Browse Items (30 total)
- Tags: Phosphorylation
PKCalpha mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.
Tags: 2011, Acetylcholine/*pharmacology, Adapala Ravi K, American journal of physiology. Heart and circulatory physiology, Animals, Bratz Ian N, Calcium Signaling/*drug effects, Carbazoles/pharmacology, Cells, Cultured, Department of Integrative Medical Sciences, Endothelial Cells/*drug effects/enzymology, Enzyme Activation, Inbred C57BL, Knockout, Male, Mesenteric Arteries/drug effects/enzymology, Meszaros J Gary, Mice, Mutation, NEOMED College of Medicine, Nitric Oxide Synthase Type III/metabolism, Phosphorylation, Protein Kinase C-alpha/genetics/*metabolism, Protein Kinase Inhibitors/pharmacology, Suzuki Makoto, Talasila Phani K, Tetradecanoylphorbol Acetate/pharmacology, Thodeti Charles K, Time Factors, Transfection, TRPV Cation Channels/*agonists/deficiency/genetics/metabolism, Vasodilation/*drug effects, Vasodilator Agents/*pharmacology, Zhang David X
Neurokinin-1 receptor resensitization precedes receptor recycling.
Tags: 2005, Adenosine Triphosphate/pharmacology, Animals, Bennett V J, Binding, Calcium/metabolism, CHO Cells, Competitive, Cricetinae, Guanylyl Imidodiphosphate/pharmacology, Neurokinin-1/*metabolism, Perrine S A, Phosphorylation, Rats, Receptors, Simmons M A, Substance P/metabolism, The Journal of pharmacology and experimental therapeutics
Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis.
Tags: 2013, Acute/chemically induced, Animals, Carcinoma, Cell Movement, Cell Proliferation/drug effects, Chen Wei-Dong, Diethylnitrosamine, Forman Barry M, G-Protein-Coupled/*deficiency, Hepatocellular/*chemically induced, Hepatology (Baltimore, Md.), Huang Wendong, Humans, Liver Failure, Liver Neoplasms/*chemically induced, Mice, Phosphorylation, Receptors, STAT3 Transcription Factor/physiology, Tumor Suppressor Proteins/*physiology, Wang Yan-Dong, Yu Donna
Low-density lipoprotein receptor-related protein mediates in PC12 cell cultures the inhibition of nerve growth factor-promoted neurite outgrowth by pregnancy zone protein and alpha(2)-macroglobulin
Tags: 2002, alpha-2-macroglobulin, alpha-macroglobulin, alpha-macroglobulins, amyloid precursor protein, Binding, Chiabrando G A, cytosolic adapter, gene-expression, Journal Article or Conference Abstract Publication, Journal of neuroscience research, Koo P H, low-density lipoprotein receptor-related protein, lrp, neurological diseases, Neurosciences & Neurology, Phosphorylation, rat alpha-1-macroglobulin, Receptors, Sanchez M C, Signal Transduction, Skornicka E L, trk, Trk regulation
Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer's Disease.
Tags: *Alzheimer Disease/complications/genetics/pathology, *Alzheimer's disease, *bone density, *microtubule-associated protein, *serotonin, *tau proteins, *tauopathies, 2017, Age Factors, Alzheimer's disease, Alzheimer's Disease – Complications, Alzheimer's Disease – Pathology, Animal, Animal Studies, Animals, Biological, Body Composition, Body Composition/genetics, Body Weight, Body Weight/genetics, Bone Density – Physiology, Bone Density/*physiology, Bone Diseases – Etiology, Bone Diseases/*etiology, Brain Stem – Pathology, Dengler-Crish Christine M, Department of Pharmaceutical Sciences, Disease Models, Dorsal Raphe Nucleus/*pathology, Female, Inbred C57BL, Journal of Alzheimer's disease : JAD, Male, Mice, Models, NEOMED College of Pharmacy, Nerve Tissue Proteins, Nerve Tissue Proteins – Metabolism, Neurodegenerative Diseases, Neurodegenerative Diseases – Complications, Neurons – Metabolism, Neurons – Pathology, Neurons/metabolism/pathology, Oxidoreductases – Metabolism, Phosphorylation, Serotonin – Metabolism, Serotonin/*metabolism, Smith Matthew A, tau Proteins/*genetics/metabolism, Tauopathies/complications/genetics, Transgenic, Tryptophan Hydroxylase/metabolism, Wilson Gina N
Parkinson's disease biomarker: a patent evaluation of WO2013153386.
