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Text
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Pages
2221–2227
Issue
11
Volume
25
Dublin Core
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Title
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Recognition of hypertrophic osteoarthropathy in skeletal remains.
Publisher
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The Journal of rheumatology
Date
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1998
1998-11
Subject
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Humans; Reproducibility of Results; Cadaver; Bone and Bones/*pathology; Diaphyses/pathology; Periosteum/pathology; Syphilis/pathology; Yaws/pathology; Osteoarthropathy; Primary Hypertrophic/*pathology
Creator
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Rothschild B M; Rothschild C
Description
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OBJECTIVE: To characterize hypertrophic osteoarthropathy (HOA) in skeletons to allow its recognition in the archeologic record. METHODS: Individuals diagnosed in life with diseases known to cause HOA were examined from the Hamman-Todd, Grant, and Terry human skeletal collections. The latter consist of 5142 individuals who died in the early part of this century. A "control" group was obtained by examination of 100 (consecutive, exclusive of HOA related disorders) additional individuals from the Terry Collection, which were accompanied by diagnoses not known to be associated with HOA. Sixty individuals documented with skeletal evidence of syphilis (from the Hamman-Todd Collection) and 73 individuals documented as having skeletal evidence of yaws (from the Ward Site, 4300 ybp) were examined as comparison treponemal disease-derived, periosteal reaction-afflicted populations. RESULTS: In total, 319 individuals were identified with HOA. HOA was recognized as a disorder of distal diaphyseal or diffuse periosteal reaction. Proximally-limited disease virtually eliminates the diagnosis. CONCLUSION: HOA is recognizable as a population phenomenon suggestive, when found in the archeologic record, of underlying chronic pulmonary disease.
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1998
Bone and Bones/*pathology
Cadaver
Diaphyses/pathology
Humans
Osteoarthropathy
Periosteum/pathology
Primary Hypertrophic/*pathology
Reproducibility of Results
Rothschild B M
Rothschild C
Syphilis/pathology
The Journal of rheumatology
Yaws/pathology