Inhibition Of Apoptosis In Human Retinal Pigment Epithelial Cells Treated With Benzo(e)pyrene, A Toxic Component Of Cigarette Smoke
alzheimers-disease; dna-damage; experimental glaucoma; genistein; macular degeneration; memantine treatment; mitochondrial dysfunction; Ophthalmology; oxidative stress; protects; resveratrol
Mansoor S; Gupta N; Patil A J; Estrago-Franco M F; Ramirez C; Migon R; Sapkal A; Kuppermann B D; Kenney M C
Investigative Ophthalmology & Visual Science
2010
2010-05
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1167/iovs.09-4121" target="_blank" rel="noreferrer noopener">10.1167/iovs.09-4121</a>
Copper Deposition In A Variant Of Multiple Myeloma: Pathologic Changes In The Cornea And The Lens Capsule
central defect; copper deposition; deposition; Descemet membrane; descemets membrane; hypercupremia; immunoglobulin; leukomas; monoclonal gammopathy; multiple myeloma; ocular; Ophthalmology; true exfoliation; wilsons-disease
Edward D P; Patil A J; Sugar J; Parikh M
Cornea
2011
2011-03
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1097/ICO.0b013e3181ee67fd" target="_blank" rel="noreferrer noopener">10.1097/ICO.0b013e3181ee67fd</a>
Bimatoprost - a review
acid; aqueous-humor; bimatoprost; clinical-trial; cost-effectiveness; elevated intraocular-pressure; fixed combination; free; glaucoma; human eyes; Intraocular pressure; ocular hypertension; open-angle glaucoma; Pharmacology & Pharmacy; prostaglandin; prostaglandin-ethanolamides; prostamide; prostamides
Bimatoprost is a synthetic prostamide analog that is efficacious in the treatment of open-angle glaucoma, ocular hypertension and other forms of glaucoma. it reduces intraocular pressure (IOP) by increasing uveoscleral and trabecular outflow. When used as a 0.03% topical preparation once daily, it demonstrates sustained lowering of IOP of 7 - 8 mmHg over a 24-h period. The drug has been found to be more effective than timolol. In some studies it has shown greater ability to lower IOP when compared with other prostaglandin analogs; whereas in others all three clinically used prostaglandin analogs were found to be equally effective. it shows good IOP reduction when used in combination with other glaucoma medications. A common side effect includes mild conjunctival hyperemia, which is generally reversible. Other side effects include periorbital pigmentation, discomfort, ocular surface hyperemia and skin changes. Pharmacoeconomic data indicate that bimatoprost is cost effective in the treatment of open-angle glaucoma.
Patil A J; Vajaranant T S; Edward D P
Expert Opinion on Pharmacotherapy
2009
2009-11
Journal Article
<a href="http://doi.org/10.1517/14656560903292649" target="_blank" rel="noreferrer noopener">10.1517/14656560903292649</a>