Tags: 2014, Abdelmagid Samir M, Autophagy, Biomarkers/metabolism, clinical testing, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Disease Progression, Dopaminergic Neurons/pathology, Expert opinion on therapeutic patents, Gallegos Patrick J, Geldenhuys Werner J, Humans, Mitochondria/pathology, mitochondrial membrane potential, mitophagy, NEOMED College of Medicine, NEOMED College of Pharmacy, Parkinson Disease/*diagnosis/physiopathology, Patents as Topic, Phosphorylation, Protein Kinases/*metabolism, Safadi Fayez F, Ubiquitin-Protein Ligases/*metabolism
Inhibition of phosphorylation of TrkB and TrkC and their signal transduction by alpha2-macroglobulin.
Tags: *Mitogen-Activated Protein Kinases, 1998, 3T3 Cells/chemistry/cytology/enzymology, alpha-Macroglobulins/*pharmacology, Animals, Antineoplastic Agents/pharmacology, Brain-Derived Neurotrophic Factor/pharmacology, Calcium-Calmodulin-Dependent Protein Kinases/metabolism, Cell Differentiation/drug effects, Ciliary Neurotrophic Factor, Cultured/chemistry/cytology/enzymology, Hu Y Q, Humans, Isoenzymes/metabolism, Journal of neurochemistry, Koo P H, Mice, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3, Nerve Growth Factor/*metabolism, Nerve Growth Factors/pharmacology, Neuroblastoma, Neuroprotective Agents/*metabolism, Neurotrophin 3, Phospholipase C gamma, Phosphorylation, Receptor, Receptor Protein-Tyrosine Kinases/*metabolism, Receptors, Serotonin/metabolism, Signal Transduction/drug effects/*physiology, Tretinoin/pharmacology, trkC, Tumor Cells, Type C Phospholipases/metabolism
Angiotensin Type I Receptor Blockade In Conjunction With Enhanced Akt Activation Restores Coronary Collateral Growth In The Metabolic Syndrome
Tags: 2011, American Journal of Physiology-Heart and Circulatory Physiology, Bailey E, Cardiovascular System & Cardiology, coronary artery occlusion, DeLucia A L, Dodd T, endothelial-cells, inhibition, ischemia-induced angiogenesis, Jadhav R, Jo H J, Journal Article or Conference Abstract Publication, Kinase, Madison R, mediated angiogenesis, nitric-oxide synthase, pathway, Phosphorylation, Physiology, Potter B, rat, Rocic P, Russell J C, Smith E, smooth-muscle-cells, transient, Walsh K
Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.
Tags: 2005, American journal of physiology. Gastrointestinal and liver physiology, Cell Line, Chenodeoxycholic Acid/pharmacology, Chiang John Y L, Chromosome Mapping, Department of Integrative Medical Sciences, DNA-Binding Proteins/genetics/metabolism, Enzyme Inhibitors/pharmacology, Gene Expression Regulation/*drug effects, Genetic/drug effects, Genetic/physiology, Hepatocyte Nuclear Factor 4, Hepatocytes/metabolism, Humans, Interleukin-1/*pharmacology, Jahan Asmeen, MAP Kinase Signaling System/drug effects/physiology, Messenger/antagonists & inhibitors, Mitogen-Activated Protein Kinase 8/metabolism, Mitogen-Activated Protein Kinases/antagonists & inhibitors, NEOMED College of Medicine, Phosphoproteins/genetics/metabolism, Phosphorylation, Promoter Regions, Response Elements/genetics, RNA, Steroid 12-alpha-Hydroxylase/antagonists & inhibitors/*genetics, Transcription, Transcription Factors/genetics/metabolism
Novel noncanonical regulation of soluble VEGF/VEGFR2 signaling by mechanosensitive ion channel TRPV4.
