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Impact of reirradiation of painful osseous metastases on quality of life and function: a secondary analysis of the NCIC CTG SC.20 randomized trial.

PURPOSE: We previously demonstrated that 48% of patients with pain at sites of previously irradiated bone metastases benefit from reirradiation. It is unknown whether alleviating pain also improves patient perception of quality of life (QOL).…

Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial.

BACKGROUND: Although repeat radiation treatment has been shown to palliate pain in patients with bone metastases from multiple primary origin sites, data for the best possible dose fractionation schedules are lacking. We aimed to assess two dose…

Tags: *Dose Fractionation, *Radiotherapy, 2014, Aged, Analgesics – Therapeutic Use, Analgesics/therapeutic use, Australia, Babington Scott, Bone Neoplasms, Bone Neoplasms – Complications, Bone Neoplasms – Radiotherapy, Bone Neoplasms/complications/*radiotherapy/*secondary, Brief pain inventory, Brundage Michael D, Canada, Cauda Equina, Chen Bingshu E, Chi Square Test, Chi-Square Distribution, Chow Edward, Clinical Assessment Tools, Clinical Trials, Computer-Assisted, Computer-Assisted – Adverse Effects, Computer-Assisted/adverse effects, Demas William F, Europe, Female, Fractures, Funding Source, Hartsell William F, Hoskin Peter, Human, Humans, Intention to Treat Analysis, Israel, Logistic Models, Logistic Regression, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, New Zealand, Odds Ratio, Oei Bing, Pain – Diagnosis, Pain – Drug Therapy, Pain – Etiology, Pain – Radiotherapy, Pain Measurement, Pain/diagnosis/drug therapy/*etiology/*radiotherapy, Questionnaires, Radiation, Radiation Dosage, Radiotherapy, Radiotherapy Planning, Risk Factors, Roos Daniel, Scales, Spinal Cord Compression – Etiology, Spinal Cord Compression/etiology, Spontaneous – Etiology, Spontaneous/etiology, Surveys and Questionnaires, The Lancet. Oncology, Time Factors, Tissing-Tan Caroline J A, Treatment Outcome, Treatment Outcomes, van der Linden Yvette M, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y

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