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                <text>The current lack of agreement regarding standardised terminology in musculoskeletal and sports ultrasound presents challenges in education, clinical practice and research. This consensus was developed to provide a reference to improve clarity and consistency in communication. A multidisciplinary expert panel was convened consisting of 18 members representing multiple specialty societies identified as key stakeholders in musculoskeletal and sports ultrasound. A Delphi process was used to reach consensus, which was defined as group level agreement of &gt;80%. Content was organised into seven general topics including: (1) general definitions, (2) equipment and transducer manipulation, (3) anatomical and descriptive terminology, (4) pathology, (5) procedural terminology, (6) image labelling and (7) documentation. Terms and definitions which reached consensus agreement are presented herein. The historic use of multiple similar terms in the absence of precise definitions has led to confusion when conveying information between colleagues, patients and third-party payers. This multidisciplinary expert consensus addresses multiple areas of variability in diagnostic ultrasound imaging and ultrasound-guided procedures related to musculoskeletal and sports medicine.</text>
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                <text>Objectives: The current lack of agreement regarding standardized terminology in musculoskeletal and sports ultrasound presents challenges in education, clinical practice, and research. This consensus was developed to provide a reference to improve clarity and consistency in communication.&#13;
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Methods: A multidisciplinary expert panel was convened consisting of 18 members representing multiple specialty societies identified as key stakeholders in musculoskeletal and sports ultrasound. A Delphi process was used to reach consensus which was defined as group level agreement &gt;80%.&#13;
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Results: Content was organized into seven general topics including: 1) General Definitions, 2) Equipment and Transducer Manipulation, 3) Anatomic and Descriptive Terminology, 4) Pathology, 5) Procedural Terminology, 6) Image Labeling, and 7) Documentation. Terms and definitions which reached consensus agreement are presented herein.&#13;
&#13;
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                <text>&lt;a href="http://doi.org/10.1080/03008200290001320" target="_blank" rel="noreferrer noopener"&gt;10.1080/03008200290001320&lt;/a&gt;</text>
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            <elementText elementTextId="135642">
              <text>26</text>
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              <text>571-582</text>
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              <text>4</text>
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            <elementText elementTextId="135175">
              <text>20</text>
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          <elementTextContainer>
            <elementText elementTextId="135176">
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            <description>A name given to the resource</description>
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            <name>Publisher</name>
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                <text>Orthopedic Clinics of North America</text>
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                <text>1989</text>
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            <name>Identifier</name>
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              <text>6</text>
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              <text>23</text>
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                <text>Jain R; Bredle D L; Helms S E; Brodell R T</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>n/a</text>
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            <name>Format</name>
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              <elementText elementTextId="133478">
                <text>Journal Article or Conference Abstract Publication</text>
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        <name>1995</name>
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        <name>Bredle D L</name>
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      <tag tagId="31">
        <name>Brodell R T</name>
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      <tag tagId="33741">
        <name>General &amp; Internal Medicine</name>
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      <tag tagId="116">
        <name>Helms S E</name>
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      <tag tagId="19662">
        <name>Jain R</name>
      </tag>
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        <name>Journal Article or Conference Abstract Publication</name>
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      <tag tagId="2763">
        <name>Orthopedics</name>
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      <tag tagId="41251">
        <name>Physician and Sportsmedicine</name>
      </tag>
      <tag tagId="34696">
        <name>Sport Sciences</name>
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            <elementText elementTextId="133177">
              <text>&lt;a href="http://doi.org/10.1016/j.jse.2010.02.010" target="_blank" rel="noreferrer noopener"&gt;http://doi.org/10.1016/j.jse.2010.02.010&lt;/a&gt;</text>
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          <elementTextContainer>
            <elementText elementTextId="133178">
              <text>Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).</text>
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          </elementTextContainer>
        </element>
        <element elementId="55">
          <name>Pages</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="133179">
