Browse Items (21 total)
- Tags: Oyewumi Moses O
Biocompatibility and in vivo tolerability of a new class of photoresponsive alkoxylphenacyl-based polycarbonates.
Tags: 2013, Alanine Transaminase/blood, Animals, Biocompatible Materials/chemistry/*metabolism/*toxicity, Cell Line, Chamsaz Elaheh A, Creatine/blood, Cytokines/analysis, Department of Pharmaceutical Sciences, Erythrocytes/drug effects, Hemolysis/drug effects, Inbred BALB C, Journal of pharmaceutical sciences, Joy Abraham, Kidney/drug effects/pathology, Light, Liver/drug effects/pathology, Macrophages/cytology/drug effects, Mice, NEOMED College of Pharmacy, Oyewumi Moses O, Polycarboxylate Cement/chemistry/*metabolism/*toxicity, Rats, Sprague-Dawley, Sun Shuangyi, Wehrung Daniel
Contributory roles of innate properties of cetyl alcohol/gelucire nanoparticles to antioxidant and anti-inflammation activities of quercetin.
Screening and identification of novel compounds with potential anti-proliferative effects on gallium-resistant lung cancer through an AXL kinase pathway.
Tags: 2014, Alazizi Adnan, Antineoplastic Agents/chemical synthesis/chemistry/*pharmacology, Antitumor, AXL, Bioorganic & medicinal chemistry letters, Cell Line, Cell Proliferation/drug effects, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Drug Resistance, Drug Screening Assays, Gallium, Gallium-resistance, Gallium/pharmacology, Geldenhuys Werner J, Humans, Lin Li, Liva Sophia, Lung cancer, Lung Neoplasms/drug therapy/*enzymology/*pathology, Molecular Structure, Naphthalenes/chemistry/*pharmacology, NEOMED College of Pharmacy, Neoplasm/drug effects, Oyewumi Moses O, Proto-Oncogene Proteins/*antagonists & inhibitors/metabolism, Pyrazoles/chemistry/*pharmacology, Quinolines/chemistry/*pharmacology, Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors/metabolism, Structure-Activity Relationship, Tetrazoles/chemistry/*pharmacology, Tumor, Virtual screening
Effects of gelucire content on stability, macrophage interaction and blood circulation of nanoparticles engineered from nanoemulsions.
Tags: 2012, Animals, ATP Binding Cassette Transporter, Calorimetry, Colloids and surfaces. B, Biointerfaces, Department of Pharmaceutical Sciences, Differential Scanning, Drug Carriers/*chemical synthesis/pharmacokinetics, Drug Stability, Emulsions/chemistry, Fatty Alcohols/*chemistry, Fourier Transform Infrared, Geldenhuys Werner J, Humans, Inbred BALB C, Macrophages/*drug effects/metabolism, Member 1/metabolism, Mice, Nanoparticles/*chemistry/ultrastructure, NEOMED College of Pharmacy, Oils/chemistry, Oyewumi Moses O, Paclitaxel/pharmacokinetics, Particle Size, Polyethylene Glycols/*chemistry, Reactive Oxygen Species/metabolism, Rhodamine 123/metabolism, Spectroscopy, Subfamily B, Water/chemistry, Wehrung Daniel
Formulation and photoirradiation parameters that influenced photoresponsive drug delivery using alkoxylphenacyl-based polycarbonates.
Tags: 2014, Animals, Biocompatibility, Cardiotoxicity, Cell Line, Chamsaz Elaheh A, Chemistry, Department of Pharmaceutical Sciences, Dose-Response Relationship, Doxorubicin, Drug, Drug Delivery Systems/*methods, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Heart/drug effects, Humans, Inbred BALB C, Joy Abraham, Mice, Nanotechnology, NEOMED College of Pharmacy, Oyewumi Moses O, Pharmaceutical, Photic Stimulation/*methods, Photoresponsive, Photosensitizing Agents/*chemical synthesis/radiation effects/toxicity, Polycarboxylate Cement/*chemical synthesis/radiation effects/toxicity, Polymer chain scission, Stimuli-responsive, Tumor, Wehrung Daniel
Assessment of alkoxylphenacyl-based polycarbonates as a potential platform for controlled delivery of a model anti-glaucoma drug.
