1
40
2
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1006/bbrc.1995.1885" target="_blank" rel="noreferrer noopener">http://doi.org/10.1006/bbrc.1995.1885</a>
Pages
819–825
Issue
3
Volume
211
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Binding of sequence-specific proteins to the 3'-untranslated region of vasoactive intestinal peptide mRNA.
Publisher
An entity responsible for making the resource available
Biochemical and biophysical research communications
Date
A point or period of time associated with an event in the lifecycle of the resource
1995
1995-06
Subject
The topic of the resource
Animals; Anterior/*metabolism; Base Sequence; Binding; Competitive; Cytoplasm/chemistry; Gene Expression Regulation; Genomic Library; Male; Messenger/*metabolism; Molecular Sequence Data; Pituitary Gland; Post-Transcriptional; Protein Binding; Proto-Oncogene Proteins c-fos/genetics; Rats; RNA; RNA Processing; RNA-Binding Proteins/*metabolism; RNA/metabolism; Sprague-Dawley; Subcellular Fractions; Tissue Distribution; Vasoactive Intestinal Peptide/*genetics
Creator
An entity primarily responsible for making the resource
Wolford J K; Signs S A
Description
An account of the resource
Multimeric AUUUA elements in an AU-rich 3'-untranslated region (3'-UTR) have been shown to confer message instability to numerous ephemeral transcripts through the formation of RNA-protein complexes. We show here that the 3'-UTR of VIP mRNA, which contains 3 AUUUA motifs in an AU-rich context, forms specific complexes with cytoplasmic proteins in a concentration-dependent, tissue-specific manner. We also demonstrate that an AU-rich segment of c-fos mRNA can successfully compete with VIP mRNA for binding with cytoplasmic proteins. These studies provide the first evidence for a mechanism by which VIP is post-transcriptionally regulated through specific sequences in its 3'-UTR.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1006/bbrc.1995.1885" target="_blank" rel="noreferrer noopener">10.1006/bbrc.1995.1885</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1995
Animals
Anterior/*metabolism
Base Sequence
Binding
Biochemical and biophysical research communications
Competitive
Cytoplasm/chemistry
Gene Expression Regulation
Genomic Library
Male
Messenger/*metabolism
Molecular Sequence Data
Pituitary Gland
Post-Transcriptional
Protein Binding
Proto-Oncogene Proteins c-fos/genetics
Rats
RNA
RNA Processing
RNA-Binding Proteins/*metabolism
RNA/metabolism
Signs S A
Sprague-Dawley
Subcellular Fractions
Tissue Distribution
Vasoactive Intestinal Peptide/*genetics
Wolford J K
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0006-291x(89)92092-5" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0006-291x(89)92092-5</a>
Pages
18–24
Issue
1
Volume
163
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The characterization of three types of partially processed mRNA and two pseudogenes for human liver cytochrome b5.
Publisher
An entity responsible for making the resource available
Biochemical and biophysical research communications
Date
A point or period of time associated with an event in the lifecycle of the resource
1989
1989-08
Subject
The topic of the resource
Humans; Amino Acid Sequence; Base Sequence; Molecular Sequence Data; Liver/*physiology; DNA/genetics; Cytochrome b Group/*genetics; Cytochromes b5; Pseudogenes; Cloning; Molecular; Post-Transcriptional; RNA Processing
Creator
An entity primarily responsible for making the resource
Yoo M; Steggles A W
Description
An account of the resource
We have isolated cDNA clones corresponding to partially processed human liver cytochrome b5 mRNAs. All the clones contained poly(A) sequences, and one clone had a shorter 3' non-translated sequence, indicating the use of an alternative poly(A) addition signal. In addition, all the clones contained the coding information for amino acids 87-134; however, there were two types of intron junction adjacent to the coding sequence. Detailed analysis of the Type I clones showed that the Type II intron sequence was contained within the Type I sequence, but approximately 1000 bp 5' of the Type I intron-exon junction showed alternative splicing within this intron. In addition, we have isolated two pseudogenes which lack introns, suggesting the retroviral insertion of human liver cytochrome b5 mRNA sequences into the human genome.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0006-291x(89)92092-5" target="_blank" rel="noreferrer noopener">10.1016/0006-291x(89)92092-5</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1989
Amino Acid Sequence
Base Sequence
Biochemical and biophysical research communications
Cloning
Cytochrome b Group/*genetics
Cytochromes b5
DNA/genetics
Humans
Liver/*physiology
Molecular
Molecular Sequence Data
Post-Transcriptional
Pseudogenes
RNA Processing
Steggles A W
Yoo M