              <text>1243-1249</text>
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          <description/>
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            <elementText elementTextId="133180">
              <text>8</text>
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        <element elementId="57">
          <name>Volume</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="133181">
              <text>19</text>
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          <name>Search for Full-text</name>
          <description>Locate full-text within NEOMED Library's e-journal collections</description>
          <elementTextContainer>
            <elementText elementTextId="133182">
              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="133169">
                <text>Agreement Study Of Radiographic Classification Of Rotator Cuff Tear Arthropathy</text>
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          <element elementId="45">
            <name>Publisher</name>
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              <elementText elementTextId="133170">
                <text>Journal of Shoulder and Elbow Surgery</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="133171">
                <text>2010</text>
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              <elementText elementTextId="133172">
                <text>2010-12</text>
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          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="133173">
                <text>classification; clinical decision making; inter-rater and; intra-rater reliability; Orthopedics; Rotator cuff tear arthropathy; Sport Sciences; Surgery; total shoulder arthroplasty</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="133174">
                <text>Iannotti J P; McCarron J; Raymond C J; Ricchetti E T; Abboud J A; Brems J J; Williams G R</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="133175">
                <text>Hypothesis: This study evaluated the intra-rater and inter-rater correlation of 3 commonly used x-ray image classifications and defined the clinical factors most correlated with a surgical recommendation for a hemiarthroplasty or a reverse total shoulder arthroplasty (RSA) for treatment of rotator cuff tear arthropathy (CTA). We hypothesized that specific radiographic criteria and clinical criteria would be most important and consistently used among experienced shoulder surgeons when determining the best surgical option for a particular patient. Methods: Four experienced orthopedic surgeons evaluated standard anteroposterior radiographs and the clinical examination of 37 shoulders with CTA. On each reading, they classified the grade of pathology using the Seebauer, Favard, and Hamada classifications. Using radiographic criteria alone, or with the clinical findings, each evaluator determined the recommended prosthetic treatment for each shoulder. Results: Intra-rater correlations for surgical recommendations using radiographic criteria ranged from 0.39 to 1.0 and improved in 3 of 4 evaluators when the clinical examination was included in the clinical decision. The inter-rater reliability using these same criteria were fair, at 0.32 for radiographic and .35 for radiographic and clinical data. The most significant radiographic factors associated with a surgical decision were the degree of humeral head superior migration and the escape of the humeral head from the coracoa-cromial arch. Clinical factors most associated with the decision for RSA were advanced age, loss of shoulder elevation, superior humeral head escape, and pseudoparalysis of the shoulder. Radiographic findings had a less significant effect on surgical recommendations when clinical factors were included. Conclusion: Clinical and radiographic criteria are needed for a decision for hemiarthroplasty or RSA in the treatment of CTA. A treatment algorithm based upon radiographic and clinical criteria is proposed.</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="133176">
                <text>&lt;a href="http://doi.org/10.1016/j.jse.2010.02.010" target="_blank" rel="noreferrer noopener"&gt;10.1016/j.jse.2010.02.010&lt;/a&gt;</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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              <elementText elementTextId="133183">
                <text>Journal Article or Conference Abstract Publication</text>
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        <name>Abboud J A</name>
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        <name>Brems J J</name>
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        <name>classification</name>
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        <name>clinical decision making</name>
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        <name>Iannotti J P</name>
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        <name>inter-rater and</name>
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        <name>intra-rater reliability</name>
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      <tag tagId="41733">
        <name>Journal Article or Conference Abstract Publication</name>
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      <tag tagId="7709">
        <name>Journal of shoulder and elbow surgery</name>
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        <name>McCarron J</name>
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        <name>Orthopedics</name>
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        <name>Raymond C J</name>
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        <name>Ricchetti E T</name>
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      <tag tagId="48385">
        <name>Rotator cuff tear arthropathy</name>
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      <tag tagId="34696">
        <name>Sport Sciences</name>
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        <name>Surgery</name>
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        <name>total shoulder arthroplasty</name>