Tags: *Models, 2016, Animals, Bouhenni Rachida, Brimonidine tartrate, Chamsaz Elaheh A, Crish Samuel D, Department of Pharmaceutical Sciences, Drug delivery, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Glaucoma/*drug therapy, Humans, Joy Abraham, Manickavasagam Dharani, Nanoparticles, NEOMED College of Pharmacy, Ocular microfilms, Oyewumi Moses O, Polycarboxylate Cement/*therapeutic use, Rats, Sanders Matthew, Sustained release, Theoretical, Wehrung Daniel
Preparation of emulsifying wax/glyceryl monooleate nanoparticles and evaluation as a delivery system for repurposing simvastatin in bone regeneration.
Tags: 2018, Animals, Bone, Bone Regeneration/*drug effects/physiology, Czech Tori, Department of Pharmaceutical Sciences, Drug delivery, Drug Delivery Systems/*methods, Drug development and industrial pharmacy, Drug Evaluation, Drug Repositioning/methods, Emulsifying Agents/administration & dosage/*chemical synthesis, Eskinazi-Budge Aaron, Glycerides/administration & dosage/*chemical synthesis, Kunzler James, Manickavasagam Dharani, Mice, nanoemulsions, Nanoparticles, Nanoparticles/administration & dosage/*chemistry, NEOMED College of Pharmacy, Novak Kimberly, Osteoblasts, Osteoblasts/drug effects/physiology, Osteoclasts, Oyewumi Moses O, Preclinical/methods, RAW 264.7 Cells, Simvastatin/administration & dosage/*chemical synthesis, Waxes/chemical synthesis/pharmacology
Critical assessment of implantable drug delivery devices in glaucoma management.
Emerging lung cancer therapeutic targets based on the pathogenesis of bone metastases.
Requisite Role of Kv1.5 Channels in Coronary Metabolic Dilation.
Tags: 129 Strain, 2015, Animals, Bardakjian Raffi, Bratz Ian, Cardiac function, Chilian William M, Circulation research, contrast echocardiography, Coronary Circulation/*physiology, Coronary Vessels/*metabolism, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Enrick Molly, Fu Frances Kwan, Graham Jacqueline, Hakobyan Tatevik, Hou Huagang, Hydrogen peroxide, Inbred C57BL, ion channel, Janota Danielle, Khan Nadeem, Kmetz John, Knockout, Kolz Christopher, Kuppusamy Periannan, Kv1.5 Potassium Channel/*physiology, Lindner Jonathan R, Logan Suzanna, Luli Jordan, Mice, Muscle, Nagane Masaki, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohanyan Vahagn, Oyewumi Moses O, Smooth, Transgenic, Transgenic mice, Vascular/*metabolism, vasodilation, Vasodilation/*physiology, voltage-gated potassium channels, Yin Liya
Antitumor effect of novel gallium compounds and efficacy of nanoparticle-mediated gallium delivery in lung cancer.
Tags: 2012, Antineoplastic Agents/*administration & dosage/chemistry/pharmacokinetics, Biocompatible Materials/administration & dosage/chemistry/pharmacokinetics, Cell Line, Cell Survival/drug effects, Coordination Complexes/*administration & dosage/chemistry/pharmacokinetics, Department of Pharmaceutical Sciences, Drug Carriers/administration & dosage/chemistry, Drug Stability, Endocytosis/drug effects, Gallium/*administration & dosage/chemistry/pharmacokinetics, Hemolysis/drug effects, Humans, Journal of biomedical nanotechnology, Lung Neoplasms/*drug therapy/metabolism, Materials Testing, Membrane Potential, Mitochondrial/drug effects, Nanoparticles/*administration & dosage/chemistry, NEOMED College of Pharmacy, Oyewumi Moses O, Particle Size, Platelet Aggregation/drug effects, Reactive Oxygen Species/metabolism, Transferrin/chemistry/pharmacology, Tumor, Wehrung Daniel
Antitumor efficacy and tolerability of systemically administered gallium acetylacetonate-loaded gelucire-stabilized nanoparticles.
Tags: *Lethal Dose 50, 2013, Adenocarcinoma/*drug therapy/pathology, Animals, Antineoplastic Agents/administration & dosage/pharmacokinetics/toxicity, Bi Lipeng, Cell Line, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Drug Stability, Drug Tolerance, Gallium/*administration & dosage/pharmacokinetics/*toxicity, Geldenhuys Werner J, Humans, Journal of biomedical nanotechnology, Metabolic Clearance Rate, Mice, Nanocapsules/*administration & dosage/chemistry/*toxicity, NEOMED College of Pharmacy, Nude, Organ Specificity, Oyewumi Moses O, Tissue Distribution, Treatment Outcome, Triglycerides/chemistry, Tumor, Wehrung Daniel
Biocompatibility, efficacy and biodistribution of Gelucire-stabilized nanoparticles engineered for docetaxel delivery.
