1
40
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Text
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URL Address
<a href="http://doi.org/10.1177/0884533614539177" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/0884533614539177</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
636-638
Issue
5
Volume
29
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Efficacy and Safety of Using L-cysteine as a Catheter-Clearing Agent for Nonthrombotic Occlusions of Central Venous Catheters in Children
Publisher
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Nutrition in Clinical Practice
Date
A point or period of time associated with an event in the lifecycle of the resource
2014
2014-10
Subject
The topic of the resource
alteplase; catheter obstruction; catheters; central venous; ethanol; hydrochloric-acid; L-cysteine; Nutrition & Dietetics; occlusion; parenteral nutrition; tissue-plasminogen activator; trial
Creator
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Pai V B; Plogsted S
Description
An account of the resource
Critically ill pediatric patients, especially in the intensive care unit, receive multiple medications and have a higher risk of central venous catheter (CVC) occlusion. If an occlusion occurs immediately after the administration of multiple medications or incompatible medications, either an acidic solution such as 0.1 N hydrochloric acid (HCl) or a basic solution of 1 mEq/mL sodium bicarbonate or 0.1 N sodium hydroxide can be used. However, compounding and storing of 0.1 N HCl has become more complex due to USP <797> guidelines for sterile compounding, and an alternative is needed. We report a series of cases in which L-cysteine was used instead of HCl to clear CVCs occluded due to administration of multiple medications. L-cysteine is a commercially available, sterile solution with a pH of 1-2.5. CVC occlusion was resolved in 10 of the 16 episodes in 13 patients. Two of the 16 occlusions were phenytoin related and would not have responded. An L-cysteine dose of 50 mg was used during 10 of the 16 episodes, 100 mg during 5 episodes, and 25 mg during 1 episode. A correlation between catheter clearance and dose was not observed. Occlusion resolution due to L-cysteine was not correlated to the prior use of tissue plasminogen activator. Metabolic acidosis, adverse effects, or damage to the catheters due to L-cysteine were not observed. On the basis of this limited experience, we propose L-cysteine as an effective alternative to 0.1 N HCl for clearing CVC occlusions caused by drugs with an acidic pKa.
Identifier
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<a href="http://doi.org/10.1177/0884533614539177" target="_blank" rel="noreferrer noopener">10.1177/0884533614539177</a>
Format
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Journal Article
2014
alteplase
catheter obstruction
Catheters
Central Venous
ETHANOL
hydrochloric-acid
Journal Article
L-cysteine
Nutrition & Dietetics
Nutrition in Clinical Practice
occlusion
Pai V B
parenteral nutrition
Plogsted S
tissue-plasminogen activator
trial
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/0884533612463440" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/0884533612463440</a>
Pages
718–737
Issue
6
Volume
27
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Providing Nutrition Support in the Electronic Health Record Era: The Good, the Bad, and the Ugly.
Publisher
An entity responsible for making the resource available
Nutrition in Clinical Practice
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-12
Subject
The topic of the resource
Time Factors; Health Personnel; Nutritional Support; Safety; Human; Questionnaires; Descriptive Statistics; Summated Rating Scaling; Documentation; Electronic Order Entry; Product Evaluation; Acute Care; America; Electronic Health Records – Methods
Creator
An entity primarily responsible for making the resource
Vanek Vincent W
Identifier
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<a href="http://doi.org/10.1177/0884533612463440" target="_blank" rel="noreferrer noopener">10.1177/0884533612463440</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2012
Acute Care
America
Descriptive Statistics
Documentation
Electronic Health Records – Methods
Electronic Order Entry
Health Personnel
Human
Nutrition in Clinical Practice
Nutritional Support
Product Evaluation
Questionnaires
Safety
Summated Rating Scaling
Time Factors
Vanek Vincent W