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        <name>Williams G R</name>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <element elementId="53">
          <name>URL Address</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="132763">
              <text>&lt;a href="http://doi.org/10.1007/s00264-008-0621-0" target="_blank" rel="noreferrer noopener"&gt;http://doi.org/10.1007/s00264-008-0621-0&lt;/a&gt;</text>
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          </elementTextContainer>
        </element>
        <element elementId="54">
          <name>Rights</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="132764">
              <text>Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).</text>
            </elementText>
          </elementTextContainer>
        </element>
        <element elementId="55">
          <name>Pages</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="132765">
              <text>765-771</text>
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        </element>
        <element elementId="56">
          <name>Issue</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="132766">
              <text>3</text>
            </elementText>
          </elementTextContainer>
        </element>
        <element elementId="57">
          <name>Volume</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="132767">
              <text>33</text>
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        </element>
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          <name>Search for Full-text</name>
          <description>Locate full-text within NEOMED Library's e-journal collections</description>
          <elementTextContainer>
            <elementText elementTextId="132768">
              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132755">
                <text>Dynamic Skeletal Traction Spica Casts For Paediatric Femoral Fractures In A Resource-limited Setting</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="132756">
                <text>International Orthopaedics</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132757">
                <text>2009</text>
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              <elementText elementTextId="132758">
                <text>2009-06</text>
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          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132759">
                <text>adolescents; children; femur fractures; flexible intramedullary nails; internal-fixation; operative stabilization; Orthopedics; shaft fractures</text>
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            </elementTextContainer>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132760">
                <text>Hsu A R; Diaz H M; Penaranda N R P; Cui H D; Evangelista R H A; Rinsky L; Gracilla R V</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132761">
                <text>The objective of this study was to compare elastic intramedullary nailing (EIN) with dynamic skeletal traction spica casting (DSTSC) in terms of postoperative radiographic angulations, length of hospital stay, and cost in a resource-limited setting. We prospectively studied 51 children, five to twelve years of age, with femoral fractures treated with either EIN (n = 26) or DSTSC (n = 25). Children treated with EIN had significantly longer hospital stays (17 +/- 8.0 days) than those treated with DSTSC (6.0 +/- 2.5 days). Financial constraints in acquiring supplies caused a significant increase in time from admission to surgery (EIN 9.5 +/- 2.3 days; DSTSC 1.1 +/- 0.3 days), and cost was about 400% higher for EIN compared with DSTSC. At twelve weeks follow-up, all patients in both groups had acceptable radiographic angulations. In resource-limited healthcare settings, DSTSC is an effective alternative to EIN with comparable post-op radiographic angulations, decreased hospital stays, and lower cost.</text>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="132762">
                <text>&lt;a href="http://doi.org/10.1007/s00264-008-0621-0" target="_blank" rel="noreferrer noopener"&gt;10.1007/s00264-008-0621-0&lt;/a&gt;</text>
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            <name>Format</name>
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            <elementTextContainer>
              <elementText elementTextId="132769">
                <text>Journal Article or Conference Abstract Publication</text>
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      <tag tagId="19064">
        <name>adolescents</name>
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      <tag tagId="3064">
        <name>Children</name>
      </tag>
      <tag tagId="48266">
        <name>Cui H D</name>
      </tag>
      <tag tagId="47402">
        <name>Diaz H M</name>
      </tag>
      <tag tagId="48267">
        <name>Evangelista R H A</name>
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      <tag tagId="48260">
        <name>femur fractures</name>
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        <name>flexible intramedullary nails</name>
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      <tag tagId="47401">
        <name>Gracilla R V</name>
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      <tag tagId="48264">
        <name>Hsu A R</name>
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      <tag tagId="38382">
        <name>internal-fixation</name>
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      <tag tagId="47396">
        <name>International Orthopaedics</name>
      </tag>
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        <name>Journal Article or Conference Abstract Publication</name>
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        <name>operative stabilization</name>
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        <name>Orthopedics</name>
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        <name>Penaranda N R P</name>
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      <tag tagId="48268">
        <name>Rinsky L</name>
