1
40
3
-
Text
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URL Address
<a href="http://doi.org/10.1152/jn.00472.2014" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/jn.00472.2014</a>
Pages
1819–1830
Issue
6
Volume
113
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A function for binaural integration in auditory grouping and segregation in the inferior colliculus.
Publisher
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Journal of neurophysiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
2015-03
Subject
The topic of the resource
*Auditory Perception; Animals; Auditory; binaural integration; Evoked Potentials; Female; Guinea Pigs; harmonic complex; Inferior Colliculi/cytology/*physiology; inferior colliculus; Male; Neurons/physiology; pitch
Creator
An entity primarily responsible for making the resource
Nakamoto Kyle T; Shackleton Trevor M; Magezi David A; Palmer Alan R
Description
An account of the resource
Responses of neurons to binaural, harmonic complex stimuli in urethane-anesthetized guinea pig inferior colliculus (IC) are reported. To assess the binaural integration of harmonicity cues for sound segregation and grouping, responses were measured to harmonic complexes with different fundamental frequencies presented to each ear. Simultaneously gated harmonic stimuli with fundamental frequencies of 125 Hz and 145 Hz were presented to the left and right ears, respectively, and recordings made from 96 neurons with characteristic frequencies \textgreater2 kHz in the central nucleus of the IC. Of these units, 70 responded continuously throughout the stimulus and were excited by the stimulus at the contralateral ear. The stimulus at the ipsilateral ear excited (EE: 14%; 10/70), inhibited (EI: 33%; 23/70), or had no significant effect (EO: 53%; 37/70), defined by the effect on firing rate. The neurons phase locked to the temporal envelope at each ear to varying degrees depending on signal level. Many of the cells (predominantly EO) were dominated by the response to the contralateral stimulus. Another group (predominantly EI) synchronized to the contralateral stimulus and were suppressed by the ipsilateral stimulus in a phasic manner. A third group synchronized to the stimuli at both ears (predominantly EE). Finally, a group only responded when the waveform peaks from each ear coincided. We conclude that these groups of neurons represent different "streams" of information but exhibit modifications of the response rather than encoding a feature of the stimulus, like pitch.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/jn.00472.2014" target="_blank" rel="noreferrer noopener">10.1152/jn.00472.2014</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Auditory Perception
2015
Animals
Auditory
binaural integration
Evoked Potentials
Female
Guinea Pigs
harmonic complex
Inferior Colliculi/cytology/*physiology
inferior colliculus
Journal of neurophysiology
Magezi David A
Male
Nakamoto Kyle T
Neurons/physiology
Palmer Alan R
pitch
Shackleton Trevor M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1371/journal.pone.0194091" target="_blank" rel="noreferrer noopener">http://doi.org/10.1371/journal.pone.0194091</a>
Pages
e0194091–e0194091
Issue
3
Volume
13
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Communication calls produced by electrical stimulation of four structures in the guinea pig brain.
Publisher
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PloS one
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
1905-07
Subject
The topic of the resource
Female; Male; Animals; Acoustic Stimulation/methods; Auditory Perception/physiology; Brain/*physiology; Electric Stimulation/methods; Guinea Pigs; Neurons/physiology; Animal/physiology; Vocalization
Creator
An entity primarily responsible for making the resource
Green David B; Shackleton Trevor M; Grimsley Jasmine M S; Zobay Oliver; Palmer Alan R; Wallace Mark N
Description
An account of the resource
One of the main central processes affecting the cortical representation of conspecific vocalizations is the collateral output from the extended motor system for call generation. Before starting to study this interaction we sought to compare the characteristics of calls produced by stimulating four different parts of the brain in guinea pigs (Cavia porcellus). By using anaesthetised animals we were able to reposition electrodes without distressing the animals. Trains of 100 electrical pulses were used to stimulate the midbrain periaqueductal grey (PAG), hypothalamus, amygdala, and anterior cingulate cortex (ACC). Each structure produced a similar range of calls, but in significantly different proportions. Two of the spontaneous calls (chirrup and purr) were never produced by electrical stimulation and although we identified versions of chutter, durr and tooth chatter, they differed significantly from our natural call templates. However, we were routinely able to elicit seven other identifiable calls. All seven calls were produced both during the 1.6 s period of stimulation and subsequently in a period which could last for more than a minute. A single stimulation site could produce four or five different calls, but the amygdala was much less likely to produce a scream, whistle or rising whistle than any of the other structures. These three high-frequency calls were more likely to be produced by females than males. There were also differences in the timing of the call production with the amygdala primarily producing calls during the electrical stimulation and the hypothalamus mainly producing calls after the electrical stimulation. For all four structures a significantly higher stimulation current was required in males than females. We conclude that all four structures can be stimulated to produce fictive vocalizations that should be useful in studying the relationship between the vocal motor system and cortical sensory representation.
Identifier
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<a href="http://doi.org/10.1371/journal.pone.0194091" target="_blank" rel="noreferrer noopener">10.1371/journal.pone.0194091</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Acoustic Stimulation/methods
Animal/physiology
Animals
Auditory Perception/physiology
Brain/*physiology
Electric Stimulation/methods
Female
Green David B
Grimsley Jasmine M S
Guinea Pigs
Male
Neurons/physiology
Palmer Alan R
PloS one
Shackleton Trevor M
Vocalization
Wallace Mark N
Zobay Oliver
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/jn.00451.2009" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/jn.00451.2009</a>
Pages
2050–2061
Issue
4
Volume
103
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Responses in the inferior colliculus of the guinea pig to concurrent harmonic series and the effect of inactivation of descending controls.
Publisher
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Journal of neurophysiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2010
2010-04
Subject
The topic of the resource
*Acoustic Stimulation; Action Potentials/physiology; Animal; Animals; Auditory Cortex/*physiology; Auditory Pathways/*physiology; Female; Guinea Pigs; Inferior Colliculi/*physiology; Male; Models; Pitch Perception/physiology
Creator
An entity primarily responsible for making the resource
Nakamoto Kyle T; Shackleton Trevor M; Palmer Alan R
Description
An account of the resource
One of the fundamental questions of auditory research is how sounds are segregated because, in natural environments, multiple sounds tend to occur at the same time. Concurrent sounds, such as two talkers, physically add together and arrive at the ear as a single input sound wave. The auditory system easily segregates this input into a coherent perception of each of the multiple sources. A common feature of speech and communication calls is their harmonic structure and in this report we used two harmonic complexes to study the role of the corticofugal pathway in the processing of concurrent sounds. We demonstrate that, in the inferior colliculus (IC) of the anesthetized guinea pig, deactivation of the auditory cortex altered the temporal and/or the spike response to the concurrent, monaural harmonic complexes. More specifically, deactivating the auditory cortex altered the representation of the relative level of the complexes. This suggests that the auditory cortex modulates the representation of the level of two harmonic complexes in the IC. Since sound level is a cue used in the segregation of auditory input, the corticofugal pathway may play a role in this segregation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/jn.00451.2009" target="_blank" rel="noreferrer noopener">10.1152/jn.00451.2009</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Acoustic Stimulation
2010
Action Potentials/physiology
Animal
Animals
Auditory Cortex/*physiology
Auditory Pathways/*physiology
Female
Guinea Pigs
Inferior Colliculi/*physiology
Journal of neurophysiology
Male
Models
Nakamoto Kyle T
Palmer Alan R
Pitch Perception/physiology
Shackleton Trevor M