1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1038/gt.2012.32" target="_blank" rel="noreferrer noopener">http://doi.org/10.1038/gt.2012.32</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
583-587
Issue
6
Volume
19
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
SDF-1 in myocardial repair
Publisher
An entity responsible for making the resource available
Gene Therapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-06
Subject
The topic of the resource
acute myocordial infarction; Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology; chemokines; gene-therapy; Genetics & Heredity; Heart failure; infarction; ischemic cardiomyopathy; mesenchymal stem-cells; pilot trial; regeneration; Regenerative medicine; Research & Experimental Medicine; stem-cells
Creator
An entity primarily responsible for making the resource
Penn M S; Pastore J; Miller T; Aras R
Description
An account of the resource
Stem cell therapy for the prevention and treatment of cardiac dysfunction holds significant promise for patients with ischemic heart disease. Excitingly early clinical studies have demonstrated safety and some clinical feasibility, while at the same time studies in the laboratory have investigated mechanisms of action and strategies to optimize the effects of regenerative cardiac therapies. One of the key pathways that has been demonstrated critical in stem cell-based cardiac repair is (stromal cell-derived factor-1) SDF-1:CXCR4. SDF-1:CXCR4 has been shown to affect stem cell homing, cardiac myocyte survival and ventricular remodeling in animal studies of acute myocardial infarction and chronic heart failure. Recently released clinical data suggest that SDF-1 alone is sufficient to induce cardiac repair. Most importantly, studies like those on the SDF-1:CXCR4 axis have suggested mechanisms critical for cardiac regenerative therapies that if clinical investigators continue to ignore will result in poorly designed studies that will continue to yield negative results. Gene Therapy (2012) 19, 583-587; doi:10.1038/gt.2012.32
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1038/gt.2012.32" target="_blank" rel="noreferrer noopener">10.1038/gt.2012.32</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2012
acute myocordial infarction
Aras R
Biochemistry & Molecular Biology
Biotechnology & Applied Microbiology
chemokines
gene therapy
gene-therapy
Genetics & Heredity
Heart failure
Infarction
ischemic cardiomyopathy
Journal Article
mesenchymal stem-cells
Miller T
Pastore J
Penn M S
pilot trial
Regeneration
Regenerative Medicine
Research & Experimental Medicine
stem-cells
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
S142-S143
Volume
22
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Cornoary Sinus Delivery of SDF-1 Plasmid Improves Cardiac Function in a Porcine Model of Heart Failure
Publisher
An entity responsible for making the resource available
Molecular Therapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2014
2014-05
Subject
The topic of the resource
Biotechnology & Applied Microbiology; Experimental Medicine; Genetics & Heredity; Research &
Creator
An entity primarily responsible for making the resource
Woda J M; Fisher S J; Pastore J; Aras R; Patel A; Penn M S
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2014
Aras R
Biotechnology & Applied Microbiology
Department of Internal Medicine
Experimental Medicine
Fisher S J
Genetics & Heredity
Journal Article
Molecular Therapy
NEOMED College of Medicine
Pastore J
Patel A
Penn M S
Research &
Woda J M