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      <tag tagId="48263">
        <name>shaft fractures</name>
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  <item itemId="10167" public="1" featured="1">
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
      <elementContainer>
        <element elementId="53">
          <name>URL Address</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="131516">
              <text>&lt;a href="http://doi.org/10.1097/01.bpo.0000188994.90931.e8" target="_blank" rel="noreferrer noopener"&gt;http://doi.org/10.1097/01.bpo.0000188994.90931.e8&lt;/a&gt;</text>
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        <element elementId="54">
          <name>Rights</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="131517">
              <text>Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).</text>
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          </elementTextContainer>
        </element>
        <element elementId="55">
          <name>Pages</name>
          <description/>
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            <elementText elementTextId="131518">
              <text>91-93</text>
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        <element elementId="56">
          <name>Issue</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="131519">
              <text>1</text>
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        <element elementId="57">
          <name>Volume</name>
          <description/>
          <elementTextContainer>
            <elementText elementTextId="131520">
              <text>26</text>
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          <name>Search for Full-text</name>
          <description>Locate full-text within NEOMED Library's e-journal collections</description>
          <elementTextContainer>
            <elementText elementTextId="131521">
              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="131508">
                <text>Histologic And Histochemical Analysis Of Muscle Specimens In Idiopathic Talipes Equinovarus</text>
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          <element elementId="45">
            <name>Publisher</name>
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              <elementText elementTextId="131509">
                <text>Journal of Pediatric Orthopaedics</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2006</text>
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                <text>2006-01</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="131512">
                <text>club foot; club foot; congenital clubfoot; etiology; histochemistry; muscle biopsy; Orthopedics; pathogenesis; Pediatrics</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="131513">
                <text>Herceg M B; Weiner D S; Agamanolis D P; Hawk D</text>
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          <element elementId="41">
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            <description>An account of the resource</description>
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              <elementText elementTextId="131514">
                <text>Congenital idiopathic talipes equinovarus is a relatively common disorder of uncertain etiology with a wide variance of clinical severity. Many theories have been postulated over the years without universal agreement in regard to the cause of this disorder. These hypotheses include vascular, viral, genetic, anatomic, compartment syndrome, environmental,(13) and positioning considerations.` A great deal of recent discussion has focused on a neuromuscular etiology for this condition. Muscle biopsies from the gastrocnermus, abductor hallucis, flexor digitorum longus, flexor hallucis, and tibialis posterior were obtained during posteromedial surgical release for idiopathic talipes equinovarus from September 1994 to October 2000 at the authors' institution. Ninety-five feet in 68 patients yielded a total of 431 muscle specimens. All of the specimens were processed and examined by light microscopy by an expert neuromuscular pathologist. In addition, 95 tissue samples were further processed for histochemical studies and electron microscopy. Three hundred seventy-two specimens (86.3%) showed no evidence of a pathologic diagnosis with normal fiber-type ratios and no type I fiber grouping indicative of neuromuscular pathology. Only 4 specimens (0.9%) showed type I fiber predominance, and 55 specimens (12.8%) revealed muscle fiber atrophy. The results of this study do not support the theory that a neurormiscular abnormality may be significant in the etiology of idiopathic talipes equinovarus.</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>&lt;a href="http://doi.org/10.1097/01.bpo.0000188994.90931.e8" target="_blank" rel="noreferrer noopener"&gt;10.1097/01.bpo.0000188994.90931.e8&lt;/a&gt;</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="131522">
                <text>Journal Article or Conference Abstract Publication</text>
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        <name>2006</name>
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        <name>muscle biopsy</name>
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        <name>Pathogenesis</name>
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        <name>Pediatrics</name>
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        <name>Weiner D S</name>
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              <text>654-657</text>
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              <text>24</text>
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              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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                <text>Remodeling Of The Proximal Femur After Upper Femoral Varus Osteotomy For The Treatment Of Legg-calve-perthes Disease</text>
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                <text>catterall classification; children; deformity; femoral remodeling; fractures; head; lateral pillar classification; Legg-Calve-Perthes disease; operation; Orthopedics; osteotomy; Pediatrics; prognosis; shaft; valgus derotation</text>