Tags: 2019, Adapala Ravi K, angiogenesis, Cappelli Holly C, Chilian William M, Department of Integrative Medical Sciences, endothelial cell, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Kanugula Anantha K, Meszaros J Gary, Midha Priya, NEOMED College of Medicine, Paruchuri Sailaja, Phosphorylation, Thodeti Charles K
Monoamine-activated alpha 2-macroglobulin binds trk receptor and inhibits nerve growth factor-stimulated trk phosphorylation and signal transduction.
Tags: 1994, Adrenal Gland Neoplasms, alpha-Macroglobulins/isolation & purification/*metabolism/pharmacology, Animals, ErbB Receptors/isolation & purification/metabolism, Fibrinolysin/metabolism, Humans, Koo P H, Male, Mice, Mitogen-Activated Protein Kinase 1, Nerve Growth Factor/drug effects/isolation & purification/*metabolism, Nerve Growth Factors/*pharmacology, Neurites/drug effects/*physiology, PC12 Cells, Pheochromocytoma, Phosphorylation, Platelet-Derived Growth Factor/isolation & purification/metabolism, Protein-Serine-Threonine Kinases/metabolism, Protein-Tyrosine Kinases/metabolism, Proto-Oncogene Proteins/drug effects/isolation & purification/*metabolism, Qiu W S, Receptor, Receptor Protein-Tyrosine Kinases/drug effects/isolation & purification/*metabolism, Receptors, Serotonin/*metabolism/pharmacology, Signal Transduction/drug effects/*physiology, The Journal of biological chemistry, trkA
Lung fluid absorption is induced in preterm guinea pigs ventilated with low tidal volumes.
Tags: *Premature Birth, *Tidal Volume, 2011, Absorption, Albumins/administration & dosage/*metabolism, Animals, Artificial/adverse effects/*methods, Beard LaMonta L, Enzyme Activation, Epinephrine/blood, Epithelial Sodium Channels/metabolism, Experimental lung research, Extracellular Signal-Regulated MAP Kinases/metabolism, Extravascular Lung Water/*metabolism, Fetal Organ Maturity, Folkesson Hans G, Gestational Age, Guinea Pigs, Hydrocortisone/blood, Intratracheal, Intubation, Koshy Shyny, Kuzenko Stephanie R, Li Tianbo, Lung/embryology/*metabolism/physiopathology, MAP Kinase Kinase Kinases/metabolism, Newborn, Permeability, Phosphorylation, Respiration, Sodium-Potassium-Exchanging ATPase/metabolism, Time Factors, Ventilator-Induced Lung Injury/metabolism/physiopathology/*prevention & control
Generation and characterization of ATP analog-specific protein kinase Cdelta.
Tags: 2015, Adenosine Triphosphate/*analogs & derivatives/*chemistry, Amino Acid, Amino Acid Sequence, Animals, ATP, Catalysis, Cercopithecus aethiops, Chemical Biology, Chou Wen-Hai, COS Cells, Geldenhuys Werner J, Glutamine/chemistry, Han Xiqian, Humans, Inbred C57BL, Kumar Varun, Leucine/chemistry, Lysine/chemistry, Messing Robert O, Mice, Molecular Sequence Data, Neutrophils/metabolism, Phenylalanine/chemistry, Phosphorylation, Protein Binding, Protein Kinase C (PKC), Protein Kinase C-delta/*metabolism, Protein Phosphorylation, Purines/chemistry, Sequence Homology, Signal Transduction, stroke, Substrate Specificity, Superoxides/chemistry, The Journal of biological chemistry, Transgenic, Wang Dan, Weng Yi-Chinn
Ampk-dependent Repression Of Hepatic Gluconeogenesis Via Disruption Of Creb Center Dot Crtc2 Complex By Orphan Nuclear Receptor Small Heterodimer Partner
Tags: 2010, activated protein-kinase, binding-protein, Biochemistry & Molecular Biology, Chanda D, Chiang J Y L, Choi H S, creb coactivator crtc2, gene-expression, insulin, Journal Article or Conference Abstract Publication, Journal of Biological Chemistry, Kim D K, Kim Y D, Kim Y H, Koo S H, Lee C H, Lee J M, Lee M W, metformin, Noh J R, Phosphorylation, Ryu D, Seo W Y, SHP, Song K H, torc2, transcriptional activity
Rat alpha(2)-macroglobulin inhibits NGF-promoted neurite outgrowth, TrK phosphorylation, and gene expression of pheochromocytoma PC12 cells.
