1
40
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/jts.21731" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jts.21731</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
543-550
Issue
5
Volume
25
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pharmacological Secondary Prevention Of Ptsd In Youth: Challenges And Opportunities For Advancement
Publisher
An entity responsible for making the resource available
Journal of Traumatic Stress
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-10
Subject
The topic of the resource
children; conditioned fear; cortisol; memory; morphine; pediatric injury patients; posttraumatic-stress-disorder; propranolol; Psychiatry; Psychology; stress; symptoms; traumatic
Creator
An entity primarily responsible for making the resource
Maccani M A; Delahanty D L; Nugent N R; Berkowitz S J
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/jts.21731" target="_blank" rel="noreferrer noopener">10.1002/jts.21731</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Berkowitz S J
Children
conditioned fear
Cortisol
Delahanty D L
Journal of Traumatic Stress
Maccani M A
Memory
MORPHINE
Nugent N R
pediatric injury patients
posttraumatic-stress-disorder
Propranolol
Psychiatry
Psychology
Stress
Symptoms
traumatic
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/jts.20517" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jts.20517</a>
Pages
282–287
Issue
2
Volume
23
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The efficacy of early propranolol administration at reducing PTSD symptoms in pediatric injury patients: A pilot study.
Publisher
An entity responsible for making the resource available
Journal of Traumatic Stress
Date
A point or period of time associated with an event in the lifecycle of the resource
2010
2010-04
Subject
The topic of the resource
TREATMENT of post-traumatic stress disorder; STRESS (Psychology); GENDER differences (Psychology); CHILDREN'S injuries; BLIND experiment; PHARMACOLOGY; PLACEBOS (Medicine); PROPRANOLOL
Creator
An entity primarily responsible for making the resource
Nugent Nicole R; Christopher Norman C; Crow John P; Browne Lorin; Ostrowski Sarah; Delahanty Douglas L
Description
An account of the resource
Initial research supports the use of propranolol to prevent posttraumatic stress disorder (PTSD); research has not examined pharmacological prevention for children. Twenty-nine injury patients (ages 10–18 years old) at risk for PTSD were randomized to a double-blind 10-day trial of propranolol or placebo initiated within 12 hours postadmission. Six-week PTSD symptoms and heart rate were assessed. Although intent-to-treat analyses revealed no group differences, findings supported a significant interaction between gender and treatment in medication-adherent participants, ΔR2 = .21. Whereas girls receiving propranolol reported more PTSD symptoms relative to girls receiving placebo, ΔR2 = .44, boys receiving propranolol showed a nonsignificant trend toward fewer PTSD symptoms than boys receiving placebo, ΔR2 = .32. Findings inform gender differences regarding pharmacological PTSD prevention in youth. [ABSTRACT FROM AUTHOR]
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/jts.20517" target="_blank" rel="noreferrer noopener">10.1002/jts.20517</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2010
Akron Children's Hospital
BLIND experiment
Browne Lorin
CHILDREN'S injuries
Christopher Norman C
Crow John P
Delahanty Douglas L
Department of Emergency Medicine
Department of Pediatrics
GENDER differences (Psychology)
Journal of Traumatic Stress
NEOMED College of Medicine
Nugent Nicole R
Ostrowski Sarah
pharmacology
PLACEBOS (Medicine)
Propranolol
STRESS (Psychology)
TREATMENT of post-traumatic stress disorder
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.nlm.2014.02.001" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.nlm.2014.02.001</a>
Pages
122–129
Volume
112
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pharmacological modulation of acute trauma memories to prevent PTSD: considerations from a developmental perspective.
Publisher
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Neurobiology of learning and memory
Date
A point or period of time associated with an event in the lifecycle of the resource
2014
2014-07
Subject
The topic of the resource
*Memory; Adrenergic beta-Antagonists/*pharmacology; Adult; Animals; Child; Cortisol; Developmental; Episodic; Humans; Hydrocortisone; Hydrocortisone/*biosynthesis/therapeutic use; Hypothalamo-Hypophyseal System/*metabolism; Pituitary-Adrenal System/*metabolism; Post-Traumatic/*metabolism/prevention & control; Posttraumatic stress disorder; Propranolol; Propranolol/*pharmacology; Stress Disorders; Sympathetic Nervous System/*metabolism; Trauma memories
Creator
An entity primarily responsible for making the resource
Hruska Bryce; Cullen Patrick K; Delahanty Douglas L
Description
An account of the resource
Estimates of the lifetime prevalence of posttraumatic stress disorder (PTSD) in American adults range from 6.4% to 6.8%. PTSD is associated with increased risk for comorbid major depression, substance use disorder, suicide, and a variety of other mental and physical health conditions. Given the negative sequelae of trauma/PTSD, research has focused on identifying efficacious interventions that could be administered soon after a traumatic event to prevent or reduce the subsequent incidence of PTSD. While early psychosocial interventions have been shown to be relatively ineffective, early (secondary) pharmacological interventions have shown promise. These pharmacological approaches are largely based on the hypothesis that disruption of altered stress hormone levels and the consequent formation of trauma memories could protect against the development of PTSD. The present manuscript reviews the literature regarding the role of peri-traumatic stress hormones as risk factors for the development of PTSD and reviews evidence for the efficacy of exogenously modulating stress hormone levels to prevent/buffer the development of PTSD symptoms. Whereas prior literature has focused primarily on either child or adult studies, the present review incorporates both child and adult studies in a developmental approach to understanding risk for PTSD and how pharmacological modulation of acute memories may buffer the development of PTSD symptoms.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.nlm.2014.02.001" target="_blank" rel="noreferrer noopener">10.1016/j.nlm.2014.02.001</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Memory
2014
Adrenergic beta-Antagonists/*pharmacology
Adult
Animals
Child
Cortisol
Cullen Patrick K
Delahanty Douglas L
Developmental
Episodic
Hruska Bryce
Humans
Hydrocortisone
Hydrocortisone/*biosynthesis/therapeutic use
Hypothalamo-Hypophyseal System/*metabolism
Neurobiology of learning and memory
Pituitary-Adrenal System/*metabolism
Post-Traumatic/*metabolism/prevention & control
Posttraumatic stress disorder
Propranolol
Propranolol/*pharmacology
Stress Disorders
Sympathetic Nervous System/*metabolism
Trauma memories