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                <text>Upper femoral varus osteotomy of the proximal femur without rotation has been the surgical treatment of choice by the senior author (D.S.W) in 124 cases of Legg-Calve-Perthes disease. There have been no previous studies documenting the nature of the remodeling process after this surgical procedure. The authors analyzed the radiographic changes that occur over time at the osteotomy site and the angle of inclination (neck-shaft angle). Inclusion criteria were a minimum of 2 years of radiographic follow-up. Patient follow-up ranged from 2 to 7 years (average 5.3 years). Goniometric measurements were performed at the osteotomy site as well as on the neck-shaft angle on preoperative, postoperative, and yearly AP radiographs. Results were recorded with reference to the percentage of correction per year. The authors also compared the results of patients younger than 8 years of age (group 1) with those older than 8 years of age (group 2). The average percentage of remodeling at the osteotomy site was 60% at 6 years, with 40% of the correction occurring within the first 2 years. The neck-shaft angle remodeled in a similar fashion: there was approximately two-thirds correction by 7 years, with most correction being evidenced within 3 to 4 years. There was no significant difference in remodeling based on the age of the patient at presentation. In conclusion, radiographically significant remodeling is to be expected after femoral varus osteotomy despite the diseased proximal femoral epiphysis.</text>
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        <name>Journal of Pediatric Orthopaedics</name>
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        <name>Legg-Calve-Perthes disease</name>
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        <name>Prognosis</name>
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        <name>shaft</name>
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        <name>valgus derotation</name>
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              <text>&lt;a href="http://doi.org/10.1097/00003086-198509000-00026" target="_blank" rel="noreferrer noopener"&gt;http://doi.org/10.1097/00003086-198509000-00026&lt;/a&gt;</text>
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            <elementText elementTextId="131032">
              <text>Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).</text>
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          <name>Pages</name>
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              <text>179-183</text>
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            <elementText elementTextId="131034">
              <text>198</text>
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              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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                <text>The Diagnostic-accuracy Of Spinal Nerve Injection Studies - Their Role In The Evaluation Of Recurrent Sciatica</text>
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                <text>Clinical Orthopaedics and Related Research</text>
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                <text>Haueisen D C; Smith B S; Myers S R; Pryce M L</text>
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                <text>&lt;a href="http://doi.org/10.1097/00003086-198509000-00026" target="_blank" rel="noreferrer noopener"&gt;10.1097/00003086-198509000-00026&lt;/a&gt;</text>
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              <text>&lt;a href="http://doi.org/10.1016/j.joca.2015.02.910" target="_blank" rel="noreferrer noopener"&gt;http://doi.org/10.1016/j.joca.2015.02.910&lt;/a&gt;</text>
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            <elementText elementTextId="130965">
              <text>A155-A156</text>
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            <elementText elementTextId="130966">
              <text>23</text>
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              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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                <text>A Small Molecule Harpagoside Inhibits Il-1beta-induced Expression Of Il-6 By Blocking The Expression Of C-fos In Primary Human Osteoarthritis Chondrocytes</text>
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                <text>Osteoarthritis and Cartilage</text>
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                <text>2015-04</text>
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                <text>Orthopedics; Rheumatology</text>
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                <text>Haseeb A; Leigh D; Haqqi T M</text>
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                <text>&lt;a href="http://doi.org/10.1016/j.joca.2015.02.910" target="_blank" rel="noreferrer noopener"&gt;10.1016/j.joca.2015.02.910&lt;/a&gt;</text>
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              <text>&lt;a href="http://doi.org/10.1016/j.joca.2013.02.053" target="_blank" rel="noreferrer noopener"&gt;http://doi.org/10.1016/j.joca.2013.02.053&lt;/a&gt;</text>
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              <text>21</text>
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          <description>Locate full-text within NEOMED Library's e-journal collections</description>
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              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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                <text>Il-1 Beta And Tnf-alpha Regulate The Global Hydroxymethylation Of Genomic Dna By Modulating The Expression And Activity Of Tet-1 In Human Oa Chondrocytes</text>
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                <text>Osteoarthritis and Cartilage</text>
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                <text>2013</text>
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                <text>2013-04</text>
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              <text>5</text>
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                <text>Modification Of Osteoarthritis In The Guinea Pig With Pulsed Low-intensity Ultrasound Treatment</text>
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                <text>aggrecan; articular-cartilage; cartilage; Cartilage repair; degeneration; double-blind trial; electromagnetic-fields; gene-expression; in-vitro; knee osteoarthritis; matrix production; Orthopedics; osteoarthritis; placebo-controlled trials; Rheumatology; therapeutic ultrasound; tissue engineered cartilage; Ultrasound</text>
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                <text>Gurkan I; Ranganathan A; Yang X; Horton W E; Todman M; Huckle J; Pleshko N; Spencer R G</text>
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                <text>Objective: The Hartley guinea pig develops articular cartilage degeneration similar to that seen in idiopathic human osteoarthritis (OA). We investigated whether the application of pulsed low-intensity ultrasound (PLIUS) to the Hartley guinea pig joint would prevent or attenuate the progression of this degenerative process. Methods: Treatment of male Hartley guinea pigs was initiated at the onset of degeneration (8 weeks of age) to assess the ability of PLIUS to prevent OA, or at a later age (12 months) to assess the degree to which PLIUS acted to attenuate the progression of established disease. PLIUS (30 mW/cm(2)) was applied to stifle joints for 20 min/day over periods ranging from 3 to 10 months, with contralateral limbs serving as controls. Joint cartilage histology was graded according to a modified Mankin scale to evaluate treatment effect. Immunohistochemical staining for interleukin-1 receptor antagonist (IL-1ra), matrix metalloproteinase (MMP)-3, MMP-13, and transforming growth factor (TGF)-beta 1 was performed on the cartilage to evaluate patterns of expression of these proteins. Results: PLIUS did not fully prevent cartilage degeneration in the prevention groups, but diminished the severity of the disease, with the treated joints showing markedly decreased surface irregularities and a much smaller degree of loss of matrix staining as compared to controls. PLIUS also attenuated disease progression in the groups with established disease, although to a somewhat lesser extent as compared to the prevention groups. Immunohistochemical staining demonstrated a markedly decreased degree of TGF-beta 1 production in the PLIUS-treated joints. This indicates less active endogenous repair, consistent with the marked reduction in cartilage degradation. Conclusions: PLIUS exhibits the ability to attenuate the progression of cartilage degeneration in an animal model of idiopathic human OA. The effect was greater in the treatment of early, rather than established, degeneration. Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International.</text>
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        <name>Yang X</name>
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              <text>&lt;a href="http://doi.org/10.1016/j.joca.2018.02.354" target="_blank" rel="noreferrer noopener"&gt;http://doi.org/10.1016/j.joca.2018.02.354&lt;/a&gt;</text>
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              <text>S162-S163</text>
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            <elementText elementTextId="129258">
              <text>26</text>
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                <text>Human Chondrocytes With Oxidative And Er Stress Inhibit Protein Synthesis By Induction Of Trna Fragments From A Subset Of Trna Isotypes Independent Of Angiogenin Expression And Activity</text>
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                <text>Osteoarthritis and Cartilage</text>
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                <text>Orthopedics; Rheumatology</text>
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                <text>Green J; Khan N M; Ansari M Y; Ahmad I; Novak K; Haqqi T M</text>
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                <text>&lt;a href="http://doi.org/10.1016/j.joca.2018.02.354" target="_blank" rel="noreferrer noopener"&gt;10.1016/j.joca.2018.02.354&lt;/a&gt;</text>
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              <text>145-148</text>
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              <text>3</text>
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              <text>27</text>
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              <text>&lt;p&gt;Users with a NEOMED Library login can search for full-text journal articles at the following url: &lt;a href="https://libraryguides.neomed.edu/home"&gt;https://libraryguides.neomed.edu/home&lt;/a&gt;&lt;/p&gt;</text>
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                <text>Traction Spica Cast For Femoral-shaft Fractures In Children</text>
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                <text>closed reduction; external; fixation; immobilization; long-term; nails; Orthopedics; pediatric femur fractures; skeletal traction; supracondylar kirschner wires</text>
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                <text>We treated 20 children for an isolated femoral shaft fracture using distal tibial traction incorporated into a spica cast with the knee in full extension. Patients were discharged from the hospital at a mean of 5.1 days following injury. All fractures healed, and there were four minor complications. At a mean follow-up of 35 (13-72) months, all patients were asymptomatic with normal function. All but one fracture healed in acceptable alignment, and there was no clinically significant leg-length discrepancy. The method is relatively simple to employ and may be advantageous in a setting of limited resources.</text>
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