Tags: 1999, Adrenal Gland Neoplasms/metabolism, alpha-Macroglobulins/*pharmacology, Animals, Gene Expression Regulation, Journal of neuroscience research, Koo P H, Lee P G, Neoplastic/*drug effects, Nerve Growth Factors/*antagonists & inhibitors, Neurites/*drug effects, PC12 Cells, Pheochromocytoma/metabolism, Phosphorylation, Proto-Oncogene Proteins c-jun/genetics, Rats, Receptor, Sprague-Dawley, trkA/*metabolism
Curcumin Differentially Regulates Endoplasmic Reticulum Stress through Transcriptional Corepressor SMILE (Small Heterodimer Partner-interacting Leucine Zipper Protein)-mediated Inhibition of CREBH (cAMP Responsive Element-binding Protein H)
Tags: 2011, atf6, Back S H, Biochemistry & Molecular Biology, Cells, Chanda D, Chiang J Y L, Choi H S, creb/atf-family, er stress, gene-expression, hepatic gluconeogenesis, Journal Article or Conference Abstract Publication, Journal of Biological Chemistry, Kim D K, Kinase, Koo S H, Li T G, lkb1, Misra J, Phosphorylation, zhangfei
Characterization of vascular endothelial growth factor (VEGF) in the uterine cervix over pregnancy: effects of denervation and implications for cervical ripening.
Tags: 2004, Animal/*metabolism, Animals, Cervical Ripening/*metabolism, Cervix Uteri/blood supply/innervation/*metabolism, Denervation, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme-Linked Immunosorbent Assay, Female, Hattori Y, Immunohistochemistry, Jesmin S, Microcirculation, Mowa C N, NEOMED College of Medicine, Nitric Oxide Synthase Type III, Nitric Oxide Synthase/biosynthesis, Papka R, Phosphorylation, Pregnancy, Protein Isoforms/biosynthesis/metabolism, Protein-Serine-Threonine Kinases/biosynthesis, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins/biosynthesis, Rats, Reverse Transcriptase Polymerase Chain Reaction, Sakuma I, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Togashi H, Usip S, Vascular Endothelial Growth Factor A/biosynthesis/*metabolism, Vascular Endothelial Growth Factor Receptor-2/biosynthesis, Wistar, Yoshioka M
Members of the novel UBASH3/STS/TULA family of cellular regulators suppress
Tags: 2014, Animals, Antigen, Carpino Nick, Colitis/*immunology, Department of Anatomy & Neurobiology, Ganea Doina, Humans, Immunology and cell biology, Ivanova Elitza, Knockout, Kunapuli Satya P, Liverani Elisabetta, Mice, NEOMED College of Medicine, Newman Tiffanny N, Phosphorylation, Protein Tyrosine Phosphatases/genetics/*physiology, Receptors, Russo Gian L, Safadi Fayez, T-Cell/genetics/*physiology, T-Lymphocytes/*immunology, Tsygankov Alexander Y, ZAP-70 Protein-Tyrosine Kinase/metabolism
Angiotensin II-induced extracellular signal-regulated kinase 1/2 activation is mediated by protein kinase Cdelta and intracellular calcium in adult rat cardiac fibroblasts.