Tags: *Biocompatible Materials, *Nanoparticles, 2012, Animals, Antineoplastic Agents/*administration & dosage/pharmacokinetics/pharmacology, Bi Lipeng, Department of Pharmaceutical Sciences, Docetaxel, Geldenhuys Werner J, Journal of nanoscience and nanotechnology, Macrophage Activation/drug effects, NEOMED College of Pharmacy, Oyewumi Moses O, Platelet Aggregation/drug effects, Rats, Reactive Oxygen Species/metabolism, Taxoids/*administration & dosage/pharmacokinetics/pharmacology, Tissue Distribution, Wehrung Daniel
Therapeutic Delivery of Simvastatin Loaded in PLA-PEG Polymersomes Resulted in Amplification of Anti-inflammatory Effects in Activated Microglia.
Tags: *Drug Delivery Systems, *Inflammation, *Microglia, *neuroprotection, *polymersomes, *simvastatin, 2017, Animals, Anti-Inflammatory Agents/*pharmacology, Department of Pharmaceutical Sciences, Inbred BALB C, Interleukin-6/antagonists & inhibitors/biosynthesis, Lactates/*administration & dosage, Manickavasagam Dharani, Mice, Microglia/*drug effects, NEOMED College of Pharmacy, Nitric Oxide/antagonists & inhibitors/biosynthesis, Novak Kimberly, Oyewumi Moses O, Polyethylene Glycols/*administration & dosage, Simvastatin/*administration & dosage/pharmacology, The AAPS journal, Tumor Necrosis Factor-alpha/antagonists & inhibitors/biosynthesis
Delivery Systems as Vital Tools in Drug Repurposing.
Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses.
Tags: *Microspheres, *Nanoparticles, 2010, Adaptive Immunity, Adjuvants, Animals, Cui Zhengrong, Department of Pharmaceutical Sciences, Expert review of vaccines, Humans, Immunity, Immunologic/*pharmacology, Innate, Kumar Amit, NEOMED College of Pharmacy, Oyewumi Moses O, Particle Size, Vaccines/*immunology
Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells.
Tags: *Cell Movement, *Cell Proliferation, 2016, Animals, Apoptosis, Biomarkers, Carcinoma, Cell Adhesion, Cultured, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Female, GPNMB, Humans, integrin, Lung cancer, Lung Neoplasms/metabolism/*pathology, Manickavasagam Dharani, Membrane Glycoproteins/*metabolism, Mice, Moussa Fouad M, NEOMED College of Medicine, NEOMED College of Pharmacy, Neoplasm Invasiveness, Non-Small-Cell Lung/metabolism/*pathology, Novak Kimberly, NSCLC, Nude, Oncotarget, Oyewumi Moses O, Paulic Nikola, Protein Domains, Safadi Fayez F, Sondag Gregory R, Tumor Cells, Tumor/*metabolism, Wehrung Daniel, Xenograft Model Antitumor Assays
Gelucire-stabilized nanoparticles as a potential DNA delivery system.
Tags: *Gene Transfer Techniques, 2016, Animals, Cationic lipids, Cell Line, Cell Survival/drug effects/physiology, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, DNA/*administration & dosage/chemistry, gene therapy, Hep G2 Cells, Humans, macrophage activation, Macrophages/drug effects/physiology, Mice, Nanoparticles, Nanoparticles/*administration & dosage/chemistry, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Oyewumi Moses O, Pharmaceutical development and technology, Polyethylene Glycols/*administration & dosage/chemistry, Sadana Prabodh, Transfection, Wehrung Daniel
Delivery Systems as Vital Tools in Drug Repurposing.
Internalization of particulate delivery systems by activated microglia influenced the therapeutic efficacy of simvastatin repurposing for neuroinflammation
Nose-to-brain co-delivery of repurposed simvastatin and BDNF synergistically attenuates LPS-induced neuroinflammation
Tags: 2019, And Medicine, Biology, Department of Pharmaceutical Sciences, Drug repurposing, Intranasal delivery, Journal Article, Lin Li, Manickavasagam Dharani, Microglia, Nanomedicine: Nanotechnology, Nanomedicine: Nanotechnology, Biology, And Medicine, Nanoparticles, NEOMED College of Pharmacy, NEOMED College of Pharmacy Student, NEOMED Student Publications, November 2019 Update, Oyewumi Moses O, polymersomes