxing, Luo Ying-Ying, NEOMED College of Medicine, November 2019 Update, Scientific reports, Wang Qinqin, Yang Shilin, Zhao Li-Chun

Psychotic disorders in late life: a narrative review

Psychotic disorders are not uncommon in late life. These disorders often have varied etiologies, different clinical presentations, and are associated with significant morbidity and mortality among the older adult population. Psychotic disorders in…

Radiomic characterization of perirectal fat on MRI enables accurate assessment of tumor regression and lymph node metastasis in rectal cancers after chemoradiation

Evaluating tumor regression of rectal cancers via MRI after standard-of-care chemoradiation therapy (CRT) remains highly challenging for radiologists. While the tumor region-of-interest (ROI) on post-CRT rectal MRI is difficult to localize, an…

Recognition Sites for Cancer-Targeting Durg Delivery Systems

BACKGROUND: Target-homing drug delivery systems are now gaining significant traction for use as novel therapeutic approaches in antitumor targeting for cancer therapy. Numerous targeted drug delivery systems have been designed to improve the…

Tags: 2019, Anhui Medical University, Bao Jianwei, Current Drug Metabolism, Czech Tori, Department of Pharmaceutical Sciences, Guan Siyu, Hu Rongfeng, Journal Article, ligand, Nanoparticles, NEOMED College of Pharmacy, NEOMED College of Pharmacy Student, November 2019 Update, Recognition sites, Tang Jihui, targeted drug delivery system, Tumor, Zhang Qianqian

Reducing Surgical Site Infection (SSI) in Colorectal Surgery by Implementing Postoperative Intervention: A Multi-Center Experience

Tags: 2019, DeVito Robert, Hubert James, Journal Article, Journal of the American College of Surgeons, Kimyaghalam Ali, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Phillips Kyle, Scientific poster presentations

Results through skeletal maturity of planned fibular nonunion for the treatment of genu varum in achondroplasia: An observational retrospective study

Current surgical options for treating genu varum in achondroplasia include tibial and fibular osteotomy and growth modulation using plates and screws. However, a single surgeon consistently treated genu varum using a planned fibular nonunion (PFN).…

Risk Stratification of Older Adults Who Present to the Emergency Department With Syncope: The FAINT Score

STUDY OBJECTIVE: Older adults with syncope are commonly treated in the emergency department (ED). We seek to derive a novel risk-stratification tool to predict 30-day serious cardiac outcomes. METHODS: We performed a prospective, observational study…

Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae.

In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE)…

Safe marginal resection of atypical neurofibromas in neurofibromatosis type 1

OBJECTIVE: Patients with neurofibromatosis type 1 (NF1) are predisposed to visceral neurofibromas, some of which can progress to premalignant atypical neurofibromas (ANFs) and malignant peripheral nerve sheath tumors (MPNSTs). Though subtotal…

Tags: 2019, ANF = atypical neurofibroma (neurofibroma with nuclear atypia), ANNUBP = atypical neurofibromatous neoplasm of uncertain biological potential, atypical neurofibroma, Benzo Sarah, Chittiboina Prashant, Dombi Eva, EMG = electromyographic, Hayes Christina, hgMPNST = high-grade MPNST, Journal Article, Journal of neurosurgery, Lehky Tanya J, lgMPNST = low-grade MPNST, marginal margin, Miettinen Markku M, MPNST = malignant peripheral nerve sheath tumor, NCI = National Cancer Institute, NCV = nerve conduction velocity, Nelson Charlie N, NEOMED College of Medicine Student, NEOMED Student Publications, neurofibromatosis 1, NF1 = neurofibromatosis type 1, NIH = National Institutes of Health, November 2019 Update, peripheral nerve, resection, Rosenblum Jared S, Scott Gretchen, Surgery, SUVMax = maximum SUV within the tumor, Whitcomb Patricia O, Widemann Brigitte C

Shaping of discrete auditory inputs to extramodular zones of the lateral cortex of the inferior colliculus

The multimodal lateral cortex of the inferior colliculus (LCIC) exhibits a modular-extramodular micro-organization that is evident early in development. In addition to a set of neurochemical markers that reliably highlight its modular-extramodular…

Tags: 2019, Brain structure & function, Compartments, Gabriele Mark L, immunocytochemistry, Journal Article, Lamb-Echegaray Isabel D, Mapping, Modularity, multimodal, NEOMED College of Medicine Student, NEOMED Student Publications, Noftz William A, November 2019 Update, Patch-matrix, Stinson Jeremiah P C, topography

Sharp Recanalization of a Chronically Occluded Superior Vena Cava in a Patient with Multiple Prior Peripherally Inserted Central Catheters.

Purpose: To present a unique case in which intravenous medications were administered intermittently through a peripherally inserted central catheter (PICC) line over 2 years in the presence of an occluded superior vena cava (SVC) due to impressive…

Sight for Kids: Improving the Vision of Children in an At-Risk Population

Tags: 2019, Erzurum Sergul, Investigative ophthalmology & visual science, Journal Article, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, November 2019 Update, Parikh Ankur A, Yalamanchili Siri, Yusuf Saidah

Specialty and Lifestyle Preference Changes during Medical School

Purpose: Medical student specialty choices have significant downstream effects on the availability of physicians and, ultimately, the effectiveness of health systems. This study investigated how medical student specialty preferences change over time…

Stalemate

My next patient to be seen during office hours is the typical one whose name is instantly recognizable and causes a shiver much like what a sour candy ball does to your mouth. The interaction is pleasurable enough, but the end result is always…

Tags: 2019, Addiction, Brian Bachelder, Clev eland Clinic Akron General Hosptial, Communication, Department of Family & Community Medicine, Health Disparities : Weaving A New Understanding Through Case Narratives, Health Psychology, Journal Article, Lung disease, Medical Sociology, Medicine, Medicine & Public Health, NEOMED College of Medicine, November 2019 Update, Poverty, Premedical Education, Social Work

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