Tags: 2008, Acetophenones/pharmacology, Angiotensin II/*physiology, Animals, Benzopyrans/pharmacology, Calcium/*metabolism, Cell Proliferation, Cells, Cultured, Department of Integrative Medical Sciences, Enzyme Activation, ErbB Receptors/metabolism, Fibroblasts/*metabolism, Hypertension (Dallas, Tex. : 1979), Male, Meszaros J Gary, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, Myocardium/*cytology/metabolism, Naugle Jennifer E, NEOMED College of Medicine, Olson Erik R, Phorbol Esters/pharmacology, Phosphorylation, Protein Kinase C-delta/genetics/*metabolism, Rats, Shamhart Patricia E, Signal Transduction/physiology, Sprague-Dawley
Salvianolate reduces murine myocardial ischemia and reperfusion injury via ERK1/2 signaling pathways in vivo.
Tags: *MAP Kinase Signaling System/drug effects, 2017, Animal Studies, Animals, Blotting, Cardiotonic Agents/pharmacology/therapeutic use, Chinese journal of integrative medicine, Chinese medicine, Descriptive Statistics, extracellular signal-regulated kinase 1/2, Flavonoids/pharmacology, Guo Liheng, Heart Ventricle, Heart Ventricles/drug effects/pathology, Huang Dong-Hui, Huang Hai-Ding, Huang Xin, In Vivo Studies, Inbred C57BL, ischemia and reperfusion injury, Left, Male, Mice, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, Molecular Structure, Myocardial Ischemia – Drug Therapy, Myocardial Reperfusion Injury – Drug Therapy, Myocardial Reperfusion Injury/*drug therapy/enzymology/pathology, Organ Size/drug effects, P-Value, Phosphorylation, Phosphorylation/drug effects, Plant Extracts – Administration and Dosage, Plant Extracts/chemistry/pharmacology/*therapeutic use, protein kinase B, Protein Kinase Inhibitors – Administration and Dosage, Protein Kinase Inhibitors/pharmacology, Protein Kinases – Analysis, Protein Kinases – Drug Effects, Qi Jianyong, salvianolate, Signal Transduction, Staining and Labeling, Wang Lei, Western, Wu Jiashin, Yu Juan, Zhang Minzhou, Zhou Miao
Mechanisms of Chinese Medicine Xinmailong's protection against heart failure in pressure-overloaded mice and cultured cardiomyocytes.
Tags: 2017, Animal, Animals, Cardiac/cytology/*drug effects/metabolism, Cell Nucleus/metabolism, Cell Survival/drug effects, Cells, Chen Renshan, Chen Yanfen, Chinese Herbal/*administration & dosage/pharmacology, Constriction, Cultured, Disease Models, Drugs, Echocardiography, GABA Plasma Membrane Transport Proteins/*metabolism, Gene Expression Regulation/drug effects, Glycogen Synthase Kinase 3 beta/metabolism, Gu Weiwang, Heart Failure/etiology/metabolism/physiopathology/*prevention & control, Humans, Liu Qin, Lu Jun, MAP Kinase Signaling System/drug effects, Mice, Myocytes, Pathologic, Phosphorylation, Proto-Oncogene Proteins c-akt/metabolism, Qi Jianyong, Rats, Scientific reports, Tan Yafang, Wu Jiashin, Xu Wen, Yu Juan, Zhang Minzhou
alpha(2)-Macroglobulin modulates the immunoregulatory function of the lipocalin placental protein 14
Tags: 2000, alpha-2-macroglobulin, alpha-macroglobulin, Binding, Biochemical Journal, Biochemistry & Molecular Biology, factor-beta, Glycodelin, Human, immunosuppressive, inhibition, Journal Article, Koo P H, nerve growth-factor, Phosphorylation, phytohemagglutinin, pregnancy proteins, Proteins, Rachmilewitz J, Receptor, Riely G J, serum carrier, serum transport, signal-transduction, Tykocinski M L
Redox-dependent coronary metabolic dilation.
Tags: *Paracrine Communication, *Vasodilation/drug effects, 2007, Acetylcysteine/pharmacology, American journal of physiology. Heart and circulatory physiology, Animals, Antioxidants/pharmacology, Cardiac/drug effects/*metabolism, Chilian William M, Conditioned/metabolism, Coronary Vessels/drug effects/enzymology/*metabolism, Culture Media, Department of Integrative Medical Sciences, Dick Gregory M, Dithiothreitol/pharmacology, Enzyme Activation, Fluorescence, Hydrogen Peroxide/metabolism, Imidazoles/pharmacology, In Vitro Techniques, Kiyooka Takahiko, Microscopy, Myocytes, NEOMED College of Medicine, Nitroprusside/pharmacology, Oxidation-Reduction, p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism, Park Yoonjung, Phosphorylation, Protein Kinase Inhibitors/pharmacology, Pyridines/pharmacology, Rats, Reactive Oxygen Species/*metabolism, Reducing Agents/pharmacology, Rocic Petra, Rogers Paul A, Saitoh Shu-ichi, Sulfhydryl Compounds/*metabolism, Swafford Albert, Vasodilator Agents/pharmacology, Viswanathan Chandrasekar, Wistar, Zhang Cuihua
Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells.
Tags: 2002, Angiotensin II/*metabolism, Animals, Arachidonic Acid/metabolism, Arachidonic Acids/pharmacology, Archives of biochemistry and biophysics, Blotting, Cells, Chromones/pharmacology, Cultured, Enzyme Inhibitors/pharmacology, Flavonoids/pharmacology, Freeman Ernest J, Group IV Phospholipases A2, Male, Mitogen-Activated Protein Kinases/metabolism, Morpholines/pharmacology, Muscle, Phosphatidylinositol 3-Kinases/*physiology, Phospholipases A/*metabolism, Phospholipases A2, Phosphorylation, Rats, Silfani Tonous N, Smooth, Sprague-Dawley, Vascular/drug effects/*growth & development, Western
Changes of the responses of single sympathetic ganglionic neurones to substance P following desensitization
Tags: 2001, adenylate-cyclase, Binding, Cells, Desensitization, G protein, inhibition, Journal Article, Journal of Autonomic Pharmacology, k+ current, kinase-c, M current, muscarine, Neurosciences & Neurology, Pharmacology & Pharmacy, Phosphorylation, protein alpha-subunits, Receptor, rgs proteins, Simmons M A, SUBSTANCE P
Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.
Tags: *Gluconeogenesis, 2006, 8-Bromo Cyclic Adenosine Monophosphate/*pharmacology, Adolescent, Bile Acids and Salts/*biosynthesis, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Chromatin/metabolism, Cultured, Cyclic AMP-Dependent Protein Kinases/physiology, Department of Integrative Medical Sciences, Enzymologic/*drug effects, Female, Gene Expression Regulation, Genetic/drug effects, Glucagon/*pharmacology, Hepatocyte Nuclear Factor 4/genetics/metabolism, Hepatocytes/*enzymology, Hepatology (Baltimore, Md.), Humans, Male, Messenger/analysis, Middle Aged, NEOMED College of Medicine, Organ Specificity, Phosphorylation, RNA, Song Kwang-Hoon, Transcription
The antiviral xanthate compound D609 inhibits herpes simplex virus type 1 replication and protein phosphorylation
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Tags: 1994, Acyclovir/pharmacology, Amino Acid Sequence, Antiviral Agents/metabolism/*pharmacology, Base Sequence, Binding Sites, Bromodeoxyuridine/*analogs & derivatives/metabolism/pharmacology, Deoxyuridine/analogs & derivatives/pharmacology, DNA, Docherty J J, Drug Resistance, Herpesvirus 1, Human/drug effects/*enzymology/genetics, Humans, Kinetics, Microbial, Molecular Sequence Data, Phosphonoacetic Acid/pharmacology, Phosphorylation, Point Mutation/genetics, Sequence Analysis, The Journal of general virology, Thymidine Kinase/genetics/metabolism, Thymidine/metabolism, Vidarabine/pharmacology, Wilber B A
Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma.
Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.
Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko